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Sano Ayako Nishimura Kazuko Horie Yoshikazu Franco Marcello Mendes Rinaldo Poncio Coelho Kunie Iabuki Rabello Scapolio Silvia Helena Barbin Fukushima Kazutaka dè Camargo Zoilo Pires Miyaji Makoto Montenegro Mario Rubens 《Mycopathologia》1997,138(1):37-41
We compared the antigenic characteristics of two thermo-dependent dimorphic fungi isolated from soil in Botucatu, an endemic
area of paracoccidioidomycosis (PCM) and Paracoccidioides brasiliensis. The soil isolates grew as cerebriform colonies at
37 °C (yeast form) and as cottonous colonies at 25 °C (mycelial form). No pathogenicity for ddY mice or hamsters were observed.
In immunodiffusion test, there were precipitation bands between the 2 soil isolates and pooled PCM patient sera. There were
also common precipitation bands at 21, 50 and 58 kDa between the soil isolates antigens and PCM patient sera by Western-blotting,
but no gp43 kDa band. No gene for gp 43 kDa protein was detected in the soil isolates by PCR. The fact that these isolates
were obtained from an endemic area of PCM and there were some antigenic similarities between the soil isolates and P. brasiliensis
in immunodiffusion test and Western-blotting may have some importance in epidemiological surveys done with paracoccidioidin
as well interfering with the immune response of the exposed population.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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