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Salome Kiparoidze Nino Karumidze Ekaterine Bakuradze Irina Modebadze Levan Rusishvili Dimitri Kordzaia Diana Dzidziguri 《Molecular & cellular biomechanics : MCB》2021,18(3):131-138
According to the literature, different mechanisms and kinetics proceeding of regenerative growth has been established using the basic models of liver regeneration (after resection or chemically induced). Hence, in order to determine general regularities of the adaptive-compensatory processes in various pathological conditions, the processes taking place in the cholestatic liver of adult white rats during the first four days after common bile duct ligation have been studied. It has been shown that in cholestatic liver, compensatory-adaptive processes take place with different kinetics compared to those after resection. In particular, in response to the increased functional load caused by destructive processes during cholestasis, the liver, at an early stage, responds by simple division of high ploidy (binuclear tetraploid) cells and further provides their quantitative increase. The difference between the processes taking place in cholestatic and resected liver is more expressed on the third and fourth day after common bile duct ligation. In particular, 4c cells are still highest in cholestatic liver, while all ploidy cells are present in equal numbers in the regenerated liver after resection. This fact of compensatory growth characteristic for reparative regeneration was not detected in cholestatic liver at the mentioned date. 相似文献
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Giorgobiani N Dzidziguri D Rukhadze M Rusishvili L Tumanishvili G 《Cell biology international》2005,29(12):1047-1049
A hydrophilic protein component (12-17 kDa) of the thermostable protein complex (TSPC) of different organs (heart, liver, kidney, brain) of adult white rats has been identified using hydrophobic interaction chromatography (HIC). Chromatograms and spectra of the myocardial hydrophilic component of different animals (snail, pigeon, rat, pig) detected within the UV region (190-360 nm) have shown that in different organs of the same animal species as well as in the same organ (e.g. heart) of different species, TSPC contains identical hydrophilic components, i.e. there is clearly a phylogenetically conserved group of thermostable proteins that regulates proliferation processes. 相似文献
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Bouby Laurent Wales Nathan Jalabadze Mindia Rusishvili Nana Bonhomme Vincent Ramos-Madrigal Jazmín Evin Allowen Ivorra Sarah Lacombe Thierry Pagnoux Clémence Boaretto Elisabetta Gilbert M. Thomas P. Bacilieri Roberto Lordkipanidze David Maghradze David 《Vegetation History and Archaeobotany》2021,30(1):63-76
Vegetation History and Archaeobotany - The Near East and the Caucasus are commonly regarded as the original domestication centres of Vitis vinifera (grapevine), and the region continues to be home... 相似文献
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