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Itaru Hirai Tadahiro Sasaki Ai Kimoto Yoshimasa Yamamoto Takeshi Azuma Varocha Mahachai Piyathida Hansomburana Comsun Lertkupinit Somchai Luangjaru Phadet Noophan Rattikorn Chanatrirattanapan Vanich Piyanirandr Theeranan Sappajit Karun Suthivarakom Leelaowadee Sangsuk Piyada Wangroongsarb 《Microbes and infection / Institut Pasteur》2010,12(3):227-230
In Thailand, gastric cancer incidence is considerably low despite the high prevalence of Helicobacter pylori infection. We investigated the prevalence of H. pylori infection and the genotypes of cagA by using 179 stool specimens obtained from asymptomatic Thai individuals. In this study, the prevalence of H. pylori infection was 43.6%, and the detection rate of cagA-positive strains was 43.5%. In addition, the proportion of the highly virulent East-Asian type of cagA was 7.2%. These results indicate that the low prevalence of cagA-positive H. pylori strain as well as the low prevalence of East-Asian genotype cagA-positive strains may contribute to the low gastric cancer incidence. 相似文献
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