Silicon bioavailability studies in young rapidly growing rats and turkeys fed semipurified diets

Two experiments were conducted using completely randomized designs to study the bioavailability of Si from three sources to growing rats and turkeys fed semipurified diets. The basal diets were dextrose-egg albumin for rats and dextrose-casein for turkeys. The Si sources were tetraethylorthosilicate (TES), sodium silicate (NaSil), and sodium zeolite A (NaZA). Rats and turkeys were supplemented at 500 and 270 ppm Si, respectively, from each source. A control group of unsupplemented rats and turkeys was included in each experiment. In general, irrespective of Si source, Si supplementation slowed (p < 0.05 orp < 0.01) growth rates in both rats and turkeys. Although dietary Si supplementation reduced (p < 0.05) plasma Mg levels and liver Zn concentrations in rats, it increased (p < 0.05) plasma P and reduced (p < 0.05) plasma Cu levels in turkeys. Rats on TES had significantly slower (p < 0.05 orp < 0.01) growth rates (5–10%) than those on NaSil or NaZA. In rats, NaZA and TES reduced (p < 0.05) hemoglobin concentrations and plasma Zn, respectively. However, plasma Mg levels were higher (p < 0.05) in TES than NaSil-or NaZA-fed rats. The source of the dietary Si did not affect (p < 0.05) the organ weights of rats and their mineral concentrations. Turkeys on TES diets grew at a significantly faster (p < 0.05) rate (15%) than those on NaSil or NaZA diets during the first 2 wk of experimentation. However, after 4 wk, there were no significant (p > 0.05) differences in growth between the Si sources. In turkeys, NaZA increased (p < 0.05) hematocrit levels and plasma Mg levels. Turkeys on NaZA diets had larger (p < 0.05) hearts and livers than those on NaSil but not TES. Liver Mn content was higher (p < 0.05) in turkeys on NaSil than TES or NaZA. Heart Zn was lower (p < 0.05) in turkeys on NaSil than TES, but not NaZA.     

Copper-silicon interaction studies in young, rapidly growing turkeys fed semipurified starter diets

A 3 × 3 factorial experiment was conducted to study the interactions between Cu and Si in growing turkeys fed a basal dextrosecasein semipurified diet supplemented at 0, 270, and 540 ppm Si, and 2, 8, and 75 ppm Cu levels of inclusion. There were no significant (p>0.05) Cu, Si, or Cu-Si interaction effects on turkey growth. However, there were significant (p<0.05) Si effects on hemoglobin concentrations, and Cu−Si interaction effects on hematocrit and plasma Mg levels (p<0.01). Plasma Ca, P, Zn, Cu, total cholesterol, and serum alkaline phosphatase activity were not affected (p>0.05) by Cu, Si, or Cu−Si interaction. Heart and liver weights were affected (p<0.05) by the Cu-Si interaction. In general, a 8-ppm Cu supplemental level prevented cardiac hypertrophy only in the presence of 270 or 540 ppm Si inclusion in the diets. There were significant (p<0.05) Cu effects on liver Cu and Mn and heart Zn concentrations, Si effects on liver Mn levels, and Cu-Si interaction on liver Zn concentrations. Within the 0- and 270-ppm Si groups, Cu-deficient turkeys (2 ppm Cu) had higher liver Zn levels but not within the 540-ppm Si group. The Cu-Si interaction did not affect (p>0.05) concentrations of Cu in the heart and liver tissues. It is postulated that the Cu-Si interactions demonstrated in this study could have profound implications on the cardiovascular and skeletal health of birds.