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1.
Object exploration is an increasingly popular experimental paradigm in behavioral sciences. We have begun a series of studies with mice specifically looking at the parameters that influence behaviors in this test. The aim of the present study was to examine the effect of object type on performance in the object exploration test. More specifically, adult male C57BL/6J mice were trained and tested using objects that could be climbed (CLIMB) or with those that could only be touched (TOUCH). The results show that activity is affected by the presentation of objects, with object type interacting with some of these changes. C57 mice explored objects that can be climbed over significantly longer than objects that can only be touched and a more rapid habituation was observed using objects that could only be touched. Robust recognition memory was observed in both groups of mice, however mice in the CLIMB group exhibited a significantly greater discrimination index compared to mice in the TOUCH group. Taken together, these findings demonstrate that the selection of objects is of critical importance and it is recommended that special attention be given to the functional (affordant) properties of the objects to-be-used in future studies. 相似文献
2.
Dorothe Valance Alain Boissy Grard Desprs Ccile Arnould Caroline Galand Anglique Favreau Paul Constantin Christine Leterrier 《Applied animal behaviour science》2008,112(3-4):307-320
In intensive rearing, birds are exposed to frequent changes in both their social and physical environments, and this can have an impact on animal welfare under commercial conditions. The aim of the present study was to compare the emotional responses induced by social and non-social changes and to study the influence of the familiarity on these responses.Twenty-two female quail were first reared with a ball in 15–20-individual groups for 3 weeks from hatching. Then, each experimental subject was allocated either a familiar congener (CONG) or a familiar object (BALL). At 6 weeks of age the birds were fitted with a telemetric device to collect motor and cardiac activities. After that, each subject was exposed first to a separation from its cage-mate/familiar object, and secondly to the (re-)introduction of either the cage-mate/familiar object or of an unknown conspecific/another ball. Emotional responses were assessed through behavioural reactions and heart rate variability.Before being separated, both BALL and CONG quail showed stereotyped pacing that was more pronounced in BALL quail. BALL quail were not affected by the ball withdrawal, unlike CONG quail which reacted to the separation from their cage-mate by reducing activity and exploratory behaviour (P < 0.05). After the re-introduction, BALL quail remained closer to their ball and CONG quail spent more time with “stretched necks” than before the separation (P < 0.05). Surprisingly, CONG quail showed less stereotyped pacing when their partner was removed and recovered the initial level of stereotyped behaviour when their cage-mate was re-introduced (P < 0.01). Likewise, CONG quail also recovered the initial values of heart rate after the re-introduction of their cage-mate, indicating an increase in sympathetic activity compared to the isolation period. When the unfamiliar congener or ball was introduced in their cage, BALL quail pecked the unknown ball more than the familiar ball and had more contact with it (P < 0.05) and CONG quail had more contact with the unknown congener than with the cage-mate (P < 0.05).In conclusion, the quail appeared to experience a negative affective state before being separated, and there was no clear evidence of negative emotion in quail in response to the separation from either a social partner or an inanimate object. Nevertheless, the emotional responses of the quail in reaction to the (re-)introduction was influenced by the familiarity of the congener or the ball. Finally, changes in the quail's social environment induced more behavioural and cardiac modifications than changes in its non-social environment. 相似文献
3.
Mabel C. Fraga-Marques Egberto G. Moura Isis H. Trevenzoli Magna C.F. Passos Alex C. Manhães 《Hormones and behavior》2009,55(2):272-279
Leptin treatment during lactation programmes for leptin resistance at adulthood, evidenced by hyperleptinaemia, hyperphagia and overweight. Since leptin is known to affect stress response, emotional behaviour and memory/learning performance, the objective of the present study was to evaluate whether neonatal hyperleptinaemia programmes anxiety-like and novelty-seeking behaviours as well as memory/learning in adult male rats. During the first 10 days of lactation (from PN1 to PN10), pups were s.c. injected once per day with either 50 μL of saline (SAL) or murine leptin (LEP — 8 μg/100 g of body mass, saline diluted). Serum leptin was assessed at PN10 and at PN150. Two separate experiments were carried out: 1) experiment one: at PN137, 29 SAL and 30 LEP rats were tested in the elevated plus-maze (EPM) and, at PN142, their behaviour was assessed in the hole board (HB) arena; 2) experiment two: at PN140, a different group of rats consisting of 53 SAL and 56 LEP animals were tested in the radial arm water maze (RAWM). Serum leptin concentration was higher in the LEP group at PN10 and at PN150. LEP animals spent significantly less time in the open arms of the EPM. Furthermore, the number of nose-pokes in the HB arena was higher in LEP rats. There were no differences between groups regarding latency to find the hidden platform in the RAWM. Our results suggests that a central mechanism of leptin resistance at adulthood, caused by neonatal hyperleptinaemia, is associated with an increased level of anxiety and also that it intensifies novelty seeking-behaviour. 相似文献
4.
Fear is a concept comprising several dimensions, but the nature of these dimensions and the relationships between them remain elusive. To investigate these dimensions in birds, we have used two genetic lines of quail divergently selected on tonic immobility duration, a behavioural index of fear. These two lines differ in their behavioural response to some, but not all, fear-inducing situations. In the present study, we investigated the contribution of human intervention in the differentiation between the two lines. To do this, fear responses towards a novel object were compared between lines in three conditions: (1) in the home cage without any human intervention, (2) in the home cage after human handling and (3) after placement in a novel environment by human handling. Fear behaviour differed between lines after human handling, with or without placement in a novel environment, but presentation of a novel object in the home cage without any human intervention induced similar fear responses in the two lines of quail. These results lead us to suggest that in quail, human intervention evokes a dimension of fear that differs from that evoked by sudden presentation of a novel object, in that these two dimensions may be selected independently. 相似文献
5.
《Journal of biological education》2012,46(4):169-172
This paper describes a simple class experiment to investigate the fixation of C02 in the dark and the unique diurnal rhythm of acid production in plants that exhibit Crassulacean Acid Metabolism. Suggestions for additional experiments are also included. 相似文献
6.
F. C. Forster 《Primates; journal of primatology》1995,36(4):501-514
In this paper I examine exploratory behavior and learning in two groups of common marmosets (Callithrix jacchus jacchus), both living under laboratory conditions. The main aim of my studies was to compare behavior occurring in an experimental
testing situation with home-cage behavior, and to assess conditions under which exploration is enhanced. One group of marmosets
was tested individually in an experimental room away from a larger animal holding room, and a second group was observed in
their own home cages, surrounded by other marmosets. Marmosets in both groups were given the opportunity to learn simple tasks,
such as pressing a lever for food or jumping on to a wire grid to open a door and see a neighbouring marmoset, and were provided
with sets of novel or familiar objects to encourage play and exploration. In the isolated experimental cage, marmosets which
learnt a lever-pressing task showed higher general activity levels than controls; in the home cages the mere addition of novel
objects resulted in enhancements in exploratory behavior (measured in terms of contacts with the objects). Although the activities
associated with learning tended to decline over time, the novel objects remained a constant interest throughout the experiment.
The results have implications for maintaining marmosets in captivity, especially in situations when they are housed separately. 相似文献
7.
Estate Sokhadze Joshua Baruth Allan Tasman Lonnie Sears Grace Mathai Ayman El-Baz Manuel F. Casanova 《Applied psychophysiology and biofeedback》2009,34(1):37-51
To better understand visual processing abnormalities in autism we studied the attention orienting related frontal event potentials
(ERP) and the sustained attention related centro-parietal ERPs in a three stimulus oddball experiment. The three stimulus
oddball paradigm was aimed to test the hypothesis that individuals with autism abnormally orient their attention to novel
distracters as compared to controls. A dense-array 128 channel EGI electroencephalographic (EEG) system was used on 11 high-functioning
children and young adults with autism spectrum disorder (ASD) and 11 age-matched, typically developing control subjects. Patients
with ASD showed slower reaction times but did not differ in response accuracy. At the anterior (frontal) topography the ASD
group showed significantly higher amplitudes and longer latencies of early ERP components (e.g., P100, N100) to novel distracter
stimuli in both hemispheres. The ASD group also showed prolonged latencies of late ERP components (e.g., P2a, N200, P3a) to
novel distracter stimuli in both hemispheres. However, differences were more profound in the right hemisphere for both early
and late ERP components. Our results indicate augmented and prolonged early frontal potentials and a delayed P3a component
to novel stimuli, which suggest low selectivity in pre-processing and later-stage under-activation of integrative regions
in the prefrontal cortices. Also, at the posterior (centro-parietal) topography the ASD group showed significantly prolonged
N100 latencies and reduced amplitudes of the N2b component to target stimuli. In addition, the latency of the P3b component
was prolonged to novel distracters in the ASD group. In general, the autistic group showed prolonged latencies to novel stimuli
especially in the right hemisphere. These results suggest that individuals with autism over-process information needed for
the successful differentiation of target and novel stimuli. We propose the potential application of ERP evaluations in a novelty
task as outcome measurements in the biobehavioral treatment (e.g., EEG biofeedback, TMS) of autism. 相似文献
8.
Günter Theißen 《Theorie in den Biowissenschaften》2009,128(1):43-51
Since 150 years it is hypothesized now that evolution always proceeds in a countless number of very small steps (Darwin in
On the origin of species by means of natural selection or the preservation of favoured races in the struggle of life, Murray,
London, 1859), a view termed “gradualism”. Few contemporary biologists will doubt that gradualism reflects the most frequent mode of evolution,
but whether it is the only one remains controversial. It has been suggested that in some cases profound (“saltational”) changes
may have occurred within one or a few generations of organisms. Organisms with a profound mutant phenotype that have the potential
to establish a new evolutionary lineage have been termed “hopeful monsters”. Recently I have reviewed the concept of hopeful
monsters in this journal mainly from a historical perspective, and provided some evidence for their past and present existence.
Here I provide a brief update on data and discussions supporting the view that hopeful monsters and saltational evolution
are valuable biological concepts. I suggest that far from being mutually exclusive scenarios, both gradual and saltational
evolution are required to explain the complexity and diversity of life on earth. In my view, gradual changes represent the
usual mode of evolution, but are unlikely to be able to explain all key innovations and changes in body plans. Saltational
changes involving hopeful monsters are probably very exceptional events, but since they have the potential to establish profound
novelties sometimes facilitating adaptive radiations, they are of quite some importance, even if they would occur in any evolutionary
lineage less than once in a million years. From that point of view saltational changes are not more bizarre scenarios of evolutionary
change than whole genome duplications, endosymbiosis or impacts of meteorites. In conclusion I argue that the complete dismissal
of saltational evolution is a major historical error of evolutionary biology tracing back to Darwin that needs to be rectified. 相似文献
9.
Stephane Gaskin Marilyn Tardif Emily Cole Pavel Piterkin Lima Kayello Dave G. Mumby 《Behavioural processes》2010,83(1):61-17728
We investigated whether object familiarization was related to novel-object preference in the novel-object preference (NOP) test in rats. In Experiment 1, we found that no significant correlation existed between the time spent investigating 2 identical copies of a sample object and the degree of preference for a novel object. In Experiment 2, rats investigated 2 identical sample objects for a total of 5, 30, 60, 90 or 120 s. Investigatory preference for the novel object was compared to chance expectancy as well as between the groups. Only the 90-s group and the 120-s group displayed above-chance investigatory preference for the novel object, but novel-object preference for these 2 groups did not differ from each other, suggesting that a minimal amount of sample object investigation is necessary for rats to develop a novel-object preference, beyond which no increase in novel-object preference was found. In Experiments 3 and 4, normal rats and rats with hippocampal lesions were given repeated test trials, with the same sample object presented with a different novel object, at 24-h and (Experiment 3) and 35-s intervals (Experiment 4). In both experiments, novel-object preference did not increase in magnitude with repeated sample object exposures, suggesting that increased familiarity with the sample object does not result in increased novel-object preference. Rats with lesions of the dorsal hippocampus showed an unreliable investigatory preference for the novel object. These results are discussed in terms of the potential limitations of the NOP test as a tool for the assessment of object-recognition memory in rats. 相似文献
10.
ngel A. Caputi María E. Castell Pedro A. Aguilera Carolina Pereira Javier Nogueira Alejo Rodríguez-Cattaneo Carolina Lezcano 《Journal of Physiology》2008,102(4-6):256
Weakly electric fishes “electrically illuminate” the environment in two forms: pulse fishes emit a succession of discrete electric discharges while wave fishes emit a continuous wave. These strategies are present in both taxonomic groups of weakly electric fishes, mormyrids and gymnotids. As a consequence one can distinguish four major types of active electrosensory strategies evolving in parallel. Pulse gymnotids have an electrolocating strategy common with pulse mormyrids, but brains of pulse and wave gymnotids are alike. The beating strategy associated to other differences in the electrogenic system and electrosensory responses suggests that similar hardware might work in a different mode for processing actively generated electrosensory images. In this review we summarize our findings in pulse gymnotids’ active electroreception and outline a primary agenda for the next research. 相似文献