排序方式: 共有5条查询结果,搜索用时 140 毫秒
1
1.
Karavidas MK Lehrer PM Vaschillo E Vaschillo B Marin H Buyske S Malinovsky I Radvanski D Hassett A 《Applied psychophysiology and biofeedback》2007,32(1):19-30
Major depressive disorder (MDD) is a common mood disorder that can result in significant discomfort as well as interpersonal and functional disability. A growing body of research indicates that autonomic function is altered in depression, as evidenced by impaired baroreflex sensitivity, changes in heart rate, and reduced heart rate variability (HRV). Decreased vagal activity and increased sympathetic arousal have been proposed as major contributors to the increased risk of cardiovascular mortality in participants with MDD, and baroreflex gain is decreased. STUDY OBJECTIVES: To assess the feasibility of using HRV biofeedback to treat major depression. DESIGN: This was an open-label study in which all eleven participants received the treatment condition. Participants attended 10 weekly sessions. Questionnaires and physiological data were collected in an orientation (baseline) session and Treatment Sessions 1, 4, 7 and 10. MEASUREMENTS AND RESULTS: Significant improvements were noted in the Hamilton Depression Scale (HAM-D) and the Beck Depression Inventory (BDI-II) by Session 4, with concurrent increases in SDNN, standard deviation of normal cardiac interbeat intervals) an electrocardiographic estimate of overall measure of adaptability. SDNN decreased to baseline levels at the end of treatment and at follow-up, but clinically and statistically significant improvement in depression persisted. Main effects for task and session occurred for low frequency range (LF) and SDNN. Increases in these variables also occurred during breathing at one's resonant frequency, which targets baroreflex function and vagus nerve activity, showing that subjects performed the task correctly. CONCLUSIONS: HRV biofeedback appears to be a useful adjunctive treatment for the treatment of MDD, associated with large acute increases in HRV and some chronic increases, suggesting increased cardiovagal activity. It is possible that regular exercise of homeostatic reflexes helps depression even when changes in baseline HRV are smaller. A randomized controlled trial is warranted. 相似文献
2.
3.
Karavidas MK Tsai PS Yucha C McGrady A Lehrer PM 《Applied psychophysiology and biofeedback》2006,31(3):203-216
The clinical presentation of primary Raynaud’s phenomenon (RP) derives from various pathogenic triggers. The use of thermal biofeedback (TBF) may be of benefit in reducing the severity and frequency of attacks. This article summarizes the relevant research regarding the pathophysiology of primary RP and mechanism of TBF for RP. Systematic reviews of the efficacy of TBF for RP and treatment guidelines for clinicians are provided. The panel concludes that the level of evidence for TBF efficacy is categorized as Level IV: efficacious. The rationale, based on three randomized controlled trials conducted in independent laboratories, demonstrated “superiority or equivalence” of treatments that include TBF. However, randomly controlled trials (RCT) with positive clinical outcomes tended to be small. A large RCT with negative results did not effectively teach handwarming skills. Procedures for reviewing and rating of the levels of evidence of efficacy of studies was based on the Template for Developing Guidelines for the Evaluation of the Clinical Efficacy of Psychophysiological Interventions developed by the joint task force of the AAPB and the Society for Neuronal Regulation (SNR). 相似文献
4.
Hassett AL Radvanski DC Vaschillo EG Vaschillo B Sigal LH Karavidas MK Buyske S Lehrer PM 《Applied psychophysiology and biofeedback》2007,32(1):1-10
Fibromyalgia (FM) is a non-inflammatory rheumatologic disorder characterized by musculoskeletal pain, fatigue, depression,
cognitive dysfunction and sleep disturbance. Research suggests that autonomic dysfunction may account for some of the symptomatology
of FM. An open label trial of biofeedback training was conducted to manipulate suboptimal heart rate variability (HRV), a
key marker of autonomic dysfunction. Methods: Twelve women ages 18–60 with FM completed 10 weekly sessions of HRV biofeedback. They were taught to breathe at their resonant
frequency (RF) and asked to practice twice daily. At sessions 1, 10 and 3-month follow-up, physiological and questionnaire
data were collected. Results: There were clinically significant decreases in depression and pain and improvement in functioning from Session 1 to a 3-month
follow-up. For depression, the improvement occurred by Session 10. HRV and blood pressure variability (BPV) increased during
biofeedback tasks. HRV increased from Sessions 1–10, while BPV decreased from Session 1 to the 3 month follow-up. Conclusions: These data suggest that HRV biofeedback may be a useful treatment for FM, perhaps mediated by autonomic changes. While HRV
effects were immediate, blood pressure, baroreflex, and therapeutic effects were delayed. This is consistent with data on
the relationship among stress, HPA axis activity, and brain function. 相似文献
5.
Paul Lehrer Maria Katsamanis Karavidas Shou-En Lu Susette M. Coyle Leo O. Oikawa Marie Macor Steve E. Calvano Stephen F. Lowry 《Applied psychophysiology and biofeedback》2010,35(4):303-315
Exposure of healthy people to lipopolysaccharide (LPS; endotoxin) produces a pro-inflammatory response, subjective symptoms,
and decreased heart rate variability (HRV). Given the efficacy of HRV biofeedback (BF) for treating asthma, the large autonomic
effects of HRV BF, and the link between vagus nerve activity and inflammation, we hypothesized that HRV BF would dampen the
acute manifestations of systemic inflammation induced by LPS challenge. Healthy participants age 18-40 were randomly assigned
to four-one-hour training sessions of either HRV BF (n = 6) or a control 15/min paced breathing condition (n = 5) prior to acute experimentally induced LPS exposure. Participants were coached to do the procedures for 10 min each at
five hourly time points after LPS injection, and then 2 h later. Subjective symptoms, HRV parameters, and plasma cytokine
levels were measured at each time point, 2 h afterward, and the following morning. Participants were able to perform the procedures
both during four pre-exposure training sessions and while experiencing LPS-induced symptoms. The HRV BF group showed significant
attenuation of the LPS-induced decline in HRV for the 6 h following LPS exposure, suggesting that HRV BF decreased autonomic
dysfunction produced by LPS-induced inflammation. HRV BF also reduced symptoms of headache and eye sensitivity to light, but
did not affect LPS-induced levels of pro-inflammatory cytokines or symptoms of nausea, muscle aches, or feverishness. Further
evaluation of HRV BF appears to be warranted among patients with inflammatory conditions. 相似文献
1