On blocking rules for the bootstrap with dependent data

We address the issue of optimal block choice in applicationsof the block bootstrap to dependent data. It is shown that optimalblock size depends significantly on context, being equal ton^1/3, n^1/4 and n^1/5 in the cases of variance or bias estimation,estimation of a onesided distribution function, and estimationof a two-sided distribution function, respectively. A clearintuitive explanation of this phenomenon is given, togetherwith outlines of theoretical arguments in specific cases. Itis shown that these orders of magnitude of block sizes can beused to produce a simple, practical rule for selecting blocksize empirically. That technique is explored numerically.     

背部烫伤大鼠脑及肝脏热休克蛋白70（hsp70）mRNA的诱导

本文首先用α－＾３２Ｐ标记的热休克蛋白７０（ｈｓｐ７０）ｃＤＮＡ为探针,研究了背部烫伤对大鼠脑肝ｈｓｐ７０ｍＲＮＡ的诱导。结果表明,烫伤大鼠脑肝ｈｓｐ７０ｍＲＮＡ的表达明显增加,烫伤后５ｍｉｎ内开始出现,２４ｈ后恢复正常。由于烫伤后脑肝温度的增加不超过１℃。因此温度升高不大可能是该基因表达增加的原因。在此基础上用ｈｓｐ７０的抗体,采用Ｗｅｓｔｅｒｎ ｂｌｏｔ的方法,分析了烫伤大鼠脑肝ｈｓｐ７０的变