Arachidonic acid metabolites and colchicine in Beh?et's disease (BD)

Vasculitis is accepted to be the basis of Beh?et's disease (BD) which is a multisystem disease, and the arachidonic acid(AA) metabolites acting as balancing mediators in the organism are accepted to be responsible for the vasculitis. In this study, we examined the prostaglandin E2 (PGE2) and leukotriene C4 (LTC4) levels of the patients with BD before and after colchicine therapy. We found a statistical decrease in the PGE2 and LTC4 levels after colchicine therapy compared to the previous levels, concluding that colchicine inhibits the inflammation and the polymorphonuclear leukocyte (PML) chemotaxis by inhibiting the cyclooxygenase and lipoxygenase pathways.     

Clearing and embedding in polyester resin for demonstrating the nerve distribution pattern of skeletal muscles

The preservation of many stained gross specimens in solution creates some difficulties. It is convenient and effective to preserve material in polyester resin instead of glycerol. The aim of this study was to determine the usefulness of clearing and embedding using polyester resin. The samples consisted of the nerve distribution patterns of skeletal muscles stained using Sihler's method. The muscles were cleared more successfully and the intramuscular nerve distributions were demonstrated better in polyester than in glycerol. The method presented here eliminates not only the storage and handling problems of specimens, but also problems such as pale stains and the molding of preparations. Furthermore, it is more convenient to examine and to photograph specimens cleared and embedded in polyester than those stored in glycerol.     

Clearing and embedding in polyester resin for demonstrating the nerve distribution pattern of skeletal muscles

The preservation of many stained gross specimens in solution creates some difficulties. It is convenient and effective to preserve material in polyester resin instead of glycerol. The aim of this study was to determine the usefulness of clearing and embedding using polyester resin. The samples consisted of the nerve distribution patterns of skeletal muscles stained using Sihler's method. The muscles were cleared more successfully and the intramuscular nerve distributions were demonstrated better in polyester than in glycerol. The method presented here eliminates not only the storage and handling problems of specimens, but also problems such as pale stains and the molding of preparations. Furthermore, it is more convenient to examine and to photograph specimens cleared and embedded in polyester than those stored in glycerol.     

Clearing and embedding in polyester resin for demonstrating the nerve distribution pattern of skeletal muscles.

The preservation of many stained gross specimens in solution creates some difficulties. It is convenient and effective to preserve material in polyester resin instead of glycerol. The aim of this study was to determine the usefulness of clearing and embedding using polyester resin. The samples consisted of the nerve distribution patterns of skeletal muscles stained using Sihler's method. The muscles were cleared more successfully and the intramuscular nerve distributions were demonstrated better in polyester than in glycerol. The method presented here eliminates not only the storage and handling problems of specimens, but also problems such as pale stains and the molding of preparations. Furthermore, it is more convenient to examine and to photograph specimens cleared and embedded in polyester than those stored in glycerol.     

Examining the microanatomy of various fetal body parts using the orcein-picroindigocarmine staining method

It is difficult to distinguish muscle, vessel, nerve, fascia, tendon and many other structures in fetal sections. The aim of the study reported here was to research the practicability of orcein-picroindigocarmine staining for distinguishing anatomic structures in histological sections containing complex structures. Histological serial sections of hand, foot, head and neck of four 18- to 20-week old fetuses were used. Bone matrix was stained bright blue, collagen fibers tones of green to blue, elastic fibers brown, cartilage matrix tones of pink, and chondroblasts blue. Muscles and erythrocytes were stained yellow to green, epidermis reddish brown, skin appendices including hair and nail stained light yellow to green.     

The incidence of basal sphenoid bony bridges in dried crania and cadavers: their anthropological and clinical relevance

The aim of this study was to investigate the incidence of the pterygospinous and pterygoalar bony bridges and the variations in these bony bridges among Anatolians. A total of 452 adult dry skulls (258 males and 194 females) of the Anatolian population were investigated for both the pterygospinous and the pterygoalar bony bridges. In 80 of the 452 dry skulls (37 male and 43 female), it was possible to inspect the cranial cavity. In these skulls, sellar and sphenopetrous bridges were also investigated. In addition to this, the mandibular nerve of 9 fixed cadavers was carefully dissected and the distribution of its branches was determined on both sides. Complete pterygospinous osseous bridges were found in 5.5% of the samples and complete pterygoalar bridges in 4.9%. In the dry skulls with removed calvaria, complete sellar osseous bridges were found on both sides in 34.2% of specimens, complete pterygospinous bridges in 8.8% and complete pterygoalar bridges in 7.5%. No complete sphenopetrous bridges were found. In the cadaveric study, nerve entrapment due to a pterygoalar ligament on the left side was found in one cadaver. Such variations should be kept in mind in clinical complaints such as mandibular neuralgia, especially during chewing.     

Arachidonic acid metabolites and colchicine in Behçet's disease (BD)

Vasculitis is accepted to be the basis of Behçet's disease (BD) which is a multisystem disease, and the arachidonic acid(AA) metabolites acting as balancing mediators in the organism are accepted to be responsible for the vasculitis.In this study, we examined the prostaglandin E₂ (PGE₂) and leukotriene C₄ (LTC₄) levels of the patients with BD before and after colchicine therapy. We found a statistical decrease in the PGE₂ and LTC₄ levels after colchicine therapy compared to the previous levels, concluding that colchicine inhibits the inflammation and the polymorphonuclear leukocyte (PML) chemotaxis by inhibiting the cyclooxygenase and lipoxygenase patways.