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Jirapast Sichaem Thammarat Aree Suttira Khumkratok Jonkolnee Jong-aramruang Santi Tip-pyang 《Phytochemistry letters》2012,5(3):665-667
A new apotirucallane, trichostemonate (1), was isolated from the roots of Walsura trichostemon. The complete structural assignment of this new compound was elucidated from spectroscopic methods and the stereochemistry of 1 was confirmed by X-ray crystallographic analysis. Moreover, this new compound was evaluated for its cytotoxicity (KB and HeLa cells), and showed significant cytotoxicity against both KB and HeLa cell lines with IC50 values of 3.28 and 0.93 μg/mL, respectively. 相似文献
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Phuwapraisirisan P Puksasook T Jong-Aramruang J Kokpol U 《Bioorganic & medicinal chemistry letters》2008,18(18):4956-4958
A series of phenylethyl cinnamides, which included new compounds named anhydromarmeline, aegelinosides A and B, were isolated from Aegle marmelos leaves as alpha-glucosidase inhibitors. The structures of new compounds were characterized by spectroscopic data and chemical degradation. Of compounds isolated, anhydroaegeline revealed the most potent inhibitory effect against alpha-glucosidase with IC(50) value of 35.8 microM. The present result also supports ethnopharmacological use of A. marmelos as a remedy for diabetes mellitus. 相似文献
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