全文获取类型
收费全文 | 13305篇 |
免费 | 1201篇 |
国内免费 | 3篇 |
出版年
2023年 | 97篇 |
2022年 | 240篇 |
2021年 | 467篇 |
2020年 | 261篇 |
2019年 | 326篇 |
2018年 | 394篇 |
2017年 | 333篇 |
2016年 | 561篇 |
2015年 | 792篇 |
2014年 | 843篇 |
2013年 | 1022篇 |
2012年 | 1220篇 |
2011年 | 1113篇 |
2010年 | 722篇 |
2009年 | 560篇 |
2008年 | 785篇 |
2007年 | 715篇 |
2006年 | 632篇 |
2005年 | 573篇 |
2004年 | 511篇 |
2003年 | 438篇 |
2002年 | 414篇 |
2001年 | 91篇 |
2000年 | 61篇 |
1999年 | 81篇 |
1998年 | 99篇 |
1997年 | 56篇 |
1996年 | 57篇 |
1995年 | 40篇 |
1994年 | 48篇 |
1993年 | 54篇 |
1992年 | 39篇 |
1991年 | 45篇 |
1990年 | 32篇 |
1989年 | 37篇 |
1988年 | 35篇 |
1987年 | 39篇 |
1986年 | 33篇 |
1985年 | 50篇 |
1984年 | 48篇 |
1983年 | 39篇 |
1982年 | 41篇 |
1981年 | 32篇 |
1980年 | 30篇 |
1979年 | 36篇 |
1978年 | 31篇 |
1977年 | 25篇 |
1976年 | 26篇 |
1974年 | 32篇 |
1972年 | 26篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
An earlier field study on the fifteen-spined stickleback (Spinachia
spinachia) showed that frequent malemale interactionsresult in high frequencies of sneaking and egg stealing. Moreover,sneaking behavior was performed not only by males adoptingalternative mating strategies, but also by males with theirown nests. The advantage of sneaking is easily understood,
but it is more difficult to explain the evolutionary benefitof stealing eggs from other males. I investigated whether malessuffering from sneaking adjust their paternal effort in relationto their degree of paternity. I also examined whether femalesprefer males that have more eggs in their nests, as this couldexplain egg stealing. There was no relationship between thedegree of paternity and fanning activity, hatching success,or nest defense. However, the older the eggs become, the morethe males increase their attack rate toward potential egg predators(goldsinny wrasse and shore crabs). Thus, males adjusted theirlevel of defense to the amount of energy and time already investedin the clutch. Females did not prefer males with more eggs intheir nests. On the contrary, females preferred males withreduced clutches over males with enlarged clutches. Therefore,female choice is unlikely to be a driving force behind eggstealing in this species. 相似文献
3.
4.
We used self‐reported data from United Methodist clergy to assess the prevalence of obesity and having ever been told certain chronic disease diagnoses. Of all actively serving United Methodist clergy in North Carolina (NC) 95% (n = 1726) completed self‐report height and weight items and diagnosis questions from the Behavioral Risk Factor Surveillance Survey (BRFSS). We calculated BMI categories and diagnosis prevalence rates for the clergy and compared them to the NC population using BRFSS data. The obesity rate among clergy aged 35–64 years was 39.7%, 10.3% (95% CI = 8.5%, 12.1%) higher than their NC counterparts. Clergy also reported significantly higher rates of having ever been given diagnoses of diabetes, arthritis, high blood pressure, angina, and asthma compared to their NC peers. Health interventions that address obesity and chronic disease among clergy are urgently needed. 相似文献
5.
Sara Ceballos Florentina Álvarez-Marqués 《Journal of experimental marine biology and ecology》2006,339(2):189-203
The reproductive activity and the physiological state of the calanoid copepods Calanus helgolandicus and Calanoides carinatus were investigated off the coast of NW Spain during autumn to evaluate the effect of short food resources on both populations. Phytoplankton biomass was low, and neither phytoplankton size distribution nor composition was suitable to support high reproductive rates. Accordingly, egg production rates (EPR) were much lower than maximum rates for both species, pointing to food limitation. The reproductive index (RI), which represents the proportion of females with mature gonads, was < 50% at each of the three zones into which the sampling area was divided (coast, shelf and ocean). Potential recruitment rates were very low except at some nearshore stations, where the highest concentrations of chlorophyll-a (Chl-a), diatoms, dinoflagellates and large cells were found. EPR of C. helgolandicus and C. carinatus were correlated with phytoplankton biomass and unaffected by temperature. Phytoplankton carbon ingestion explained ca. 50% of the variability in EPR for both species. At most of the stations, herbivory was insufficient to cover the carbon requirements for reproduction and respiration, so females probably fed on heterotrophic prey to meet their demands. However, given the low fecundity observed, this omnivorous diet did not seem to be optimum for reproduction, and a severe food limitation is thus suggested. Furthermore, the high C/N values measured point to a notable lipid storage, but given the low EPR found, lipid reserves were probably invested into female maintenance rather than into gonad maturation. C. helgolandicus and C. carinatus populations did not mirror phytoplankton biomass distribution, but they correlated well when considering only copepodites V (CV). The CV could be preparing for the overwintering, storing lipid reserves to ensure a successful diapause, and they could also be advected by the poleward current detected during the study. Females showed a diel feeding rhythm, with highest ingestion rates during night. From our results, it follows that C. helgolandicus and C. carinatus females did not perform diel vertical migrations. We suggest that this behaviour is likely due to the food-limiting conditions, which make it more advantageous to remain at the surface during daytime. 相似文献
6.
Diel changes in the near-surface (050 m) abundance, prosomelength, and carbon and nitrogen content of the copepod Metridialucens were measured in Deep Cove, Doubtful Sound, New Zealand(45°27'S, 167°9'E) between 3 and 6 September 1996. Metridialucens showed maximal abundance a night, suggesting a patternof normal diel vertical migration (DVM). The change in abundancesuggested that the descent of the population occurred 1h prior to dawn and the ascent 1 h after dusk. However,a proportion of the population remained near the surface duringthe day. Although there was no diel pattern in the prosome lengthof M.lucens collected near the surface, there was a marked dielcycle in the measured carbon and nitrogen contents, with maximalvalues being measured towards the end of the night prior tothe downward migration. We suggest that this diet cycle in themeasured elemental content was caused by DVM occurring morestrongly in those animals which had a better body condition,i.e. a higher elemental content per unit length. 相似文献
7.
Cathrine Laustrup M?ller Rasmus Kj?bsted Pablo J. Enriori Thomas Elbenhardt Jensen Cecilia Garcia-Rudaz Sara A. Litwak Kirsten Raun J?rgen Wojtaszewski Birgitte Schjellerup Wulff Michael A. Cowley 《PloS one》2016,11(7)
The melanocortin system includes five G-protein coupled receptors (family A) defined as MC1R-MC5R, which are stimulated by endogenous agonists derived from proopiomelanocortin (POMC). The melanocortin system has been intensely studied for its central actions in body weight and energy expenditure regulation, which are mainly mediated by MC4R. The pituitary gland is the source of various POMC-derived hormones released to the circulation, which raises the possibility that there may be actions of the melanocortins on peripheral energy homeostasis. In this study, we examined the molecular signaling pathway involved in α-MSH-stimulated glucose uptake in differentiated L6 myotubes and mouse muscle explants. In order to examine the involvement of AMPK, we investigate α-MSH stimulation in both wild type and AMPK deficient mice. We found that α-MSH significantly induces phosphorylation of TBC1 domain (TBC1D) family member 1 (S237 and T596), which is independent of upstream PKA and AMPK. We find no evidence to support that α-MSH-stimulated glucose uptake involves TBC1D4 phosphorylation (T642 and S704) or GLUT4 translocation. 相似文献
8.
Amanda McGrosky Carlo Meloro Ana Navarrete Sandra A. Heldstab Andrew C. Kitchener Karin Isler Marcus Clauss 《American journal of primatology》2019,81(8)
Although it is generally assumed that among mammals and within mammal groups, those species that rely on diets consisting of greater amounts of plant fiber have larger gastrointestinal tracts (GIT), statistical evidence for this simple claim is largely lacking. We compiled a dataset on the length of the small intestine, caecum, and colon in 42 strepsirrhine, platyrrhine, and catarrhine primate species, using specimens with known body mass (BM). We tested the scaling of intestine length with BM, and whether dietary proxies (percentage of leaves and a diet quality index) were significant covariates in these scaling relationships, using two sets of models: one that did not account for the phylogenetic structure of the data, and one that did. Intestine length mainly scaled geometrically at exponents that included 0.33 in the confidence interval; Strepsirrhini exhibited particularly long caeca, while those of Catarrhini were comparatively short. Diet proxies were only significant for the colon and the total large intestine (but not for the small intestine or the caecum), and only in conventional statistics (but not when accounting for phylogeny), indicating the pattern occurred across but not within clades. Compared to terrestrial Carnivora, primates have similar small intestine lengths, but longer large intestines. The data on intestine lengths presented here corroborate recent results on GIT complexity, suggesting that diet, as currently described, does not exhaustively explain GIT anatomy within primate clades. 相似文献
9.
Felix Roosen-Runge Marcus Hennig Tilo Seydel Fajun Zhang Maximilian W.A. Skoda Stefan Zorn Robert M.J. Jacobs Marco Maccarini Peter Fouquet Frank Schreiber 《Biochimica et Biophysica Acta - Proteins and Proteomics》2010,1804(1):68-75
We report on a combined cold neutron backscattering and spin-echo study of the short-range and long-range nanosecond diffusion of the model globular protein bovine serum albumin (BSA) in aqueous solution as a function of protein concentration and NaCl salt concentration. Complementary small angle X-ray scattering data are used to obtain information on the correlations of the proteins in solution. Particular emphasis is put on the effect of crowding, i.e. conditions under which the proteins cannot be considered as objects independent of each other. We thus address the question at which concentration this crowding starts to influence the static and in particular also the dynamical behaviour. We also briefly discuss qualitatively which charge effects, i.e. effects due to the interplay of charged molecules in an electrolyte solution, may be anticipated. Both the issue of crowding as well as that of charge effects are particularly relevant for proteins and their function under physiological conditions, where the protein volume fraction can be up to approximately 40% and salt ions are ubiquitous. The interpretation of the data is put in the context of existing studies on related systems and of existing theoretical models. 相似文献
10.
Nanoporous alumina membranes were silanized with aminopropylsilane and iminodiacetic acid (IDA) groups were generated in situ by reaction with iodoacetate. The membranes were mounted in standard filter holders, connected to a HPLC system and saturated with selected metal ions. Cu(II) allowed the capture of chicken muscle lactate dehydrogenase with such stability, repeatability and reproducibility that Michaelis–Menten kinetics could be studied. The IDA surface was stable for months and could be depleted and regenerated with metal ions multiple times without appreciable loss of capacity. The binding of lactate dehydrogenase influenced the backpressure to the extent that could be expected for a monolayer according to Poiseuilles law. 相似文献