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排序方式: 共有129条查询结果,搜索用时 15 毫秒
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T A Zapara O G Simonova A A Zharkikh A S Ratushniak 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》1999,85(1):128-138
Infringement of the Lymnaea stagnalis cytoskeleton condition affected preservation and repeated development of plastic responses. Stabilising of the microtubules led to a dependence of the development and preservation dynamics of the plastic responses. Stabilising of the microfilaments transformed short-term plastic responses into long-term ones. The findings suggest a key role of reorganisation of the cytoskeleton in neuronal plasticity. 相似文献
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A G Bezrukova A B Oreshkov V M Kolikov G M Simonova V A Bet'kenev 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1989,(9):11-14
Changes in the spectrum of the opacity of biodispersions containing L. acidophilus at the stage of growth have been studied. The pronounced positive correlation between the opacity of dispersion and the titer of cells, determined by the method of ultimate dilutions, have been shown. 相似文献
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R. N. Khramov I. M. Santalova L. I. Fakhranurova A. A. Manokhin N. B. Simonova D. I. Rzhevsky A. N. Murashev 《Biophysics》2010,55(3):447-452
The action of solar light transformed by special screens has been studied on CD-1 male mice. In the active control group,
mice were irradiated through screens absorbing the UV-component. In the experimental group, screens transforming the UV-component
into the orange-red light were used. In the active control, changes in the swimming activity, as compared to the same parameter
before irradiation, were manifested much less than in animals of the experimental group. A morphological analysis showed changes
in the structure of all cardiomyocyte organelles studied: the relative area of mitochondria in the experimental mice increased
by more than 20% compared to intact animals (p < 0.05). A significant increase in the area of the sarcoplasmic reticulum, by 23.4% (p < 0.05), and in the volume of the myofibrillar apparatus, by 19.4% (p < 0.05), was detected. The results of our experiment show that the irradiation with using an additional orangered component
improves the physical endurance 1.5 times and initiates morphogenetic processes in cardiac muscle cells. 相似文献
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V V Cherny M Paulitschke M V Simonova E Hessel V S Ermakov YuASokolov D Lerche V S Markin 《General physiology and biophysics》1989,8(1):23-37
The action of the antiviral drug rimantadine on the structure of bilayer lipid membranes (BLM) and RBC membranes was investigated. Structural changes in BLM were recorded by ionophore conductivity changes and by changes in the third harmonic of capacity current signal due to lateral compression of BLM in an electric field. It was shown that the adsorption of rimantadine on BLM results in an increase in ionophore mobility in bilayer membranes of dioleolyllecithin (DOL) and common lipids of bovine brain (CL) and in a decrease in those of azolectin (A). Relative changes in the third harmonic signal also depend on the membrane composition and have different signs. The results may be explained by the rimantadine action on the lipid bilayer structure: "rigidification" of A-membranes and "fluidization" of BLM from DOL and CL. Structural reorganization of RBC membranes as investigated by the ability of the cells to enter a micropipette (inner diameter greater than or equal to 3 microns) thereby undergoing deformation. It was shown that rimantadine influences RBC deformability due to drug induced inhomogenous mechanical membrane properties. Also, rimantadine accelerated the process of artificially induced aggregation of erythrocytes. The relation of the effects on artificial and biological membranes, and the structural changes in the lipid phase of membrane are discussed. 相似文献
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Alexander Varzari Vladimir Kharkov Alexey G. Nikitin Florina Raicu Kseniya Simonova Wolfgang Stephan Elisabeth H. Weiss Vadim Stepanov 《PloS one》2013,8(1)
Moldova has a rich historical and cultural heritage, which may be reflected in the current genetic makeup of its population. To date, no comprehensive studies exist about the population genetic structure of modern Moldavians. To bridge this gap with respect to paternal lineages, we analyzed 37 binary and 17 multiallelic (STRs) polymorphisms on the non-recombining portion of the Y chromosome in 125 Moldavian males. In addition, 53 Ukrainians from eastern Moldova and 54 Romanians from the neighboring eastern Romania were typed using the same set of markers. In Moldavians, 19 Y chromosome haplogroups were identified, the most common being I-M423 (20.8%), R-M17* (17.6%), R-M458 (12.8%), E-v13 (8.8%), R-M269* and R-M412* (both 7.2%). In Romanians, 14 haplogroups were found including I-M423 (40.7%), R-M17* (16.7%), R-M405 (7.4%), E-v13 and R-M412* (both 5.6%). In Ukrainians, 13 haplogroups were identified including R-M17 (34.0%), I-M423 (20.8%), R-M269* (9.4%), N-M178, R-M458 and R-M73 (each 5.7%). Our results show that a significant majority of the Moldavian paternal gene pool belongs to eastern/central European and Balkan/eastern Mediterranean Y lineages. Phylogenetic and AMOVA analyses based on Y-STR loci also revealed that Moldavians are close to both eastern/central European and Balkan-Carpathian populations. The data correlate well with historical accounts and geographical location of the region and thus allow to hypothesize that extant Moldavian paternal genetic lineages arose from extensive recent admixture between genetically autochthonous populations of the Balkan-Carpathian zone and neighboring Slavic groups. 相似文献
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Vorontsova Yu. E. Zavoloka E. L. Cherezov R. O. Simonova O. B. 《Russian Journal of Developmental Biology》2019,50(1):1-8
Russian Journal of Developmental Biology - The regulatory factors and biochemical properties of the actin cytoskeleton are widely studied in vitro and in cell cultures. However, it is... 相似文献
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