Studies of Songbeinone,A New Fritillaria Alkaloid Identified from the Bulb of Fritillaria unibracteata

A compound C was isolated from the dry bulbs of Fritillaria unibracteata Hsiao et K. C: Hsia which belongs to a main resource species of traditional Chinese drug “Chuan Bei-mu” in Chinese Pharmacopoeia (1990 ed.). It was identified as D/E cis(22R, 25S)-20-deoxy-3β-hydroxyl-6-carbonyl-5α, 14α, 17β-cevanine by means of spectroscopic methods. It is a new alkaloid of 5α-cevanine group of isosteroidal alkaloids being attributed to the characteristic constituents of this genus, named as songbeinone.