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肿瘤是各种原因导致多基因突变累积和相互作用形成的基因网络调控的结果,通过干预致瘤因子可能达到治疗肿瘤或改变肿瘤特性的目的。小分子RNA因可调控基因表达而被作为基因治疗的有效武器。本文结合我们课题组在小分子RNA方面的研究成果,对外源性的siRNA和内源性的miRNA在肿瘤治疗、治疗前景,以及siRNA和miRNA的联系与区别等方面作一综述。 相似文献
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A rumor transmission model with various contact interactions 总被引:2,自引:0,他引:2
Kawachi K Seki M Yoshida H Otake Y Warashina K Ueda H 《Journal of theoretical biology》2008,253(1):55-60
We consider a rumor transmission model with various contact interactions and explore what effect such interactions have on the spread of a rumor, in particular whether they can explain the rumor recursion. Through mathematical analysis and computer simulations, we conjecture that rumor recursion remains a major challenge to mathematical models of rumors beyond our model proposed here. 相似文献
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