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Rafael M. Ronsoni Tiago L. Silvestrini Vidal Essebag Renato D. Lopes Marco Aurélio Lumertz Saffi Tiago Luiz Luz Leiria 《Indian pacing and electrophysiology journal》2021,21(2):95-100
IntroductionElectrical pulmonary vein isolation (PVI) is used for the invasive treatment of atrial fibrillation (AF). However, despite the procedure’s technical evolution, the rate of AF recurrence due to electrical reconnection of the PVs is high. The aims of this study was to assess the influence of left common pulmonary venous ostium (LCO) on clinical outcomes following PVI.MethodsRetrospective cohort of 254 patients who underwent the first procedure of PVI from the years 2013–2018 was assessed. Patients with persistent AF of long duration and extra-pulmonary focus associated with triggers for arrhythmia were excluded. Patients were stratified into two groups according to the presence of a LCO and received follow up for atrial tachyarrhythmia-free survival. The mean follow-up period was 28 ± 1.73 months.ResultsThe majority were men (68.5%), with a mean age of 54 ± 12 years. With respect to the atrial anatomy, LCO occurred in 23.6% of cases after pulmonary venous angiotomography. The arrhythmia-free survival rate was 79.5% in the follow-up period. The Cox regression model was utilized and the adjusted hazard ratio for LCO was 0.36 (95% CI 0.15–0.87; p = 0.02) in terms of age, body mass index, left atrium diameter, bi-directional blocking of the cavotricuspid isthmus, persistent AF, left ventricular ejection fraction adjusted model.ConclusionAnatomic abnormality with the presence of the LCO is present in a quarter of patients undergoing AF ablation, which is associated with a lower rate of arrhythmia recurrence in our population. 相似文献
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Ronsoni Marcelo Fernando Remor Aline Pertile Lopes Mark William Hohl Alexandre Troncoso Iris H. Z. Leal Rodrigo Bainy Boos Gustavo Luchi Kondageski Charles Nunes Jean Costa Linhares Marcelo Neves Lin Kátia Latini Alexandra Susana Walz Roger 《Neurochemical research》2016,41(4):880-891
Neurochemical Research - Mitochondrial respiratory chain complexes enzymatic (MRCCE) activities were successfully evaluated in frozen brain samples. Epilepsy surgery offers an ethical opportunity... 相似文献
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Bruno da Silveira Colombo Marcelo Fernando Ronsoni Pedro Eduardo Soares e Silva Leonardo Fayad Letícia Muraro Wildner Maria Luiza Bazzo 《Biomarkers》2017,22(2):127-132
Context: IGF-I serum levels are suppressed in cirrhosis, but its prognostic significance is unknown.
Objectives: To investigate the prognostic value of IGF-I in patients admitted for acute decompensation of cirrhosis.
Materials and methods: Cohort study that included 103 patients. IGF-I was measured by enzyme-linked immunosorbent assay (ELISA).
Results: Ninety-day mortality was 26.2% and it was independently associated with MELD, age and IGF-I. The Kaplan–Meier survival probability at 90 days was 94.3% in patients with IGF-I?≥13?ng/mL and 63.2% for patients with IGF-I?<13?ng/mL (p?=?.001).
Discussion and conclusion: IGF-I levels are independently associated with mortality in acute decompensation of cirrhosis. 相似文献
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