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Peerzada Tajamul Mumtaz Shakil Ahmad Bhat Syed Mudasir Ahmad Mashooq Ahmad Dar Raashid Ahmed Uneeb Urwat Aadil Ayaz Divya Shrivastava Riaz Ahmad Shah Nazir Ahmad Ganai 《Biological procedures online》2017,19(1):3
Immune responses combat various infectious agents by inducing inflammatory responses, antimicrobial pathways and adaptive immunity. The polygenic responses to these external stimuli are temporally and coordinately regulated. Specific lncRNAs are induced to modulate innate and adaptive immune responses which can function through various target interactions like RNA-DNA, RNA-RNA, and RNA-protein interaction and hence affect the immunogenic regulation at various stages of gene expression. LncRNA are found to be present in various immune cells like monocytes, macrophages, dendritic cells, neutrophils, T cells and B cells. They have been shown to be involved in many biological processes, including the regulation of the expression of genes, the dosage compensation and genomics imprinting, but the knowledge how lncRNAs are regulated and how they alter cell differentiation/function is still obscure. Further dysregulation of lncRNA has been seen in many diseases, but as yet very less research has been carried out to understand the role of lncRNAs in regulation during host-pathogens interactions. In this review, we summarize the functional developments and mechanism of action of lncRNAs, in immunity and defense of host against pathogens. 相似文献
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Urwat Uneeb Zargar Sajad Majeed Ahmad Syed Mudasir Ganai Nazir Ahmad 《Molecular biology reports》2021,48(3):2527-2531
Molecular Biology Reports - Mineral (Fe/Zn) stress significantly affects fundamental metabolic and physiological responses in plants that results in reduction of plant growth and development.... 相似文献
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