排序方式: 共有1条查询结果,搜索用时 0 毫秒
1
1.
F. Kees M. Bucher G. Mair H. Grobecker 《Journal of chromatography. B, Analytical technologies in the biomedical and life sciences》2001,753(2):50
A high-performance liquid chromatographic method is described for the determination of opipramol in human plasma. Opipramol was extracted into tert.-butylmethyl ether, separated on a cyanopropyl silica column and detected at 254 nm. Imipramine was used as internal standard. The limit of quantitation was 250 pg/ml using 1.5 ml plasma. Precision was better than 9%, inaccuracy less than 8%. The assay is more sensitive than previously published methods, and it has been applied to the analysis of plasma samples from a pharmacokinetic study. 相似文献
1