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排序方式: 共有102条查询结果,搜索用时 15 毫秒
1.
V P Shelepov G R Pasha-Zade V A Chekulaev V L Moiseev V V Adler 《Biulleten' eksperimental'no? biologii i meditsiny》1987,104(11):612-615
Tumour growth was shown to be associated with DNA breakdown in thymocytes of rats bearing Zajdela ascites hepatomas. The tumour action on the thymus is mediated through adrenal glands since bilateral adrenalectomy completely prevents DNA breakdown in thymocytes. Using Southern hybridization of DNA genome with probes for histone, ribosomal and heat shock gene (hsp 70), it was shown that the degradation products of specific DNA sequences are as heterogenous as those of total DNA, although marked differences in appearance of nucleosomal ladder were seen. These data were interpreted to indicate different patterns of DNA breakdown in dying thymocytes. DNA breakdown in thymocytes in vivo and in isolated rat liver nuclei in vitro seems to proceed by similar mechanisms. 相似文献
2.
A V Itkes M Ia Karpe?ski? O N Kartasheva S N Mikha?lov G P Moiseev 《Molekuliarnaia biologiia》1988,22(5):1393-1398
Phosphodiesterase stability of synthetic analogs of 2',5'-oligoadenylates, the mediators of antiviral and antiproliferative action of interferons was analysed. The analogs with a 3'-terminal acyclic nucleoside residue were prepared. These analogs were treated with NIH3T3 cell lysate, mice liver homogenate and snake venom phosphodiesterase. All analogs have demonstrated a high stability as compared with the natural 2',5'-oligoadenylate and its 3'-deoxyderivative. The possible biological activity of these stable analogs of 2',5'-oligoadenylates is discussed. 相似文献
3.
I I Il'in R Begam E V Mal'tsev I N Moiseev 《Arkhiv anatomii, gistologii i émbriologii》1986,90(2):53-57
Tetrapeptide tuftsin action on the activity of succinate dehydrogenase (SDG), malate dehydrogenase (MDG) and monoamine-oxidase (MAO) in microstructures of the neocortex, hippocampus and hypothalamus (supraoptic and paraventricular nuclei, retrochiasmic zone) has been investigated by means of histochemical methods. Simultaneously, pyruvate-, malate-, glutamate-, alfaketoglutamate-, succinate- and lactate-dehydrogenase activity in the neocortex and in the structures of the limbic system has been studied biochemically. SDG and MDG activity increases in neurons and glycocytes of all the hypothalamic formations mentioned. Changes in the activity of dehydrogenases in the hippocampus and neocortex under the same stimulation are less pronounced. MAO activity also increases in the nerve terminals converging on the bodies and dendrites of hypothalamic neurons and in the preterminal fibers of the neocortex, Tuftsin increases oxidative-reducing processes in various structures of the brain, but at the same time it possesses a predominant influence on the limbic system structures. 相似文献
4.
5.
Belousov A. V. Morozov V. N. Krusanov G. A. Moiseev A. N. Davydov A. S. Shtil A. A. Klimanov V. A. Kolyvanova M. A. Samoylov A. S. 《Biophysics》2020,65(4):541-547
Biophysics - Gold nanoparticles are promising radiosensitizers for proton radiotherapy. However, the physical mechanisms of gold nanoparticles radiosensitization remain unclear. In the present... 相似文献
6.
Moiseev S. A. Ivanov S. M. Gorodnichev R. M. 《Journal of Evolutionary Biochemistry and Physiology》2022,58(2):610-622
Journal of Evolutionary Biochemistry and Physiology - The study considers the synergetic effects manifested at the level of interaction between the various parts of the musculoskeletal system with... 相似文献
7.
A. V. Khrunin F. G. Ivanova A. A. Moiseev V. A. Gorbunova S. A. Limborska 《Russian Journal of Genetics》2011,47(12):1496-1498
The CYP2E1 gene polymorphism has been studied in Yakut women with ovarian cancer and without cancer. The two groups have been found
to substantially differ in the frequency of the CYP2E1*1D allele (with a 96-bp insertion in the promoter region of the gene): it is more frequent in healthy women (16.3 versus 7.4%,
P = 0.007). 相似文献
8.
The review of modern luminescent methods of research, their prospects and potentialities of practical application in biological researches is presented. Special attention is given to the study of dynamics of the processes of peroxide oxidation and to activity of the enzymes of antioxidant protection in biological systems using the chemiluminescent methods, and also to their use in experimental oncology and radiobiology. 相似文献
9.
R. M. Gorodnichev E. A. Pivovarova A. Puhov S. A. Moiseev A. A. Savochin T. R. Moshonkina N. A. Chsherbakova V. A. Kilimnik V. A. Selionov I. B. Kozlovskaya V. R. Edgerton Yu. P. Gerasimenko 《Human physiology》2012,38(2):158-167
A new method for the activation of spinal locomotor networks (SLN) in humans by transcutaneous electrical spinal cord stimulation (tESCS) has been described. The tESCS applied in the region of the T11-T12 vertebrae with a frequency of 5?C40 Hz elicited involuntary step-like movements in healthy subjects with their legs suspended in a gravity-neutral position. The amplitude of evoked step-like movements increased with increasing tESCS frequency. The frequency of evoked step-like movements did not depend on the frequency of tESCS. It was shown that the hip, knee, and ankle joints were involved in the evoked movements. It has been suggested that tESCS activates the SPG (SLN) through in part, via the dorsal roots that enter the spinal cord. tESCS can be used as a noninvasive method in rehabilitation of spinal pathology. 相似文献
10.
V. G. Dvoretsky M. P. Venger P. R. Makarevich D. V. Moiseev 《Russian Journal of Marine Biology》2012,38(1):91-95
The distribution of bacterio- and zooplankton was studied in West Spitsbergen (Svalbard) coastal waters in August 2009. The
bacterial abundance and biomass varied from 110 to 3360 × 103 cells/ml and from 0.66 to 44.93 mg C/m3, respectively. These values were the highest in the surface water layers and decreased with depth. The greatest abundance
of bacteria (5099 individuals/m3) was found in the freshened and warm water layer in Isfjorden. The highest biomass of zooplankton
(182.41 mg C/m3) was registered in the zone of interaction of coastal and transformed Atlantic waters in the archipelago inner shelf. The
spatial variations of abundance and biomass of the planktonic communities were related to the thermohaline characteristics
of the water masses and, probably, to microalgal blooms. 相似文献