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1.
中药凌霄花的研究进展 总被引:1,自引:0,他引:1
本文对中药凌霄花的研究进展进行了综述,包括生药学研究、化学成分研究、药理学研究及临床应用。 相似文献
2.
Kalpesh B. Ishnava Jenabhai B. Chauhan Mahesh B. Barad 《Saudi Journal of Biological Sciences》2013,20(1):69-74
In the present study, in vitro anticariogenic potential of ethyl acetate, hexane and methanol and aqueous extracts of plant leaves of Eucalyptus globules Labill. were evaluated by using four cariogenic bacteria, Lactobacillus acidophilus, Lactobacillus casei, Staphylococcus aureus and Streptococcus mutans. Agar well diffusion method and minimum inhibitory concentration (MIC) were used for this purpose. The ethyl acetate extracted fraction of plant leaves showed good inhibitory effects against all selected bacteria. In Eucalyptus globules, hexane and ethyl acetate extracts found highly effective against, Lactobacillus acidophilus with MIC value of 0.031 and 0.062 mg/mL, respectively. Qualitative phytochemical investigation of above extracts showed the presence of alkaloids, phenolic compounds, steroids, cardiac glycosides and terpenes. Based on the MIC value and bioautography, ethyl acetate of plant leaf was selected for further study. Further investigation on the structure elucidation of the bioactive compound using IR, GC-MS and NMR techniques revealed the presence of alpha-farnesene, a sesquiterpene. Eucalyptus globules plant leaf extracts have great potential as anticariogenic agents that may be useful in the treatment of oral disease. 相似文献
3.
Bilal A. Zargar Mubashir H. Masoodi Bahar Ahmed Khan Seema Akbar 《Phytochemistry letters》2013,6(2):261-266
Paeonia emodi (Peony) is a well known Himalayan medicinal plant used in the treatment of hypertension, palpitations, asthma, uterine diseases, colic, bilious obstructions and has also been used as an anticoagulant. Many of these ethnomedicinal properties have been experimentally proven in different animal models. The present work reviews the ethnopharmacology, therapeutic potential and phytochemistry of P. emodi. Different classes of natural products like triterpenoids, monoterpenoids, phenolics and tannins have been isolated from the species. These compounds possess wide therapeutic profile like cardiovascular and airway relaxant, lipoxygenase and β-Glucuronidase inhibitory and free radical scavenging properties. 相似文献
4.
This review, based on nearly 25 literary sources, discusses the chemical nature and biological effects of the whole plant of Lancea tibetica Hook. f. et Thoms (Scrophulariaceae). Several types of chemical constituents have been isolated from Lancea tibetica (LT) including 34 phenolpropanoids (16 lignans, 5 neolignans, 5 nonanones, 4 phenylpropanoid glycosides, and 4 propanediols), 9 flavones, 6 triterpenoids, and 11 amino acids. Various extracts and individual compounds derived from this species have been determined to possess a variety of pharmacological effects, such as anti-tumour and antioxidant functions. The results of data analysis on the chemical and pharmacological characteristics of LT support the view that this plant has many therapeutic properties, suggesting its potential as an effective herbal remedy. Finally, suggestions for further avenues of research on the chemical and pharmacological properties of LT and ways in which to further exploit LT are presented in this review. 相似文献
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Origanum onites L., known as Turkish oregano, has great traditional, medicinal, preservative, and commercial importance. It is used for the treatment of several kinds of ailments, such as gastrointestinal disorders, diabetes, high cholesterol, leukemia, bronchitis, etc. In this review, traditional use, phytochemistry, and pharmacology of O. onites reported between 1988 and 2014 were discussed. This review was prepared based on literature survey on scientific journals and books from libraries and electronic sources, such as Web of Science, PubMed, Scopus, Google Scholar, etc. All databases were searched up to June 2014. Several different classes of terpenoids, triterpene acids, phenolic acids, hydroquinones, flavonoids, hydrocarbons, sterols, pigments, fatty acids, tocopherols, and inorganic compounds were detected mainly in the aerial parts of this plant. Pharmacological studies revealed that extracts obtained from several solvents and individual compounds exhibited antimicrobial, antiviral, antioxidant, insecticidal, anticancer, hepatoprotective, genotoxic, antidiabetic, cholinesterase inhibitory, anti‐inflammatory, analgesic activities, etc. O. onites, in general, exhibited remarkable activity potential in almost all test systems. The results of toxicity studies indicated that O. onites did not show any significant toxicity and mutagenicity on Drosophila and Salmonella. Toxicity of the extracts/essential oils and also individual compounds should be evaluated on mammalian cells to ensure their safety. The bioactivity of individual compounds aside from terpenoids should also be assessed in detail. Additionally, mode of action for the bioactive compounds should be evaluated to understand the complex pharmacological effects of these phytochemicals. 相似文献
7.
Si-Yue Chen Chang-An Geng Yun-Bao Ma Xiao-Yan Huang Xiao-Tong Yang Li-Hua Su Xiao-Feng He Tian-Ze Li Zhen-Tao Deng Zhen Gao Xue-Mei Zhang Ji-Jun Chen 《Bioorganic & medicinal chemistry》2019,27(15):3299-3306
Gastrodia elata is a famous traditional Chinese herb with medicinal and edible application. In this study, nine polybenzyls (1?9), including six new ones (2?5, 7 and 9), were isolated from the EtOAc extract of G. elata. Five compounds 1, 3, 4, 6 and 8 were found to activate melatonin receptors. Especially, compound 1 showed agonistic effects on MT1 and MT2 receptors with EC50 values of 237 and 244 μM. For better understanding their structure-activity relationships (SARs), ten polybenzyl analogs were further synthesized and assayed for their activities on melatonin receptors. Preliminary SARs study suggested that two para-hydroxy groups were the key pharmacophore for maintaining activity. Molecular docking simulations verified that compound 1 could strongly interact with MT2 receptor by bonding to Phe 118, Gly 121, His 208, Try 294 and Ala 297 residues. 相似文献
8.
Joseph K. Bailey Jennifer A. Schweitzer Brian J. Rehill Duncan J. Irschick Thomas G. Whitham Richard L. Lindroth 《Biological invasions》2007,9(6):715-722
The global ecological impacts of introduced and exotic species can be dramatic, leading to losses in biodiversity and ecosystem
“meltdown”, however, the evolutionary impacts of introduced species are much less understood. Further, very few studies have
examined whether mammalian herbivores can act as agents of natural selection for plant traits. We examined the hypothesis
that variation in aspen phytochemistry resulted in selective herbivory by Cervus elaphus (elk), an introduced mammalian herbivore. With the experimental removal of a large elk exclosure, elk selectively eliminated
60% of an aspen population previously protected from herbivory resulting in a dramatic shift in the phytochemical composition
of the aspen forest. Selection gradients (β) varied from 0.52 to 0.66, well above average relative to other studies of selection.
These results indicate that introduced herbivores can have rapid evolutionary consequences even on long lived native species.
Because there are fundamental links between phytochemistry, biodiversity and ecosystem processes, the effects of an introduced
herbivore are likely to have cascading impacts on the services ecosystems provide. 相似文献
9.
大气CO2浓度升高对森林食叶昆虫的潜在影响 总被引:2,自引:0,他引:2
评述了大气CO2浓度升高对森林食叶昆虫的影响,昆虫对森林取食为害水平的潜在变化,以及研究中的主要实验方法.大气CO2浓度升高通过引起叶片化学变化进而影响食叶昆虫个体的取食和生长;但物种对环境变化反应的特异性、植物化学对高浓度CO2的反应强度、昆虫对植物生理变化的敏感性和适应性、研究周期的长短、其它环境因子的协同效应以及不同实验中植物生长条件和研究方法的差异均将影响昆虫反应的方向和强度;CO2气体浓度增高本身可能不足以对食叶昆虫个体的新陈代谢构成影响;大气CO2浓度升高也可能影响森林食叶昆虫种群的大小. 相似文献
10.
In this work, an interesting potential application of phytochemistry is reported. In particular, we employed the Sporne diagrams to provide information about the evolution of some different Lamiaceae species in relation to their content in secondary metabolites. In more details, fifteen species belonging to six different genera were studied i.e. Ajuga L., Galeopsis L., Melittis L., Sideritis L., Stachys L. and Teucrium L. The selected secondary metabolites were iridoids because of their wide occurrence and distribution within all the family, thus providing a more accurate and general overview. Nineteen different compounds of this class were identified in the studied species. The aim of this work was to verify if the evolutionary data available in literature for the studied species and based on molecular studies, matched with those obtained from a more phytochemical approach or not. The final objective was to ascertain a correspondence between these two opposite methods. The results of this study clearly showed that, only in some cases, this correspondence was present. This may suggest the possibility to use both methods for drawing phylogenetic trees of plants. Anyway, this study is not general and is quite limited in studied species and in collection areas and does not intend to affirm its absolute accuracy even though it may be a good starting point for future researches in this field. 相似文献