Comparative analysis of esterase and paraoxonase activities of different serum albumin species

Enzymatic activities of three types of serum albumin—rat, bovine and human—were analyzed comparatively using a mathematical model. Kinetic and equilibrium constants of carboxylesterase and paraoxonase activities of albumin in Sudlow’s sites I and II were determined. The effects of specific ligands, ibuprofen and warfarin, on enzyme kinetics in these sites were studied. Ibuprofen was found to have an inhibitory effect both on carboxylesterase and paraoxonase albumin activities, whereas warfarin specifically inhibited only carboxylesterase albumin activity.     

A Hypomagnetic Field Modulates the Susceptibility of Erythrocytes to tert-Butyl Hydroperoxide in Rats

Biophysics - Abstract—Red blood cells of rats were exposed to the earth’s magnetic field and an attenuated magnetic field in the presence of tert-butyl hydroperoxide to induce oxidative...     

Effect of Cys34 Oxidation State of Albumin on Its Interaction with Paraoxon according to Molecular Modeling Data

Russian Journal of Bioorganic Chemistry - The effect of the Cys34 oxidation state in human serum albumin on its binding and catalytic activity towards paraoxon was investigated using molecular...