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Introduction
Open access breast clinics are now widely available and immediate reporting of FNAs of the breast has become an established part of the triple approach to the management of breast disease 1 .
We report the unexpected findings of a case of Hodgkin's disease at such a clinic. The patient was a young woman who initially was thought by both her general practitioner and surgeon to have a fibroadenoma in the axillary tail region of her right breast. The FNA of this lump showed the features of Hodgkin's disease but with widespread necrosis, which was unusual and potentially misleading and which we wish to highlight. A lymph node biopsy confirmed the diagnosis and showed that the patient was suffering from the syncytial variant of nodular sclerosing Hodgkin's disease (NSHD).
This variant probably accounts for about 5% of cases of Hodgkin's disease 2 . Necrosis is a common feature of NSHD; it can range from minute scattered foci to more extensive necrosis of nodules or even involve the entire lymph node.  相似文献   
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This paper deals with the effects of agronomic practices on parasite life cycles, and the design of integrated crop protection strategies. Cropping systems have a large effect on the size of the primary inoculum and its localisation, on the development and spread of epidemics, and on the coordination of the life cycle of cultivated plants and that of their parasites. They can disrupt ecological equilibria, either favouring or disfavouring the pathogens. By combining information concerning the effects of agricultural techniques on diseases and the physiological effects of diseases on growth and crop production, it is now possible to develop new crop management systems, in which the use of non-chemical methods for preventing diseases is a priority. However, the current knowledge need to be completed by studies on other scales, particularly of the effect of cropping systems on the genetics of disease populations integrating more completely the 'long-term' dimension of sustainable agriculture.  相似文献   
3.
The term “precision”, involving the contact between the tips of thumb and the index is generally attributed to humans, tool use and associated with morphological criteria. Identified in fossils, those criteria are used to assert that they manipulated tools. Observations of 69 individuals belonging to Catarrhines and Platyrrhines allowed us to quantify surfaces of fingers used during simple tasks of grasping both small and large objects, as well as during complex tasks of proto-tool and tool use. We concluded that precision grasping is not peculiar to humans and that it is not systematically linked to tool use. These results allowed us to discuss morphological traits used till now to deduce precision and tool use from the fossils. Besides, our analyses let appear a recurrent proximity between the capuchins and the humans, species distant in a phylogenetic point of view, suggesting the possible existence of functions and close behaviours in spite of great genetic distinctions.  相似文献   
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