全文获取类型
收费全文 | 983篇 |
免费 | 85篇 |
专业分类
1068篇 |
出版年
2022年 | 7篇 |
2021年 | 8篇 |
2017年 | 10篇 |
2016年 | 9篇 |
2015年 | 17篇 |
2014年 | 16篇 |
2013年 | 71篇 |
2012年 | 33篇 |
2011年 | 39篇 |
2010年 | 11篇 |
2009年 | 17篇 |
2008年 | 31篇 |
2007年 | 32篇 |
2006年 | 22篇 |
2005年 | 41篇 |
2004年 | 35篇 |
2003年 | 33篇 |
2002年 | 50篇 |
2001年 | 49篇 |
2000年 | 68篇 |
1999年 | 42篇 |
1998年 | 15篇 |
1997年 | 18篇 |
1996年 | 15篇 |
1995年 | 11篇 |
1994年 | 17篇 |
1993年 | 8篇 |
1992年 | 28篇 |
1991年 | 33篇 |
1990年 | 27篇 |
1989年 | 19篇 |
1988年 | 19篇 |
1987年 | 18篇 |
1986年 | 8篇 |
1985年 | 20篇 |
1984年 | 10篇 |
1983年 | 8篇 |
1982年 | 8篇 |
1980年 | 12篇 |
1979年 | 11篇 |
1978年 | 10篇 |
1975年 | 11篇 |
1974年 | 13篇 |
1973年 | 8篇 |
1972年 | 10篇 |
1971年 | 6篇 |
1970年 | 9篇 |
1968年 | 6篇 |
1967年 | 7篇 |
1966年 | 6篇 |
排序方式: 共有1068条查询结果,搜索用时 0 毫秒
1.
Y Aoyagi I Tasaki J Okumura T Muramatsu 《Comparative biochemistry and physiology. A, Comparative physiology》1988,89(3):433-436
1. Effect of low ambient temperature on protein turnover in the liver and whole body was investigated in chicks together with the contribution of protein synthesis to the total heat production. 2. Both protein synthesis and degradation in the whole body were increased, the latter to a larger extent, at low ambient temperature (LT, 22 degrees C) compared with adequate temperature (AT, 30 degrees C). Liver protein synthesis was not significantly altered by the temperature treatment. 3. The total heat production of LT group was as high as 160% of the AT group. 4. The increased heat production due to enhanced whole-body protein synthesis accounted for only 1.4% of the heat increment in thermogenesis at low ambient temperature, suggesting that protein synthesis would contribute little, if any, to cold-induced thermogenesis in chicks. 相似文献
2.
3.
Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF 总被引:21,自引:7,他引:14 下载免费PDF全文
K Hisatake T Nishimura Y Maeda K Hanada C Z Song M Muramatsu 《Nucleic acids research》1991,19(17):4631-4637
4.
5.
Striking homology of the ''variable'' N-terminal as well as the ''conserved core'' domains of the mouse and human TATA-factors (TFIID). 总被引:18,自引:9,他引:9 下载免费PDF全文
T Tamura K Sumita I Fujino A Aoyama M Horikoshi A Hoffmann R G Roeder M Muramatsu K Mikoshiba 《Nucleic acids research》1991,19(14):3861-3865
6.
I Muramatsu K Fujii Y Sakakibara M Fujiwara 《Canadian journal of physiology and pharmacology》1983,61(9):1071-1078
The effect of a novel antianginal agent, molsidomine (N-ethoxycarbonyl-3-morpholinosydnonimine) (SIN-10) and its metabolites, 3-morpholinosydnonimine (SIN-1) and N-nitroso-N-morpholinoaminoacetonitrile (SIN-1A) on isolated dog blood vessels were investigated. SIN-1 and SIN-1A elicited a concentration-dependent relaxation of prostaglandin F2 alpha, contracted strips, while SIN-10 was without effect even in a concentration of 10(-4) M. The mean effective concentration (EC50) values of SIN-1A were much lower than SIN-1 and other vasodilators including nitroglycerin. The time course of relaxation was more rapid and transient in response to SIN-1A than to SIN-1. Adrenergic and cholinergic blocking agents did not affect the relaxing responses to SIN-1 and SIN-1A. SIN-1A also attenuated the norepinephrine-, KCl-, Ca2+-, or electrical transmural stimulation-induced contractile response, but SIN-1A increased the [3H]norepinephrine release from the adrenergic nerve terminals in response to transmural stimulation. Methemoglobin, which reportedly binds nitric oxide, or methylene blue, an inhibitor of guanylate cyclase, attenuated the relaxing response to SIN-1A. These results indicate that the vasodilating action of molsidomine results from the direct action on the vascular smooth muscle and suggest that the action is caused by its metabolites, probably SIN-1A, which contains a nitric oxide-moiety in the molecule. The possible mechanism of vasorelaxing action of SIN-1A is discussed in comparison with that of nitroglycerin. 相似文献
7.
8.
9.
10.
Synthesis of 28-S RNA in the nucleolus 总被引:12,自引:0,他引:12