妊娠合并甲状腺功能亢进症23 例临床分析

目的:探讨妊娠合并甲状腺功能亢进症的孕妇的妊娠结局,对母体造成的影响,抗甲状腺药物的使用情况及分娩方式。方法:对23例甲状腺功能亢进孕妇进行了回顾性分析,观察该病对孕妇的影响,对母儿造成的不良结局。结果:23例甲状腺功能亢进孕妇合并轻度妊娠高血压综合征的2例,中度4例,重度2例。合并心衰6例,合并胎膜早破5例,胎盘粘连2例,甲状腺危象1例,胎盘早剥1例,产后出血1例,前置胎盘1例。23例甲状腺功能亢进顺产6例,产钳1例,胎头吸引1例,剖宫产15例。出现早产9例,其中5例为医源性早产。胎儿宫内窘迫6例,死胎1例。结论:妊娠合并甲状腺功能亢进症常危及母婴健康,为降低母儿风险,孕前需很好地控制病情,孕期密切监控,合理治疗。     

二化螟人工饲料关键因子的优化及其优化配方的饲养效果

采用5因子4水平正交试验,将作者在以前筛选出的二化螟Chilosuppressalis(Walker)人工饲料的5个关键因子进行了进一步的优化,并得出了二化螟人工饲料的优化配方,其成分如下:稻茎粉18.75g、大豆粉15.00g、麦芽粉15.00g、稻糠粉6.25g、茭白茎粉7.50g、干酪素10.00g、酵母粉18.75g、纤维素7.50g、蔗糖15.00g、葡萄糖7.50g、维生素C7.50g、复合维生素B3.00g、胆固醇0.375g、氯化胆碱0.25g、Beck氏盐2.50g、山梨酸1.35g、琼脂13.49g和自来水809.25g。通过连续3代继代饲养试验,比较了该优化配方和二化螟天然饲料水稻茎的饲养效果。结果表明,在一些关键指标上(如存活率、化蛹率和羽化率等),所优化的二化螟人工饲料配方的饲养效果明显的好于其天然饲料水稻茎的;而在许多其它的指标上(如蛹期、成虫期、产卵量、卵期和孵化率等),该优化配方对二化螟的饲养效果与水稻茎的相当;但该配方饲养的二化螟在第3代时幼虫历期明显的比水稻茎的有所延长。     

Simulating forest ecosystem response to climate warming incorporating spatial effects in north-eastern China

Aim Predictions of ecosystem responses to climate warming are often made using gap models, which are among the most effective tools for assessing the effects of climate change on forest composition and structure. Gap models do not generally account for broad‐scale effects such as the spatial configuration of the simulated forest ecosystems, disturbance, and seed dispersal, which extend beyond the simulation plots and are important under changing climates. In this study we incorporate the broad‐scale spatial effects (spatial configurations of the simulated forest ecosystems, seed dispersal and fire disturbance) in simulating forest responses to climate warming. We chose the Changbai Natural Reserve in China as our study area. Our aim is to reveal the spatial effects in simulating forest responses to climate warming and make new predictions by incorporating these effects in the Changbai Natural Reserve. Location Changbai Natural Reserve, north‐eastern China. Method We used a coupled modelling approach that links a gap model with a spatially explicit landscape model. In our approach, the responses (establishment) of individual species to climate warming are simulated using a gap model (linkages ) that has been utilized previously for making predictions in this region; and the spatial effects are simulated using a landscape model (LANDIS) that incorporates spatial configurations of the simulated forest ecosystems, seed dispersal and fire disturbance. We used the recent predictions of the Canadian Global Coupled Model (CGCM2) for the Changbai Mountain area (4.6 °C average annual temperature increase and little precipitation change). For the area encompassed by the simulation, we examined four major ecosystems distributed continuously from low to high elevations along the northern slope: hardwood forest, mixed Korean pine hardwood forest, spruce‐fir forest, and sub‐alpine forest. Results The dominant effects of climate warming were evident on forest ecosystems in the low and high elevation areas, but not in the mid‐elevation areas. This suggests that the forest ecosystems near the southern and northern ranges of their distributions will have the strongest response to climate warming. In the mid‐elevation areas, environmental controls exerted the dominant influence on the dynamics of these forests (e.g. spruce‐fir) and their resilience to climate warming was suggested by the fact that the fluctuations of species trajectories for these forests under the warming scenario paralleled those under the current climate scenario. Main conclusions With the spatial effects incorporated, the disappearance of tree species in this region due to the climate warming would not be expected within the 300‐year period covered by the simulation. Neither Korean pine nor spruce‐fir was completely replaced by broadleaf species during the simulation period. Even for the sub‐alpine forest, mountain birch did not become extinct under the climate warming scenario, although its occurrence was greatly reduced. However, the decreasing trends characterizing Korean pine, spruce, and fir indicate that in simulations beyond 300 years these species could eventually be replaced by broadleaf tree species. A complete forest transition would take much longer than the time periods predicted by the gap models.     

微生物学本硕博Seminar混合式教学模式的构建及应用

以微生物学本、硕、博Seminar混合式教学模式为核心,通过菌物学科研专题开题设计、文献精读及试验进展汇报的课堂教学,对微生物学本、硕、博Seminar混合式教学模式的模型构建、具体实施、结果评估及教学效果进行了详细解析。结果表明,微生物学本、硕、博Seminar教学法可有效催促教师不断提升教学质量,拓宽本科生视野提高学生的主观能动性,锻炼硕士生科研能力及试验教学能力,增强博士生系统科研能力及团队领导能力。     

无融合生殖油菜AMR—1花托离体培养的研究

报道了不同激素浓度对无融合生殖没菜花托器官分化效果的研究,结果显示：（１）以ＭＳ为基本培养基,以带有子房和花柄的花托为外植体离体培养,花托、花柄切口部位直接芽诱导的最佳激素配比为４．０ｍｇ／Ｌ６－ＢＡ＋０．０１ｍｇ／Ｌ ＮＡＡ,频率为５８．８２％,花托、花柄部位先形成愈伤组织,继而分化出丛生芽的最佳激素配比为５．０ｍｇ／Ｌ ６－ＢＡ＋０．５ｍｇ／Ｌ ＮＡＡ,频率为８４．００％;（２）腋芽增殖的最佳     

Standardizing the analysis of conditioned fear in rodents: a multidimensional software approach

Data comparability between different laboratories strongly depends on the individually applied analysis method. This factor is often a critical source of variation in rodent phenotyping and has never been systematically investigated in Pavlovian fear conditioning paradigms. In rodents, fear is typically quantified in terms of freezing duration via manual observation or automated systems. While manual analysis includes biases such as tiredness or inter‐personal scoring variability, computer‐assisted systems are unable to distinguish between freezing and immobility. Consequently, the novel software called MOVE follows a semi‐automatized approach that prefilters video sequences of interest for the final human judgment. Furthermore, MOVE allows integrating additional data sources (e.g. force‐sensitive platform, EEG) to reach the most accurate and precise results. MOVE directly supports multi‐angle video recordings with webcams or standard laboratory equipment. The integrated manual key logger and internal video player complement this all‐in‐one software solution. Calculating the interlaboratory variability of manual freezing evaluation revealed significantly different freezing scores in two out of six laboratories. This difference was minimized when all experiments were analyzed with MOVE. Applied to a genetically modified mouse model, MOVE revealed higher fear responses of CB1 deficient mice compared to their wild‐type littermates after foreground context fear conditioning. Multi‐angle video analysis compared to the single‐camera approach reached up to 15% higher accuracy and two fold higher precision. Multidimensional analysis provided by integration of additional data sources further improved the overall result. We conclude that the widespread usage of MOVE could substantially improve the comparability of results from different laboratories.