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排序方式: 共有148条查询结果,搜索用时 437 毫秒
1.
V. D. Lakhno A. S. Shigaev T. B. Feldman V. A. Nadtochenko M. A. Ostrovsky 《Doklady. Biochemistry and biophysics》2016,471(1):435-439
A quantum-classical model of photoisomerization of the visual pigment rhodopsin chromophore is proposed. At certain (and more realistic) parameter value combinations, the model is shown to accurately reproduce a number of independent experimental data on the photoreaction dynamics: the quantum yield, the time to reach the point of conical intersection of potential energy surfaces, the termination time of the evolution of quantum subsystem, as well as the characteristic low frequencies of retinal molecular lattice fluctuations during photoisomerization. In addition, the model behavior is in good accordance with experimental data about coherence and local character of quantum transition. 相似文献
2.
K. M. Serova A. E. Vishnyakov O. V. Zaitseva O. N. Kotenko A. N. Ostrovsky 《Doklady biological sciences》2017,475(1):144-147
The nervous system structure was compared for the first time in avicularia and vibracula in seven species of the cheilostome bryozoans from six families by immunohistochemical methods and confocal scanning microscopy. Regardless of significant differences in heterozooid shape, size, and position in a colony, their muscular and nervous systems have a common structure, which suggests their parallel evolution. 相似文献
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Biology Bulletin - A review of our own data and published material on the screening pigments of the eyes of vertebrates and invertebrates and the human eye, i.e., melanosomes and ommochromes, is... 相似文献
5.
Tatiana B. Feldman Oleksandr I. Ivankov Alexander I. Kuklin Tatiana N. Murugova Marina A. Yakovleva Olga A. Smitienko Irina B. Kolchugina Adam Round Valentin I. Gordeliy Alexander V. Belushkin Mikhail A. Ostrovsky 《生物化学与生物物理学报:生物膜》2019,1861(10):183000
The supramolecular organization of the visual pigment rhodopsin in the photoreceptor membrane remains contentious. Specifically, whether this G protein-coupled receptor functions as a monomer or dimer remains unknown, as does the presence or absence of ordered packing of rhodopsin molecules in the photoreceptor membrane. Completely opposite opinions have been expressed on both issues. Herein, using small-angle neutron and X-ray scattering approaches, we performed a comparative analysis of the structural characteristics of the photoreceptor membrane samples in buffer, both in the outer segment of photoreceptor cells, and in the free photoreceptor disks. The average distance between the centers of two neighboring rhodopsin molecules was found to be ~5.8 nm in both cases. The results indicate an unusually high packing density of rhodopsin molecules in the photoreceptor membrane, but molecules appear to be randomly distributed in the membrane without any regular ordering. 相似文献
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T. B. Feldman O. I. Ivankov T. N. Murugova A. I. Kuklin P. V. Shelyakin M. A. Yakovleva V. I. Gordeliy A. V. Belushkin M. A. Ostrovsky 《Doklady. Biochemistry and biophysics》2015,465(1):420-423
Supramolecular organization of rhodopsin in the photoreceptor membrane was investigated by small-angle neutron scattering method. The experiments, which were performed with mixtures of heavy/light water as solvent (contrast variation method), were aimed at obtaining information about the lipid and protein components of the photoreceptor disc membrane separately. It was shown that the packaging density of the rhodopsin molecules in the photoreceptor membrane was unusually high: the distance between the centers of the molecules was approximately 56 Å. The probability of the monomeric state of rhodopsin molecules in the photoreceptor membrane, according to the data obtained, is rather high. 相似文献
8.
D. A. Dolgikh A. Yu. Malyshev S. V. Salozhin O. V. Nekrasova L. E. Petrovskaya M. V. Roshchin A. A. Borodinova T. B. Feldman P. M. Balaban M. P. Kirpichnikov M. A. Ostrovsky 《Doklady. Biochemistry and biophysics》2015,465(1):424-427
Anionic channelrhodopsin slow ChloC was expressed in the culture of nerve cells and in vivo in mouse brain. We demonstrated ability of slow ChloC to suppress effectively the activity of the neuron in response to the illumination with the visible light. It has been shown for a first time that slow ChloC works equally efficiently in both neuronal culture and in the whole brain being expressed in vivo. Thus, slow ChloC could be considered as an effective optogenetic tool capable in response to light stimulation to inhibit the generation of action potentials in the neuron. 相似文献
9.
A. E. Abu Khamidakh J. V. Demchuk P. P. Zak M. Lindström M. A. Ostrovsky 《Moscow University Biological Sciences Bulletin》2010,65(2):51-55
Microspectrophotometric measurements of screening granules in Mysis relicta eyes showed that most of the granules have xanthommatin spectra (7nmax 455 nm) with selective absorption of blue light. We calculated spectral sensitivity of M.relicta eyes using screening granules absorption spectra and visual pigment absorption spectra. According to our computations the
calculated spectral sensitivity curve appears to be in a good correspondence with the real spectral sensitivity. 相似文献
10.
Studies of molecular mechanisms of chaperone-like activity of -crystallin became an active field of research over last years. However, fine interactions between -crystallin and the damaged protein and their complex organization remain largely uncovered. Complexation between - and L-crystallins was studied during thermal denaturation of L-crystallin at 60°C using small-angle X-ray scattering (SAXS), light scattering, gel-permeation chromatography, and electrophoresis. A mixed solution of - and L-crystallins at concentrations about 10 mg/ml incubated at 60°C was found to contain their soluble complexes with a mean radius of gyration 14 nm, mean molecular mass 4 MDa and maximal size over 40 nm. In pure L-crystallin solution, no complexes were observed at 60°C. In SAXS studies, transitions in the -crystallin quaternary structure at 60°C were shown to occur and result in doubling of the molecular weight. This suggests that during the temperature-induced denaturation of L-crystallin it binds with modified -crystallin or, alternatively, L-crystallin complexation and -crystallin modifications are concurrent. Estimates of the -L-crystallin complex size and relative contents of - and -L-crystallins in the complex suggest that several -crystallin molecules are involved in complex formation. 相似文献