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Fengzhi Li 《Molecules and cells》2009,27(4):491-492
We present the result of our research on the tumorigenic ability of single cell clones isolated from an aggressive murine
breast cancer cell line in a matched allografting mouse model. Tumor formation is basically dependent on the cell numbers
injected per location. We argue that in vivo tumor formation from single cell clones, isolated in vivo from cancer cell lines, may not provide conclusive evidence to disprove the cancer stem cell (CSC) theory without additional
data. 相似文献
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