排序方式: 共有13条查询结果,搜索用时 15 毫秒
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目的:探讨脊髓损伤(SCI)并发下肢痉挛患者经电针刺激联合局部振动治疗后的临床效果。方法:选取本院于2018年1月到2019年6月期间收治的SCI并发下肢痉挛患者90例,根据乱数表法将上述患者分为对照组(n=45)和研究组(n=45),对照组患者给予常规康复系统疗法治疗,研究组在对照组的基础上给予电针刺激联合局部振动治疗,比较两组患者临床疗效、相关量表评分、内收肌角、直腿抬高角以及血清BDNF、PDGF水平。结果:研究组治疗后的临床总有效率为91.11%(41/45),高于对照组的64.44%(29/45)(P0.05)。两组患者治疗后改良Barthel指数、血清BDNF、PDGF水平均升高,且研究组高于对照组(P0.05);改良Ashworth量表、临床痉挛指数评分降低,且研究组低于对照组(P0.05)。两组患者治疗后内收肌角、直腿抬高角均扩大,且研究组大于对照组(P0.05)。结论:电针刺激联合局部振动治疗SCI并发下肢痉挛患者,可有效促进患者康复,改善下肢痉挛,提高生活自理能力,同时还可有效改善血清BDNF、PDGF水平。 相似文献
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目的:观察电针结合红外线照射对反复着床失败(RIF)患者子宫内膜容受性、胚胎移植及妊娠情况的影响。方法:选取102例于2015年5月-2018年5月在我院行复苏胚胎移植的RIF患者,按照随机数字表法将患者分为电针结合红外线照射治疗组(A组,38例)、安慰针刺组(B组,34例)及空白对照组(C组,30例)。比较三组治疗前后血清雌二醇、孕酮水平,于治疗前后检测子宫内膜容受性超声学指标,包括子宫内膜厚度、内膜容积、血管血流指数(VFI)、内膜血流指数(FI)、阻力指数(RI),比较三组胚胎移植及妊娠情况。结果:三组治疗前后血清雌二醇、孕酮水平比较无统计学差异(P0.05)。治疗后A组子宫内膜厚度、内膜容积大于治疗前及B组、C组,VFI、FI高于治疗前及B组、C组,RI低于治疗前及B组、C组(P0.05)。三组移植胚胎数、生化妊娠率、临床妊娠率比较无统计学差异(P0.05),A组胚胎着床率高于B组、C组(P0.05)。结论:电针结合红外线照射治疗RIF患者可以改善子宫内膜容受性,提高胚胎着床率。 相似文献
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戴琪萍裘敏蕾袁晓静陈永强邵萍 《现代生物医学进展》2011,11(19):3655-3657
目的:通过临床研究探讨电针治疗膝关节骨性关节炎的最佳参数,为临床提供更加规范性的治疗,进一步提高电针疗效。方法:将符合膝关节骨性关节炎诊断标准的73例单膝患者随机分为电针疏波组、密波组两组,均针刺患侧膝眼穴,疏波组接2Hz连续波治疗,密波组接40Hz连续波治疗,采用WOMAC评分对两组治疗后疼痛、僵硬、躯体功能进行评估,同时判断1个疗程及3个疗程治疗效果。结果:经统计学处理,完成第一疗程后,两组疼痛评分比较,P均<0.01,说明两组在疼痛疗效上存在差异。而两组僵硬和躯体功能评分的比较,P>0.05,显示两组没有统计学意义。第3疗程后,两组WOMAC总分比较,P均<0.01,具有极显著性差异,第3疗程症状积分低于第1疗程,说明第3疗程后症状改善优于第1疗程。结论:电针疏波组在改善疼痛上优于密波组;第3疗程后,总体症状改善情况优于第1疗程。 相似文献
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Plasma cortisol and beta-endorphin in horses subjected to electro-acupuncture for cutaneous analgesia 总被引:2,自引:0,他引:2
Electro-acupuncture (EA) treatment of horses to induce cutaneous analgesia also increased plasma concentrations of beta-endorphin (beta-EP) and cortisol. The magnitude of these increases did not relate consistently to the degree of EA-induced analgesia. Respiration and heart rates were also markedly increased during EA treatment. Intact female horses had higher packed cell volume and plasma beta-EP as well as lower plasma total protein than castrated male horses. Plasma cortisol, heart rate, and respiration rate did not differ significantly between sexes. None of the parameters measured before or during EA treatment provided an explanation for the differential cutaneous analgesia which depended on sex of subject and locus of stimulation as reported elsewhere. 相似文献
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目的:研究电针对于SAMP8模型小鼠海马区早老蛋白1(presenilian 1,PS1)表达的影响,探讨电针治疗阿尔兹海默病(AD)的作用机制。方法:将20只SAMP8小鼠(早老化小鼠)随机分为模型对照组、电针治疗组,每组10只;10只SAMR1小鼠(正常老化小鼠)组成正常对照组。正常对照组和模型对照组正常饲养15天,在电针治疗组治疗时抓取束缚一次,不做任何治疗;电针治疗组每天治疗前抓取束缚之后再进行电针治疗,治疗穴位选取"百会"、"印堂"、"人中"三穴,频率2 Hz,电流强度以小鼠头部微颤为宜,留针20 min,每日1次,共15天。电针治疗结束后,通过Morris水迷宫实验观察小鼠的行为学变化;通过免疫组化观察SAMP8小鼠海马区PS1蛋白表达情况;通过Western blot方法检测各组海马区的PS1蛋白表达水平。结果:行为学中Morris水迷宫检测显示:模型组与正常对照组比较逃避潜伏时增加,空间探索实验穿越平台次数和平台象限游泳时间明显减少(P0.05,P0.01);电针治疗组逃避潜伏时明显减少,空间探索实验穿越平台次数和平台象限游泳时间明显增加(P0.05);免疫组化观察各组海马区PS1蛋白表达,电针治疗组较模型组明显降低;Western blot结果显示PS1蛋白在海马区表达水平,模型组高于正常对照组(P0.01),而电针治疗组低于模型组(P0.01)。结论:电针可以改善小鼠的学习记忆能力,而且电针治疗组海马区PS1蛋白含量明显低于模型组,电针治疗可能参与减弱PS1蛋白的表达,降低Aβ水平,对于AD治疗有益。 相似文献
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While electro-acupuncture (EA) has been well known to contribute towards neuroplasticity occurring in both the central and
the peripheral nervous system after injury, the underlying mechanism remains largely unknown. This study evaluated the effects
and the possible mechanism of EA on neuronal apoptosis in the spinal cords of cats subjected to the removal of L1–L5 and L7–S2 dorsal root ganglion, sparing the L6 dorsal root ganglion. EA treatment decreased the number of TUNEL-positive apoptotic cells in lamina II of the L3 and L6 cord segments at 7 and 14 days post operation (dpo). This EA-mediated neuroprotection is associated with a decrease in the
number of Bax immunoreactive neurons and an increase in the number of Bcl-2 immunoreactive neurons. Furthermore, Western blot
and RT-PCR analysis revealed a significant downregulation of Bax protein and its mRNA, but an upregulation of Bcl-2 in the
dorsal horn of L3 and L6 cords at both 7 and 14 dpo. The present findings suggest that EA could inhibit neuronal apoptosis in dorsal root deafferentated
cat spinal cords, possibly by Bax downregulation and Bcl-2 upregulation.
Wei Zhao and Qi Zhao contributed equally to this work. 相似文献
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目的探讨电针对短暂性局灶性脑缺血再灌注损伤区神经元谷氨酸受体-2(GluR-2)表达的影响及其意义。方法手术制作中动脉栓塞(MCAO)大鼠模型;应用免疫组织化学方法检测海马CA1区GluR-2的定位表达,并应用免疫印迹(Western blot)方法对其进行定量分析。结果免疫组化结果:正常组、假手术组大鼠海马CA1区GluR-2的阳性反应强度无明显差别(P>0.05);MCAO模型组大鼠海马CA1区GluR-2的阳性反应比正常组和假手术组明显减弱(P<0.05);电针 MCAO模型组海马CA1区GluR-2的阳性反应比手术组明显增强,但比正常组和假手术组仍显偏弱(P<0.05)。Western blot结果与免疫组化结果一致。结论本试验的结果提示电针针刺可上调GluR-2的表达,从而对神经元起到一定保护作用。 相似文献
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Our previous study showed that a cardioprotective effect was produced by pretreatment with acupuncture at bilateral Neiguan acupoints (PC6) and the effect of EA was diminished by propranolol, a nonspecific antagonist of beta-adrenoceptors (beta-ARs) which are the most powerful cardiac receptors, indicating an involvement of beta-ARs. The present study explored further the signaling mechanism underlying the cardioprotective effect of acupuncture pretreatment in rats subjected to myocardial ischemia and reperfusion (MIR). Myocardial ischemia was achieved by ligating the left anterior descending coronary artery and reperfusion by releasing the ligation. Adult rats were divided into three groups, namely, a normal control (NC) group, a group subjected to ischemia and reperfusion (IR) only, and a group given electro-acupuncture (EA) before IR. For EA, bilateral Neiguan points (PC6) of the rats were stimulated for 30 min once a day for 3 consecutive days. The ST segment of ECG, the ratio of infarct size over risk zone, and the contents of beta(1)-adrenoceptor (beta(1)-AR), Gsalpha protein and cAMP in ischemic myocardium were compared among the three groups. IR increased the elevation of ECG ST segment, myocardial infarct size, contents of beta(1)-AR, Gsalpha protein and cAMP. These effects were attenuated by EA pretreatment at bilateral Neiguan acupoints. In conclusion, the present results indicate that EA produces cardioprotective effect against IR which may be mediated via the beta(1)-AR-Gs-protein-cAMP pathway. 相似文献