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Patrone Vania Al-Surrayai Tahani Romaniello Francesco Fontana Alessandra Milani Giovanni Sagheddu Valeria Puglisi Edoardo Callegari Maria Luisa Al-Mansour Hamad Kishk Mohamed Waheed Morelli Lorenzo 《Probiotics and antimicrobial proteins》2021,13(3):809-823
Probiotics and Antimicrobial Proteins - Probiotics represent a possible strategy for controlling intestinal infections in livestock. Members of the Weissella genus are increasingly being studied... 相似文献
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R. N. Hook M. Romaniello M. Ullgrén P. J?rvel?inen S. Maisala et al. 《Plant molecular biology》1991,17(3):iii-iii
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Marta Romani Francesca Mancini Alessia Micalizzi Andrea Poretti Elide Miccinilli Patrizia Accorsi Emanuela Avola Enrico Bertini Renato Borgatti Romina Romaniello Serdar Ceylaner Giangennaro Coppola Stefano D’Arrigo Lucio Giordano Andreas R. Janecke Mario Lituania Kathrin Ludwig Loreto Martorell Tommaso Mazza Sylvie Odent Lorenzo Pinelli Pilar Poo Margherita Santucci Sabrina Signorini Alessandro Simonati Ronen Spiegel Franco Stanzial Maja Steinlin Brahim Tabarki Nicole I. Wolf Federica Zibordi Eugen Boltshauser Enza Maria Valente 《Human genetics》2015,134(1):123-126
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Feifei Zhang Shuhai Xiao Stephen J. Romaniello Dalton Hardisty Chao Li Victor Melezhik Boris Pokrovsky Meng Cheng Wei Shi Timothy M. Lenton Ariel D. Anbar 《Geobiology》2019,17(6):594-610
The role of O2 in the evolution of early animals, as represented by some members of the Ediacara biota, has been heavily debated because current geochemical evidence paints a conflicting picture regarding global marine O2 levels during key intervals of the rise and fall of the Ediacara biota. Fossil evidence indicates that the diversification the Ediacara biota occurred during or shortly after the Ediacaran Shuram negative C‐isotope Excursion (SE), which is often interpreted to reflect ocean oxygenation. However, there is conflicting evidence regarding ocean oxygen levels during the SE and the middle Ediacaran Period. To help resolve this debate, we examined U isotope variations (δ238U) in three carbonate sections from South China, Siberia, and USA that record the SE. The δ238U data from all three sections are in excellent agreement and reveal the largest positive shift in δ238U ever reported in the geologic record (from ~ ?0.74‰ to ~ ?0.26‰). Quantitative modeling of these data suggests that the global ocean switched from a largely anoxic state (26%–100% of the seafloor overlain by anoxic waters) to near‐modern levels of ocean oxygenation during the SE. This episode of ocean oxygenation is broadly coincident with the rise of the Ediacara biota. Following this initial radiation, the Ediacara biota persisted until the terminal Ediacaran period, when recently published U isotope data indicate a return to more widespread ocean anoxia. Taken together, it appears that global marine redox changes drove the rise and fall of the Ediacara biota. 相似文献
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Fernanda Ramos Gomes Vincenzo Romaniello Araceli Sánchez Claudia Weber Pratibha Narayanan Maryna Psol Luis A. Pardo 《The Journal of biological chemistry》2015,290(51):30351-30365
KV10.1 is a voltage-gated potassium channel expressed selectively in the mammalian brain but also aberrantly in cancer cells. In this study we identified short splice variants of KV10.1 resulting from exon-skipping events (E65 and E70) in human brain and cancer cell lines. The presence of the variants was confirmed by Northern blot and RNase protection assays. Both variants completely lacked the transmembrane domains of the channel and produced cytoplasmic proteins without channel function. In a reconstituted system, both variants co-precipitated with the full-length channel and induced a robust down-regulation of KV10.1 current when co-expressed with the full-length form, but their effect was mechanistically different. E65 required a tetramerization domain and induced a reduction in the overall expression of full-length KV10.1, whereas E70 mainly affected its glycosylation pattern. E65 triggered the activation of cyclin-dependent kinases in Xenopus laevis oocytes, suggesting a role in cell cycle control. Our observations highlight the relevance of noncanonical functions for the oncogenicity of KV10.1, which need to be considered when ion channels are targeted for cancer therapy. 相似文献
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Patrizia Romano Angela Capece Vincenza Serafino Rossana Romaniello Cinzia Poeta 《World journal of microbiology & biotechnology》2008,24(9):1797-1802
The principal agent in winemaking is the yeast Saccharomyces cerevisiae, which is characterized by a significant strain biodiversity. Here we report the characterization of 80 wild S. cerevisiae strains, isolated from grapes of different varieties in southern Italy, for genetic and technological variability. By PCR
amplification with M13 primer a significant polymorphism was recorded and 12 different biotypes were identified among the
strains. The specific strain-pattern could be used to follow the dynamics of different biotypes during the fermentation process.
The analysis of experimental wines obtained by inoculated fermentations with the 80 strains showed significant differences
among the wines. The level of each compound was a function of the strain performing the fermentative process. The main variables
for the strain differentiation were the production of acetaldehyde and acetic acid, which ranged from 53 to 282 mg/l and from
0.20 to 1.88 g/l, respectively. Selected strains were tested in fermentation with two different grape musts, yielding experimental
wines differing in the levels of secondary compounds and polyphenol content, in function of the interaction “grape must composition/yeast
strain”. This finding has an applicative value for the potentiality of utilizing the resource of strain variability as a tool
to individuate suitable starter cultures, which are able to complement and optimize grape quality. 相似文献
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