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The impoverished Antarctic decapod fauna is one of the most conspicuous biodiversity phenomena in polar science. Although physiological and ecological approaches have tried to explain the reason for the low decapod biodiversity pattern in the Southern Ocean, the complexity of this problem is still not completely understood. The scant records of crabs south of the Polar Front were always considered as exceptional, and have mostly been ignored by marine biologists world-wide, creating one of the most dogmatic paradigms in polar science. We herein review the record of both adults and larvae of reptants from the Southern Ocean. At present, several species of only lithodid crabs maintain considerable adult populations in circum-Antarctic waters, although they remain absent from the high-Antarctic shelves. 相似文献
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Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight 下载免费PDF全文
Sunlight causes lesions in DNA that if unrepaired and inaccurately replicated by DNA polymerases yield mutations that result in skin cancer in humans. Two enzymes involved in translesion synthesis (TLS) of UV-induced photolesions are DNA polymerase η (Polη) and polymerase ζ (Polζ), encoded by the RAD30A and REV3 genes, respectively. Previous studies have investigated the TLS roles of these polymerases in human and yeast cells irradiated with monochromatic, short wavelength UVC radiation (254 nm). However, less is known about cellular responses to solar radiation, which is of higher and mixed wavelengths (310–1100 nm) and produces a different spectrum of DNA lesions, including Dewar photoproducts and oxidative lesions. Here we report on the comparative cytotoxic and mutagenic effects of simulated sunlight (SSL) and UVC radiation on yeast wild-type, rad30Δ, rev3Δ and rev3Δ rad30Δ strains. The results with SSL support several previous interpretations on the roles of these two polymerases in TLS of photodimers and (6–4) photoproducts derived from studies with UVC. They further suggest that Polη participates in the non-mutagenic bypass of SSL-dependent cytosine-containing Dewar photoproducts and 8-oxoguanine, while Polζ is mainly responsible for the mutagenic bypass of all types of Dewar photoproducts. They also suggest that in the absence of Polζ, Polη contributes to UVC- and SSL-induced mutagenesis, possibly by the bypass of photodimers containing deaminated cytosine. 相似文献
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To determine whether replicational mutagenesis in the yeast genome is influenced by the positions of active origins, a reporter gene was placed in two orientations at multiple locations within a 39,000 bp region of chromosome III possessing two strong origins. The frequency of mutations resulting from misincorporation of adenine opposite 8-hydroxyguanine in one strand and 6-hydroxylaminopurine opposite cytosine in the other strand differed by 3- to 10-fold, depending on the gene orientation and its distance from the origins. The observed patterns indicate that active origins establish a strand bias for mutations that is maintained over thousands of base pairs and results from lower nucleotide selectivity and/or less efficient proofreading or mismatch repair during leading strand DNA replication. 相似文献
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The n-3 polyunsaturated fatty acids (PUFAs), EPA and DHA, as well as estrogen have been shown to decrease circulating levels of triglyceride (TG), but their underlying mode of action is unclear. The purpose of this study was to determine the effects of n-3 PUFA consumption and estrogen injection on TG metabolism. Rats (n = 48) were fed a modified AIN-93G diet with 0, 1, or 2 % EPA + DHA relative to the total energy intake during 12 weeks. At 8 weeks, rats were ovariectomized (OVX), and after a 1-week recovery, rats were injected with either 17β-estradiol-3-benzoate (E2) or corn oil for the last 3 weeks. The n-3 PUFA consumption and E2 injection independently decreased the hepatic expressions of sterol regulatory element-binding protein 1, acetyl-CoA carboxylase 1, fatty acid synthase (FAS), and diacylglycerol acyltransferase 2 (DGAT2) (P < 0.05). There were interactions between n-3 PUFA consumption and E2 injection on hepatic expression of FAS and DGAT2. In addition, n-3 PUFA consumption and E2 injection up-regulated the expression of AMP-activated protein kinase (AMPK), phosphorylated AMPK, peroxisomal proliferator-activated receptor α, and carnitine palmitoyltransferase 1 in liver and skeletal muscle. E2 injection increased the expression of estrogen receptor α and β in skeletal muscle and liver, but n-3 PUFA consumption increased the expression of both receptors only in skeletal muscle. The present study suggests that the hypotriglyceridemic effects of n-3 PUFA consumption and E2 injection could be due to the down-regulation of hepatic TG synthesis and up-regulation of TG oxidation in liver and skeletal muscle in OVX rats. 相似文献
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Velez J. A.; Watson W.; Sandknop E. M.; Arntz W.; Wolff M. 《Journal of plankton research》2003,25(3):279-290
Ontogeny of Normanichthys crockeri is described and illustratedbased on 66 specimens (1.920.5 mm; including recentlyhatched larvae through to the transformation stage) collectedin Bahia Independencia, Pisco, Peru. Larvae hatch at approximately1.8 mm, undergo notochord flexion at ca. 6.29.0 mm, andtransform to juveniles at ca. 20.0 mm. Larvae were identifiedby the series method, using a combination of meristic and developmentalcharacters that permitted definitive identification. Diagnosticfeatures of the larvae include early development of large, lightlypigmented pectoral fins; early dorsal midline pigment on thetrunk and tail which decreases gradually to none by the beginningof the flexion stage and does not reappear until late postflexionstage; and pigment ventrally, on the midlines of the abdominaland postanal regions, on the preanal until late postflexionstage, at the angular, on the caudal region, and usually atthe cleithrum. Larvae are moderately slender with preanal lengthroughly half of body length (ca. 4053% body length).They have I,5 pelvic-fin rays, 7+6 principal caudal-fin raysand 3637 myomeres (1113+2426, usually 13+24).The cleithra and bones of the jaws and opercular series areamong the first to begin ossifying. The anterior vertebrae beginto ossify at ca. 5.0 mm and addition is posteriorly. The pectoralfin is the first to begin ray formation, followed sequentiallyby the principal caudal-fin rays, second dorsal- and anal-finrays (forming concurrently), spiny dorsal-fin rays, and pelvic-finrays. 相似文献
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