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1.
Karakaya Songul Göger Gamze Bona Gülnur Ekşi Yuca Hafize Aydın Bilge Tekman Enes Şahin Aydan Acar Pınar Nur Münevver Güvenalp Zühal 《Protoplasma》2022,259(6):1493-1506
Protoplasma - Colchicum speciosum Steven species is a perennial stemless plant. C. speciosum is a flowering herb native to mountainous regions of northern Turkey, the Caucasus, and northern Iran.... 相似文献
2.
Karakoc Y Buruk MS Aktan B Kirvar R Erdogan S Sahbaz MA Aksoy S Gulyasar T 《Biological trace element research》2011,144(1-3):1003-1007
In this study, we aimed to investigate whether chronic shift in light/dark cycle alters brain trace element concentrations. For this purpose, 20 male Wistar albino adult rats were weighed and randomly divided into three groups. The first group (n?=?6) was the control and had been subjected to 12/12-h light/dark cycle for 30?days. The second group (n?=?7) was subjected to 6/18-h light/dark cycle for 15?days, and the third group (n?=?7) was also subjected to 6/18-h light/dark cycle for 15?days and then returned to normal 12/12-h light/dark cycle for 15?days. When light/dark cycle protocols were completed, tissue specimens of the frontal lobe, temporal lobe, and brain stem were collected. Iron (Fe), zinc (Zn), and copper (Cu) concentrations of the frontal lobe, temporal lobe, and brain stem were determined by an atomic absorption spectrophotometer. When compared with controls, Fe levels of the temporal lobe significantly increased in 6/18-h light/dark cycle group (p?0.05), whereas it was statistically unchanged in rats which were exposed to 6/18-h light/dark cycle then returned to the normal 12/12-h light/dark cycle period. Our results show that chronic shift in light/dark cycle affects trace element concentrations of the brain, especially Fe level in the temporal lobe, and these changes are reversible. 相似文献
3.
Meliha Sengezer Inceli Engin Kaptan Serap Sancar Osman Murathanoglu Songul Suren Castillo 《Biologia》2010,65(1):157-163
The dorsal and ventral skin in amphibians plays an important role in osmoregulation. Prolactin hormone is involved in regulation
of amphibian skin functions, such as water and electrolyte balance. Therefore, amphibians may be useful as a model for determining
the sites of the prolactin receptor. In this study, prolactin receptor was detected in frog dorsal and ventral skin using
immunohistochemical staining method. Prolactin receptor immunoreactivity was localized in all epidermal layers except stratum
corneum of dorsal skin epidermis, stratum germinativum layer of ventral skin epidermis, myoepithelial cells, secretory epithelium
and secretory channel cells of granular glands in both skin regions. The mucous glands and secretory granules of granular
glands did not show immunoreactivity for the prolactin receptor. According to our immunohistochemical results, the more widespread
detection of prolactin receptor in dorsal skin epidermis indicates that prolactin is more effective in dorsal skin. Presence
of prolactin receptors in epidermis points out its possible osmoregulatory effect. Moreover, detection of receptor immunoreactivity
in various elements of poison glands in the dermis of both dorsal and ventral skin regions suggests that prolactin has a regulatory
effect in gland functions. 相似文献
4.
Songul Gurel Mehmet Cengiz Baloglu Ekrem Gurel Huseyin Avni Oktem Meral Yucel 《Plant Cell, Tissue and Organ Culture》2011,106(2):261-268
The effects of a two-stage pretreatment of seedlings on the subsequent shoot regeneration capacity were investigated. Pretreated
seedlings were obtained by germinating seeds on three different germination media and then further culturing on six different growth media. Lamina and petiole explants of two sugar beet (Beta
vulgaris L.) breeding lines were then excised from the pretreated seedlings and cultured on five different shoot regeneration media. In both breeding lines, petiole explants produced significantly more shoots than lamina explants with higher frequencies
of organogenic capacities; petiole explants of the lines M1195 and ELK345 produced a mean of 2.1 and 2.7 shoots per explant
while their lamina explants produced 1.5 and 2.2 shoots per explant, respectively. A genotypic variation was evident as the
line ELK345 was more productive for shoot development from both types of explants. In overall comparisons of different germination, growth and regeneration media, germination medium was most effective when supplemented with 0.5 mg/l 6-benzyladenine (BA) while both growth and regeneration
media were most productive when contained a combination of 0.25 mg/l BA and 0.10 mg/l indole-3-butyric acid (IBA). Of all
the treatments tested, the highest mean number of shoots per explant (8.3 shoots) and frequency of organogenic explants (75.6%)
were obtained on regeneration medium supplemented with 0.25 mg/l BA and 0.10 mg/l IBA when petiole explants of the line ELK345
were excised from the seedlings that had been germinated on medium containing 0.5 mg/l BA followed by further growth on medium
containing 0.25 mg/l BA and 0.10 mg/l IBA. 相似文献
5.
Ekrem Gurel Buhara Yucesan Esra Aglic Songul Gurel Sandeep K. Verma Munevver Sokmen Atalay Sokmen 《Plant Cell, Tissue and Organ Culture》2011,104(2):217-225
A high-frequency in vitro regeneration of Digitalis davisiana Heywood (Alanya foxglove) and cardiotonic glycoside production from both in vitro produced materials (regenerated plantlets
or germinated seedlings) and leaves of natural populations were obtained. Cardiac glycosides regulate heart rhythm and are
effective in cancer chemotherapy, in particular for prostate and breast cancer treatments. Testing six different types of
culture media revealed that Linsmaier and Skoog (LS) was the most effective for shoot production. Shoot regeneration efficiency
was higher when flamingo-bill or hypocotyl explants were cultured on LS medium containing 0.5 mg/l thidiazuron (TDZ) and 0.25 mg/l
indoleacetic acid (IAA). Rooting of all shoots that regenerated was readily achieved, even in the absence of plant growth
regulators (PGRs). Production of cardenolides (lanatoside C and digoxin) in the materials grown in vitro seemed to correlate
with several parameters, such as nutritional and hormonal compositions of the culture medium as well as the duration of culture
on the initial regeneration and/or final growth medium. Higher amounts of digoxin accumulation were obtained when shoots were
regenerated on LS or Gamborg’s B5 medium containing 0.5 mg/l TDZ and 0.25 mg/l IAA, producing 12.59 and 11.93 mg/kg dry weight
(dw) digoxin, respectively. For natural populations, seasonal variations seemed to affect the production of digoxin in the
leaves. The highest amount of digoxin (246.58 mg/kg dw) was in leaf samples collected in July, which coincides with the flowering
stage of the plant in the region of collection. 相似文献
6.
Nihal Cetin Bahtiyar Suleyman Ufuk Kuyrukluyildiz Hatice Sevim Nalkiran Altan Kiran Songul Gencoglu Ahmet Duzgun Ilker Zeki Kurtoglu Oguzhan Yarali Mehmet Ali Gul Halis Suleyman 《Experimental Animals》2016,65(1):77-85
No comparative study could be found for the analgesic activity of mucuses from the
Oncorhynchus mykiss (OM), Salvelinus fontinalis (SF),
Salmo coruhensis (SC), Acipenser gueldenstaedtii (AG),
and Acipenser baerii (AB) fish species in the literature. We aimed to
investigate the effects of mucuses obtained from the abovementioned fish species on
scalpel incision-induced pain in the rat paw and to examine the role of
oxidant/antioxidant parameters and COX-2 gene expression in the analgesic activities.
Animals were divided into groups: SIC (scalpel incision; SI), SIDS (SI+25 mg/kg diclofenac
sodium), SOM (SI+25 mg/kg OM mucus), SFM (SI+25 mg/kg SF mucus), SCM (SI+25 mg/kg SC
mucus), SAgM (SI+25 mg/kg AG mucus), SAbM (SI+25 mg/kg AB mucus), and HG (healthy). The
paw pain thresholds were measured with a Basile algesimeter before and after diclofenac
sodium (DS) or mucus administration, and then the rats were euthanized with thiopental
sodium. Oxidant/antioxidant and COX-2 gene expression parameters were measured in paw
tissues. OM, SC, AG, and AB fish mucuses could not decrease the SI-induced pain. However,
SF fish mucus prevented this pain by 69% after the first hour and by 58.3% after the third
hour. DS was shown to suppress pain more weakly than SF, preventing the pain by 62.1% and
50.0% after the first and third hours, respectively. SF mucus and DS significantly
inhibited increase of COX-2 gene expression, while other fish mucuses could not. None of
the fish mucuses except SF mucus in conjunction with DS could significantly inhibit the
increase in oxidant parameters and decrease in antioxidants. SF fish mucus should be
comparatively assessed in clinical practice for treatment of postoperative pain. 相似文献
7.
Osman Gulsen Songul Sever-Mutlu Nedim Mutlu Osman Karagüzel M. Murat Hocagil 《Biochemical Systematics and Ecology》2011,39(4-6):906-909
This study was carried out to determine genome sampling size of Cynodon accessions collected from Turkey for estimating genetic relatioships. One hundred and eighty-two Cynodon accessions collected in Turkey from an area south of the Taurus Mountains along the Mediterranean cost and ten known genotypes were genotyped using sequence related amplified polymorphism (SRAP) and the samples include diploids, triploids, tetraploids, pentaploids, and hexaploids. In this study, 182-markers were available from a previous work. We created 7 different data file, which include 5, 10, 20, 40, 60, 80, and 100 markers randomly selected from a 182-marker data file. First, similarity matrices was produced based on Dice’ and, alternatively, simple matching’ similarity coefficients for each data files. Then, a two-way mantel test was used to estimate Mantel correlation coefficients between each pair of similarity matrices. Mantel correlation coefficients between 5 and 10, 10 and 20, 20 and 40, 40 and 60, 60 and 80, and 80 and 100 marker-based simple matching’ similarity matrices were 0.718, 0.802, 0.826, 0.929, 0.977, and 0.975, respectively. Correlation estimates for the matrices based on Dice’s procedure for the same data sets were 0.863, 0.916, 0.930, 0.966, 0.965, and 0.984. The lower number of markers (10 or 20) was required with Dice’s procedure to achieve the higher correlation values (r > 0.9), and about random genome sampling size of 10 or 20 markers appeared to be sufficent in Cynodon accessions with a series of ploidy. This approach may apply to other plant species with ploidy series. 相似文献
8.
Osman Gulsen Songul Sever-Mutlu Nedim Mutlu Metin Tuna Osman Karaguzel Robert C. Shearman Terrance P. Riordan Tiffany M. Heng-Moss 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2009,118(7):1309-1319
Developing a better understanding of associations among ploidy level, geographic distribution, and genetic diversity of Cynodon accessions could be beneficial to bermudagrass breeding programs, and would enhance our understanding of the evolutionary
biology of this warm season grass species. This study was initiated to: (1) determine ploidy analysis of Cynodon accessions collected from Turkey, (2) investigate associations between ploidy level and diversity, (3) determine whether
geographic and ploidy distribution are related to nuclear genome variation, and (4) correlate among four nuclear molecular
marker systems for Cynodon accessions’ genetic analyses. One hundred and eighty-two Cynodon accessions collected in Turkey from an area south of the Taurus Mountains along the Mediterranean cost and ten known genotypes
were genotyped using sequence related amplified polymorphism (SRAP), peroxidase gene polymorphism (POGP), inter-simple sequence
repeat (ISSR), and random amplified polymorphic DNA (RAPD). The diploids, triploids, tetraploids, pentaploids, and hexaploids
revealed by flow cytometry had a linear present band frequency of 0.36, 0.47, 0.49, 0.52, and 0.54, respectively. Regression
analysis explained that quadratic relationship between ploidy level and band frequency was the most explanatory (r = 0.62, P < 0.001). The AMOVA results indicated that 91 and 94% of the total variation resided within ploidy level and provinces, respectively.
The UPGMA analysis suggested that commercial bermudagrass cultivars only one-third of the available genetic variation. SRAP,
POGP, ISSR, and RAPD markers differed in detecting relationships among the bermudagrass genotypes and rare alleles, suggesting
more efficiency of combinatory analysis of molecular marker systems. Elucidating Cynodon accessions’ genetic structure can aid to enhance breeding programs and broaden genetic base of commercial cultivars.
O. Gulsen and S. Sever-Mutlu contributed equally to this work. 相似文献
9.
Ata A Naz S Choudhary MI Atta-ur-Rahman Sener B Turkoz S 《Zeitschrift für Naturforschung. C, Journal of biosciences》2002,57(1-2):21-28
Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this species of genus Buxus. The structures of these new natural products were established on the basis of extensive spectroscopic studies. Compound 1 exhibited antibacterial activity against human pathogenic bacteria and weak phytotoxic activity against Lemna minor Linn. 相似文献
10.
Hafize Yuca Assoc. Songul Karakaya Assoc. Gülnur Ekşi Bilge Aydin Assoc. Gamze Goger Assoc. Mehmet Bona Enes Tekman Aydan Acar Şahin Prof. Oksana Sytar Prof. Nur Münevver Pinar Prof. Zuhal Guvenalp 《化学与生物多样性》2023,20(9):e202300416
Gagea genus, which is native to the Mediterranean and Black Sea regions, has attracted significant attention due to its biodiversity and potential health benefits. In this study, the biochemical composition and biological activities of methanol extracts from various parts of G. taurica were investigated, along with their anatomical and morphological characteristics. The best antimicrobial activity was found to be MeOH extracts of corm and leaf against several Candida strains with MIC=640 μg/mL. The highest level of phenolics together with significant results of antioxidant activities were observed in flowers extracts. The α-amylase inhibition assay results showed that the highest inhibition percentage was observed with acarbose (59 %), followed by leaf extract (43 %). Leaf exhibited the most effective inhibitory activity in AChE inhibition assay, whereas flower demonstrated the most significant inhibitory activity in BChE inhibition assay. Hesperidin was found as 1621.0001 ng/ml value in flower extract and 283.9339 ng/ml value leaf. 相似文献