Sleep spindle characteristics in overweight adolescents with obstructive sleep apnea syndrome

Sleep and Biological Rhythms - Sleep spindles may display a sleep protective function. Thus, their activity is also a stable marker of sleep disturbances. We investigated whether spindle activity...     

Effect of acetylcholine on phosphorylase from skeletal muscle]

Acetylcholine (1-10(-5) g/ml) was shown to increase the content of active form of phosphorylase A in homogenate of cat skeletal muscle. Atropine (1-10(-5) g/ml) diminished acetylcholine-induced increase in the phosphorylase activity from 22% to 5.28%. Activating effect of acetylcholine was observed also in superatant (105000 g), although it was 2-fold decreased. No acetylcholine-induced phosphorylase activation was observed in the presence of Mg2+. Addition of Ca2+ (2.2-10(-14) M) did not affect considerably the activation process. It is concluded that the mechanism of acetylcholine-induced phosphorylase activation is different from the effect of adrenaline on phosphorylase.     

Alteration of sleep homeostasis and cognitive impairment in apneic obese adolescents

Sleep and Biological Rhythms - To evaluate specific features of sleep pattern and neurocognitive performance in OSA obese adolescents to correlate sleep macrostructural parameters and phasic events...