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Multicenter evaluation of the nitrate reductase assay for drug resistance detection of Mycobacterium tuberculosis 总被引:2,自引:0,他引:2
Martin A Montoro E Lemus D Simboli N Morcillo N Velasco M Chauca J Barrera L Ritacco V Portaels F Palomino JC 《Journal of microbiological methods》2005,63(2):145-150
The performance of the nitrate reductase assay was evaluated in a multicenter laboratory study to detect resistance of Mycobacterium tuberculosis to the first-line anti-tuberculosis drugs rifampicin, isoniazid, ethambutol and streptomycin using a set of coded isolates. Compared with the gold standard proportion method on L?wenstein-Jensen medium, the assay was highly accurate in detecting resistance to rifampicin, isoniazid and ethambutol with an accuracy of 98%, 96.6% and 97.9%, respectively. For streptomycin, discrepant results were obtained with an overall accuracy of 85.3%. The assay proved easy to be implemented in countries with limited laboratory facilities. 相似文献
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Simboli Alberto Taddeo Raffaella Raggi Andrea 《The International Journal of Life Cycle Assessment》2019,24(7):1285-1296
The International Journal of Life Cycle Assessment - This article analyses, in an industrial ecology (IE) perspective, urban contexts with specific features, such as a reduced space scale, a hybrid... 相似文献
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