提高生物课堂教学有效性——新课程背景下探究教学法的灵活运用

新课程的实施需要运用探究教学法,广大高中生物教师对这一教法的运用还在摸索之中。通过拟从探究教学法的运用,对提高高中生物课堂教学有效性的作用,提出实践性的教学建议。     

Mesozoic tectono-sedimentary evolution of Rocca Busambra in western Sicily

The Rocca Busambra ridge in western Sicily is a shallow to pelagic Meso-Cenozoic carbonate structural unit of the Sicilian Chain with a variety of tectono-sedimentary features. Palaeofaults, unconformities (buttress unconformity, onlap, downlap), a network of neptunian dykes with several infilling generations, several large hiatuses, different facies and lateral facies changes, and erosional submarine and subaerial surfaces are observed. Detailed fieldwork and structural analyses have indicated the occurrence of fault planes with different orientations. These data, combined with facies studies and physical-stratigraphy analyses, allow for the distinction of different depositional regions. A lateral change from an open-marine carbonate platform with a stepped fault margin (located in the westernmost sector) to a deeper basinal depositional setting in the east, in the context of an upper slope scalloped margin and base-of-slope systems with talus breccias, is envisaged here. Extensional to transtensional tectonic pulses punctuated the sedimentary evolution during Early Toarcian, Late Jurassic, Early Cretaceous, Late Cretaceous, and Early Miocene times. The collected data show that most fault planes have preserved their original orientations throughout the reactivation processes. The reconstructed Meso-Cenozoic tectono-sedimentary evolution is closely related to the late syn-rift and post-rift tectonic evolution of the Tethyan continental margin.     

Nanotechnology-based intelligent drug design for cancer metastasis treatment

Traditional chemotherapy used today at clinics is mainly inherited from the thinking and designs made four decades ago when the Cancer War was declared. The potency of those chemotherapy drugs on in-vitro cancer cells is clearly demonstrated at even nanomolar levels. However, due to their non-specific effects in the body on normal tissues, these drugs cause toxicity, deteriorate patient's life quality, weaken the host immunosurveillance system, and result in an irreversible damage to human's own recovery power. Owing to their unique physical and biological properties, nanotechnology-based chemotherapies seem to have an ability to specifically and safely reach tumor foci with enhanced efficacy and low toxicity. Herein, we comprehensively examine the current nanotechnology-based pharmaceutical platforms and strategies for intelligent design of new nanomedicines based on targeted drug delivery system (TDDS) for cancer metastasis treatment, analyze the pros and cons of nanomedicines versus traditional chemotherapy, and evaluate the importance that nanomaterials can bring in to significantly improve cancer metastasis treatment.     

《细胞生物学》课堂教学模式改革的探索与实践

为了更好地培养学生的能力,必须对传统的教学模式进行改革。针对传统教学模式下生物工程专业细胞生物学教学中学生积极性和主动性不强、缺少综合能力训练内容、作业抄袭、新知识与新进展反映不理想等问题,通过设定合理题目、规定格式和内容、单独报告、择优讲演等方式,利用学生的好胜心理、竞争性和成就感等,提出了新的教学模式。教学实践证明,新的教学模式能够充分调动学生学习的积极性和主动性,提高学生对专业知识的综合与归纳能力、表达演讲能力和电脑使用技能,同时也避免了作业抄袭现象的发生,强化了学生的自信心。另外,也对新模式中存在的问题进行了思考与建议。     

《生物化学》重要章节——《糖酵解》课堂教学体会与思考

《生物化学》是生物类专业的一门重要学科基础课程。《糖酵解》属于《糖代谢》一章的其中一节。本节内容的学习需应用前一章《生物氧化与氧化磷酸化》的已学知识,也是《糖代谢》后续内容《三羧酸循环》及《糖异生》等的学习基础,因此是本章教学的重要环节,教学效果的好坏将影响到《糖代谢》一章的整体教学质量。课程教学团队在多年课堂教学实践基础上,对《糖酵解》一节的课堂教学体会及思考进行了总结,供大家交流与参考。