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T. R. Nasibullin L. F. Yagafarova I. R. Yagafarov Ya. R. Timasheva V. V. Erdman I. A. Tuktarova O. E. Mustafina 《Russian Journal of Genetics》2016,52(8):860-867
Atherosclerosis represents an inflammatory response to the disturbance of the endothelial layer in the arterial bloodstream. In the present study, an analysis of associations of polymorphic markers for the genes controlling synthesis of proteins involved in atherosclerosis pathogenesis in coronary atherosclerosis (CA) patients (217 subjects) and in a control group (250 subjects) was conducted. The following genes were examined: rs991804 (CCL2 gene), rs1126579 (CXCR2 gene), rs4074 (CXCL1 gene), rs4073 (CXCL8 gene), rs333 (CCR5 gene), rs2471859 (CXCR4 gene), rs1801157 (CXCL12 gene), and rs2569190 (CD14 gene). Using the Monte Carlo and Markov chain (APSampler) method, allele/genotype combinations associated with both low and high CA risk were revealed. The most important findings included the following: CXCR4*T/T + CCL2*C + CCR5*I/I (Pperm = 1 × 10–6, OR = 0.44, 95% CI 0.3–0.63), CXCR2*C + CD14*C + CXCL12*G + CCL2*C + CCR5*D (Pperm = 4 × 10–6, OR = 5.78, 95% CI 2.34–14.28), CD14*C + CCL2*C/C + CCR5*D (Pperm = 6.3 × 10–6, OR = 5.81, 95% CI 2.17–15.56), CXCL8*A + CXCR2*C + CD14*T + CXCR4*C (Pperm = 0.01, OR = 3.21, 95% CI 1.63–6.31). 相似文献
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Yagafarova G. G. Gataullina E. M. Barakhnina V. B. Yagafarov I. R. Safarov A. Kh. 《Applied Biochemistry and Microbiology》2001,37(1):68-70
The strain Fusarium sp. no. 56 isolated from natural oil-containing soil samples taken near the city of Oktyabr'skii, Republic of Bashkortostan, displayed a pronounced capability of biotransforming oil and its light and heavy fractions. This micromycete is nonpathogenic and can grow at 5–10°C. The latter property is of practical significance for its uses in soil and water bioremediation under the cold climatic conditions of Bashkortostan and other regions. 相似文献
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Egorov A. R. Artemjev A. A. Kozyrev V. A. Sikaona D. N. Rubanik V. V. Rubanik Jr. V. V. Kritchenkov I. S. Yagafarov N. Z. Khubiev O. M. Tereshina T. A. Kultyshkina E. K. Medjbour B. Khrustalev V. N. Kritchenkov A. S. 《Applied Biochemistry and Microbiology》2022,58(2):132-135
Applied Biochemistry and Microbiology - The interaction of chitosan with 3-(chloromethyl)-[1,2,4]selendiazole[4,5-a]pyridin-4 bromide results in water-soluble, selenium-containing, cationic... 相似文献
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Yagafarova G. G. Safarov A. Kh. Ilina E. G. Yagafarov I. R. Barakhnina V. B. Sukharevich M. E. 《Applied Biochemistry and Microbiology》2002,38(5):441-444
The effect of oxidation products of shale kerogen (high-molecular-weight acids with 6–22 carbon atoms) on biodegradation of oil and oil products in soil and water was studied. High-molecular-weight acids (HMWA) not only affected the layer of oil and/or oil products and dispersed it into small particles, but also stimulated growth of Rhodococcus erythropolis VKM AS-1339D, degraders of oil and oil products. Addition of 0.001–0.003% HMWA to a medium to be purified from oil products increased the extent of bacterial biodegradation by a factor of 1.1–5.0. 相似文献
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