Involve both genetic and environmental factors to build monkey models of mental disorders

正Dear Editor,Mental diseases,such as schizophrenia,are typically the result of multiple abnormalities,including neurobiological,psychological and sociological processes,particularly the environmental and genetic disorders(Bailey,2000).Consequently,in psychic medicine,animal models should be developed via methods consistent with their associated theories of mental disorders.However,many conventional models are constructed via genetic manipulations or surgical operations to the nervous system(Bezard,2006,van der Staay,2006,2009),e.g.administrate animals with agonists or antagonists of various neurotransmitters or drugs to reproduce human mental disorders.The usage of these methods,which should be considered as simple neuro-pharmacological