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1.
AN ODOROUS BASIDIOBOLUS OFTEN PRODUCING CONIDIA PLURALLY AND FORMING SOME DICLINOUS SEXUAL APPARATUS
Charles Drechsler 《American journal of botany》1964,51(7):770-777
A coarse fungus isolated from decaying plant detritus originating in northern Wisconsin and western Maryland is newly described as Basidiobolus magnus. Like B. ranarum, it gives off an odor recalling benzene hexachloride. Its mycelium, especially while young, includes many long segments markedly wider in the middle than at the ends. Its distally phototropic conidiophores sometimes are branched in their procumbent or submerged portions, and each propulsive distention may bear 1–3 globose conidia, which may be shot off forcibly or may fall through collapse of the supporting hypha. The primary globose conidia of B. magnus are generally larger than those of B. ranarum, from which they differ further in sometimes giving rise to plural secondary conidia of either the globose or the elongated adhesive type. The zygospores, like those of B. ranarum, show abundantly undulated sculpture but differ in their generally larger size, their occasional origin through conjugation between cells of separate hyphae, their rather frequent binary development, and their germination by production, often, of 2 globose uninucleated conidia. The elongated conidia, which seem generally no bigger than those of B. ranarum and are often only meagerly tipped with adhesive material, sometimes undergo conversion into sporangia through internal segmentation. 相似文献
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Charles Drechsler 《American journal of botany》1963,50(8):839-842
Drechsler , Charles . (USDA, Plant Industry Sta., Beltsville, Md.) A new nematode-destroying hyphomycete of the genus Harposporium. Amer. Jour. Bot. 50(8): 839–842. Illus. 1963.—A mucedinaceous parasite that destroyed a largish nematode in a maize-meal-agar plate culture to which had been added some leaf mold from an oak wood in central Maryland is newly described as Harposporium dicorymbum. It permeates the host animal with colorless septate assimilative hyphae, 2.5-8.5 μ wide, that soon put forth procumbent septate conidiophores bearing mostly subglobose phialides with 1-3 sterigmata. Its very distinctive conidia are composed of a minutely pedicellate globose part, 4-7 μ in diameter, together with a cylindrical outgrowth, 3-9 μ long and 2-3 μ wide, which is furnished distally with a short posterior and a longer anterior beak. 相似文献
3.
Charles Drechsler 《American journal of botany》1960,47(5):368-377
Drechsler , Charles . (Plant Industry Sta., Beltsville, Md.) Two new species of Conidiobolus found in plant detritus. Amer. Jour. Bot. 47(5) : 368—377. Illus. 1960.–By canopying Petri plates of maize-meal agar with small quantities of friable or mealy plant detritus 2 new species of Conidiobolus, both of moderate dimensions, were isolated. They are described as C. incongruus and C. multivagus. The former, obtained from leaf mold collected in Colorado, produces zygospores which with respect to their internal organization differ markedly from those of congeneric species but resemble rather closely the globuliferous zygospores of Basidiobolus haptosporus and B. meristosporus. Conidiobolus multivagus, obtained from decayed twigs of Casuarina equisetifolia gathered in western Florida, forms a mycelium that soon becomes conspicuously disconnected. The disconnected condition here results partly from the production of many detached slender filaments, which, by constantly withdrawing protoplasmic materials from the posterior end while elongating at the tip, migrate through the slated substratum apparently without any intake of nutrients. The detached conidia of C. incongruus are provided with a more prominent basal papilla than those of C. multivagus, though both species show equally sharp demarcation between the globose main contour of the conidium and the dome-shaped contour of the papillia. 相似文献
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Hooper DM Hill H Drechsler WI Morrissey MC 《Journal of strength and conditioning research / National Strength & Conditioning Association》2002,16(3):409-415
The purpose of this study was to examine whether joint angle specificity occurs in open and closed kinetic chain resistance training of the knee extensors after anterior cruciate ligament reconstruction (ACLR). Isokinetic knee extensor strength was measured at 60 and 210 degrees.s(-1) in 32 patients, 2 and 6 weeks after surgery. Between test sessions, patients participated in a 4-week program of injured leg resistance training of the knee extensors in either open kinetic chain (OKC) knee extension or leg press exercises. Isokinetic testing knee range of motion (ROM) was divided into 5 equal portions from flexion to extension, and the mean torque was calculated over those divisions: 0-20%, 20-40%, 40-60%, 60-80%, and 80-100% ROM. Analysis of variance indicated that there were no significant differences between patients in the knee extension or leg press exercise groups. 相似文献
7.
Biological applications of solid-state NMR (SS-NMR) have been predominantly in the area of model membrane systems. Increasingly the focus has been membrane peptides and proteins. SS-NMR is able to provide information about how the peptides or proteins interact with the lipids or other peptides/proteins in the membrane, their effect on the membrane and the location of the peptides or proteins relative to the membrane surface. Recent developments in biological SS-NMR have been made possible by improvements in labelling and NMR techniques. This review discusses aligned systems and magic angle spinning techniques, bilayers and bicelles, and measurement of chemical shift anisotropy and dipolar coupling. A number of specific experiments such as cross polarization, rotational resonance, REDOR, PISEMA, MAOSS and multidimensional experiments are described. In addition to 2H, 13C and 15N, recent solid-sate 1H, 19F and 17O NMR work is discussed. Several examples of the use of SS-NMR to determine the structure of membrane peptides and proteins are given. 相似文献
8.
Helene Hartwig Carlos Silvestre-Roig Jeffrey Hendrikse Linda Beckers Nicole Paulin Kim Van der Heiden Quinte Braster Maik Drechsler Mat J. Daemen Esther Lutgens Oliver Soehnlein 《PloS one》2015,10(10)
Atherosclerosis-associated diseases are the main cause of mortality and morbidity in western societies. The progression of atherosclerosis is a dynamic process evolving from early to advanced lesions that may become rupture-prone vulnerable plaques. Acute coronary syndromes are the clinical manifestation of life-threatening thrombotic events associated with high-risk vulnerable plaques. Hyperlipidemic mouse models have been extensively used in studying the mechanisms controlling initiation and progression of atherosclerosis. However, the understanding of mechanisms leading to atherosclerotic plaque destabilization has been hampered by the lack of proper animal models mimicking this process. Although various mouse models generate atherosclerotic plaques with histological features of human advanced lesions, a consensus model to study atherosclerotic plaque destabilization is still lacking. Hence, we studied the degree and features of plaque vulnerability in different mouse models of atherosclerotic plaque destabilization and find that the model based on the placement of a shear stress modifier in combination with hypercholesterolemia represent with high incidence the most human like lesions compared to the other models. 相似文献
9.
Yoram Nevo Shlomit Aga-Mizrachi Edva Elmakayes Nurit Yanay Keren Ettinger Moran Elbaz Zivia Brunschwig Oshrat Dadush Galit Elad-Sfadia Roni Haklai Yoel Kloog Joab Chapman Shimon Reif 《PloS one》2011,6(3)
The Ras superfamily of guanosine-triphosphate (GTP)-binding proteins regulates a diverse spectrum of intracellular processes involved in inflammation and fibrosis. Farnesythiosalicylic acid (FTS) is a unique and potent Ras inhibitor which decreased inflammation and fibrosis in experimentally induced liver cirrhosis and ameliorated inflammatory processes in systemic lupus erythematosus, neuritis and nephritis animal models. FTS effect on Ras expression and activity, muscle strength and fibrosis was evaluated in the dy2J/dy2J mouse model of merosin deficient congenital muscular dystrophy. The dy2J/dy2J mice had significantly increased RAS expression and activity compared with the wild type mice. FTS treatment significantly decreased RAS expression and activity. In addition, phosphorylation of ERK, a Ras downstream protein, was significantly decreased following FTS treatment in the dy2J/dy2J mice. Clinically, FTS treated mice showed significant improvement in hind limb muscle strength measured by electronic grip strength meter. Significant reduction of fibrosis was demonstrated in the treated group by quantitative Sirius Red staining and lower muscle collagen content. FTS effect was associated with significantly inhibition of both MMP-2 and MMP-9 activities. We conclude that active RAS inhibition by FTS was associated with attenuated fibrosis and improved muscle strength in the dy2J/dy2J mouse model of congenital muscular dystrophy. 相似文献
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