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Modrý David Koudela Břetislav Al-Oran Ratib M. Amr Zuhair S. Doležel David 《Systematic parasitology》1998,39(1):45-48
Faecal samples from 17 fan-footed geckoes Ptyodactylus puiseuxi Boutan were examined for coccidian parasites. Five geckoes (29%) were found to be passing oöcysts of the genus Isospora Schneider. Comparison with other members of the genus Isospora indicates that the coccidian found represents a new species. Sporulated oöcysts of I. ptyodactyli n. sp. are spherical or subspherical, 22.1 (19.0–24.0) × 21.2 (18.0–23.0) µm, with a shape-index (length/width) of 1.04; and a smooth and bilayered oöcyst wall, 1.0–1.5 µm thick. A micropyle, oöcyst residuum and polar granule are absent. The sporocysts are ellipsoidal, 12.2 (11.0–14.0) × 8.0 (7.5–9.0) µm, with a shape index of 1.5 (1.4–1.9). Stieda and substieda bodies are present, the Stieda body being knob-like and the substieda body spherical to subspherical. A sporocyst residuum is present and composed of numerous granules of different size scattered among the sporozoites. The sporozoites are vermiform, with a slightly granulated surface appearance, and are arranged head to tail within the sporocyst. Most oöcysts have still to sporulate when excreted; sporulation was completed within 12 h at 25 °C. Endogenous development occurs inside the nuclei of enterocytes in the small intestine. 相似文献
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O. Ratib M. Lord M. Becker M. Viallon J.-P. Vallée P. Loubeyre J.-P. Willi O. Rager V. Garibotto H. Zaidi E. Fleury A. Figueiral C. Becker 《Médecine Nucléaire》2012,36(10):605-614
This paper reports the results of a preliminary study evaluating the feasibility and performance of a first whole body hybrid PET/MR scanner allowing sequential acquisition of co-registered MR and PET images. Sixty-two patients underwent whole body PET/MR imaging immediately after a clinical PET/CT. The hybrid device consists of a 3T MR and a time-of-flight PET scanner sharing a single bed allowing sequential acquisition of co-registered MR and PET images. Imaging protocols included a whole body MR used for attenuation correction of PET followed by high-resolution diagnostic MR. Image analysis included visual identification of radiotracer uptake in tumors and measurement of standardized uptake values (SUV) in tumoral lesions and in normal organs. PET images acquired in the PET/MR with a delay of 85 ± 22 minutes (range 49–120 minutes) showed perfect correlation and identical diagnostic quality compared to PET/CT. In 42 patients (68%), additional high-resolution MR sequences were acquired for clinical diagnosis showing excellent quality without any visually detectable artifacts. SUV measurements of tumor lesions obtained after correction with MR attenuation maps showed an excellent correlation with PET/CT (R2 = 0.89 and R2 = 0.95 for mean and maximum tissue uptake respectively). Due to the delay between the two studies, changes in tracer uptake biodistribution of normal tissue were observed. Our preliminary data show that whole body PET/MR is clinically applicable in oncologic patients yielding a comparable diagnostic performance as PET/CT with respect to lesion detection and localization. 相似文献
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Bruno Delobel Ratib Djlelati Odette Gabriel-Robez Marie-Françoise Croquette Roselyne Rousseaux-Prévost Jean Rousseaux Jean-Marc Rigot Y. Rumpler 《Human genetics》1998,102(1):98-102
An apparently balanced reciprocal translocation 46,X,t(Y;6) (q11.23 ∼ q12;p11.1) was observed in an infertile man with severe
oligozooteratozoospermia. Different mitotic chromosome banding patterns were performed and fluorescence in situ hybridization
indicated a breakpoint in the fluorescent Yq heterochromatin. Molecular genetic deletion experiments for the azoospermia factor
region in distal Yq11 showed the retention of the DAZ gene and meiotic pairing configurations suggested that the man’s infertility
could be due to the pairing behaviour of the Y;6 translocation chromosome with the X chromosome visualised by synaptonemal
complex analysis at the electron microscopy level. The morphological appearance of the normal chromosome 6 and the Y;6 translocated
chromosome included in the compartment of the sex vesicle may allow an explanation of the degeneration of most spermatocytes
after the pachytene stage.
Received: 1 August 1997 / Accepted: 25 September 1997 相似文献
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V. Garibotto C. Tabouret-Viaud O. Rager S. Vulliemoz B. Delattre S. Haller M. Wissmeyer M. Seeck K.O. Lovblad H. Zaidi G. Gold O. Ratib D. Zekry M.I. Vargas 《Médecine Nucléaire》2013,37(10-11):561-566
The hybrid Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) is a newly available imaging modality combining the molecular and metabolic PET information with the morphological and functional data provided by MRI. Integrated PET/MRI tomographs were conceived in analogy to the current PET/Computed Tomography (PET/CT) technology, with specific properties linked to the intrinsic differences of MRI and CT imaging. In the field of neuro-imaging, in particular, MRI provides a larger panel of information, as compared with CT, and is already systematically fused and used as a support for PET images for diagnostic and research purposes. We summarize here our current experience with the first integrated PET/MRI tomograph installed in Switzerland, concerning specifically three clinical applications: brain tumors characterization, the diagnosis of neurodegenerative dementias and the presurgical evaluation of pharmaco-resistant epilepsy. With this sequential tomograph, we could combine the full range of diagnostic MR sequences (including diffusion tensor imaging, tractography, spectroscopy, functional MR) with PET imaging of brain glucose metabolism (by 18F-Fluorodeoxyglucose–FDG) and of amino acid transport (by 18F-Fluoroethyltyrosine–FET). We also summarize the main results obtained in neuro-imaging by the different groups working with these new hybrid tomographs. These data show that PET/MRI, acquired in a single imaging session, may represent the modality of choice for neuro-imaging. 相似文献
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B. Brun R. Djlelati Y. Rumpler C. Koehl M. Fabre 《Primates; journal of primatology》2001,42(4):281-290
A comparative ultrastructural study of the seminiferous epithelium was conducted during the mating and non-mating seasons
of twoEulemur species:E. fulvus andE. macaco. The ultrastructure of the junctional complexes of the Sertoli cells, and the modifications in the spermatids during spermiogenesis
are reported. Acridine orange staining of the sperm cells of these animals showed that the chromatin compaction was complete
in all spermatozoa. 相似文献
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