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Richard F. Jones William A. Prass Charles M. McGrath 《Biochemical and biophysical research communications》1980,97(3):1241-1248
The casein gene content of mouse mammary tumor virus-induced mammary tumors was found to be elevated, apparently in proportion to the increase in MTV proviral copy number. Conversely, mammotropic hormone-induced mammary tumor DNA was deficient in casein genes in 2 of 3 tumors. Globin gene abundance, however, in both normal and malignant mammary tissues was unchanged, regardless of changes in casein gene content. These results suggest that perturbations have occurred in a common region of DNA from mammary tumors with 2 different etiologies. 相似文献
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