全文获取类型
收费全文 | 568篇 |
免费 | 22篇 |
国内免费 | 1篇 |
出版年
2022年 | 8篇 |
2021年 | 14篇 |
2020年 | 7篇 |
2019年 | 7篇 |
2018年 | 21篇 |
2017年 | 9篇 |
2016年 | 19篇 |
2015年 | 16篇 |
2014年 | 22篇 |
2013年 | 19篇 |
2012年 | 27篇 |
2011年 | 30篇 |
2010年 | 11篇 |
2009年 | 14篇 |
2008年 | 19篇 |
2007年 | 21篇 |
2006年 | 12篇 |
2005年 | 16篇 |
2004年 | 16篇 |
2003年 | 9篇 |
2002年 | 16篇 |
2001年 | 14篇 |
2000年 | 11篇 |
1999年 | 13篇 |
1996年 | 6篇 |
1994年 | 4篇 |
1992年 | 8篇 |
1991年 | 14篇 |
1990年 | 10篇 |
1989年 | 14篇 |
1988年 | 14篇 |
1987年 | 14篇 |
1986年 | 6篇 |
1985年 | 10篇 |
1984年 | 12篇 |
1983年 | 10篇 |
1980年 | 3篇 |
1979年 | 10篇 |
1978年 | 8篇 |
1977年 | 8篇 |
1976年 | 4篇 |
1975年 | 6篇 |
1974年 | 5篇 |
1973年 | 5篇 |
1972年 | 8篇 |
1971年 | 7篇 |
1970年 | 4篇 |
1969年 | 4篇 |
1968年 | 4篇 |
1967年 | 6篇 |
排序方式: 共有591条查询结果,搜索用时 967 毫秒
1.
2.
Using fluorimetric and polarographic determination of cell respiration, metabolic reactions of the carotid body of rats to adequate stimulation have been revealed. Functional relationships of the dose--effect type, which were found for these reactions, may be approximated by equations which are similar to those describing the unconditioned reflexes from the carotid chemoreceptors. However, reactions of the metabolics systems of the carotid body account for the perception of not all chemical stimuli, but only of acids and some alkaloids. These data reveal the heteregeneity of the carotid chemosensory system not only in the amphibians (which was known earlier), but in mammals as well. 相似文献
3.
T N Kuchma N D Konstantinova I S Samo?lenko 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1990,(9):20-23
The comparative study of the action of microwave radiation and hydrogen peroxide, as well as their combined action, on the viability and ultrastructure of P. aeruginosa cells has been made. The combined use of microwave radiation and hydrogen peroxide has been shown to decrease the viability of P. aeruginosa 1.5-2 times in comparison with the isolated action of each factor. The electron microscopic study of the ultrastructure of cells have shown the deterioration of the surface structures, nuclear and ribosomal apparatus of the cells under the isolated action of each of the above-mentioned factors or under their combined action. The morphological picture of these changes has proved to be different. The maximum changes in the ultrastructure of P. aeruginosa cells have been registered after the combined action of these bactericidal factors. 相似文献
4.
The advantage of using terrestrial isopods in toxicity studies is that a battery of parameters can be tested at different levels of biological complexity. Feeding parameters for example link organism level response to potential ecological consequences but a problem with using feeding parameters in toxicity tests with terrestrial isopods is their high variability. The aim of our study was to set benchmark values for feeding parameters for isopod Porcellio
scaber (Isopoda, Crustacea) in laboratory-controlled experiments. In the work presented here, the daily feeding rate of the central 50% of the control population of Porcellio
scaber and a correlation between feeding rate and isopod weight were set. Values outside these ranges need additional evaluation to increase the relevance of test outcomes. We suggest using benchmark values for feeding parameters as well as the coefficient of variation (a) to identify animals with altered feeding parameters with respect to controls, and (b) to assess the data quality in each experiment. 相似文献
5.
Cucumber ( Cucumis sativus L. cv. Poinsett 76) seeds were chilled at 2.5°C in a study of the chilling sensitivity and recovery of radicle tissue. The effect of chilling on radicle growth and the production of carbon dioxide and ethylene was measured. Chilling sensitivity of radicles increased as they grew from 1 to 7 mm in length. The length, not the age of the radicles, determined the level of chilling sensitivity. Apical tissue was most sensitive to chilling and slowest to recover from chilling, followed by subapical and basal tissue. Our data demonstrate that the chilling sensitivity of young seedling radicles differs along their length and that the rapid chilling-induced inhibition of elongation is probably due to an inability of meristematic cells to remain viable and active when chilled. 相似文献
6.
V N Obolenski? L S Aronov G V Rodoman A V Novikov L N Samo?lova V R Ga?tukaev 《Antibiotiki i khimioterapii͡a》2004,49(10):13-19
The clinical and economic efficacies of antibiotic prophylaxis in the surgical unit of the Hospital were confirmed by the results of the analysis of 1313 case records of the patients operated during a year for acute appendicitis and acute cholecystitis. At the same time it was shown advisable to use antibiotic therapy in the patients with various pathological processes. The dynamics of the microbial dissemination in the surgical unit and some other units of the Hospital, as well as the dynamics of antibiotic resistance of the microflora, its interrelation with the volume of the antibacterials used and their rotation are described. 相似文献
7.
Interactions between intrinsic regulation and neural modulation of acetylcholinesterase in fast and slow skeletal muscles 总被引:2,自引:0,他引:2
Janez Sketelj Neva Črne-Finderle Samo Ribarič Miro Brzin 《Cellular and molecular neurobiology》1991,11(1):35-54
1. Initiation of subsynaptic sarcolemmal specialization and expression of different molecular forms of AChE were studied in fast extensor digitorum longus (EDL) and slow soleus (SOL) muscle of the rat under different experimental conditions in order to understand better the interplay of neural influences with intrinsic regulatory mechanisms of muscle cells. 2. Former junctional sarcolemma still accumulated AChE and continued to differentiate morphologically for at least 3 weeks after early postnatal denervation of EDL and SOL muscles. In noninnervated regenerating muscles, postsynaptic-like sarcolemmal specializations with AChE appeared (a) in the former junctional region, possibly induced by a substance in the former junctional basal lamina, and (b) in circumscribed areas along the whole length of myotubes. Therefore, the muscle cells seem to be able to produce a postsynaptic organization guiding substance, located in the basal lamina. The nerve may enhance the production or accumulation of this substance at the site of the future motor end plate. 3. Significant differences in the patterns of AChE molecular forms in EDL and SOL muscles arise between day 4 and day 10 after birth. The developmental process of downregulation of the asymmetric AChE forms, eliminating them extrajunctionally in the EDL, is less efficient in the SOL. The presence of these AChE forms in the extrajunctional regions of the SOL correlates with the ability to accumulate AChE in myotendinous junctions. The typical distribution of the asymmetric AChE forms in the EDL and SOL is maintained for at least 3 weeks after muscle denervation. 4. Different patterns of AChE molecular forms were observed in noninnervated EDL and SOL muscles regenerating in situ. In innervated regenerates, patterns of AChE molecular forms typical for mature muscles were instituted during the first week after reinnervation. 5. These results are consistent with the hypothesis that intrinsic differences between slow and fast muscle fibers, concerning the response of their AChE regulating mechanism to neural influences, may contribute to different AChE expression in fast and slow muscles, in addition to the influence of different stimulation patterns. 相似文献
8.
Kirit D. Chapatwala Mohamed S. Nawaz Juddie D. Richardson James H. Wolfram 《Journal of industrial microbiology & biotechnology》1990,5(2-3):65-69
Summary Bacteria utilizing high concentrations of acetonitrile as the sole carbon source were isolated and identified asChromobacterium sp. andPseudomonas aeruginosa. Maximum growth was attained after 96 h of incubation andP. aeruginosa grew slightly faster thanChromobacterium sp. The strains were able to grow and oxidize acetonitrile at concentrations as high as 600 mM. However, higher concentrations inhibited growth and oxygen uptake. Degradation studies with (14C)acetonitrile indicated 57% of acetonitrile was degraded byPseudomonas aeruginosa as compared to 43% byChromobacterium. The isolates utilized different nitrile compounds as carbon substrates. 相似文献
9.
Rodriguez Maria E. Hozbor Daniela F. Samo Analia L. Ertola Rodolfo Yantorno Osvaldo M. 《Journal of industrial microbiology & biotechnology》1994,13(5):273-278
Summary The kinetics ofBordetella pertussis growth was studied in a glutamate-limited continuous culture. Growth kinetics corresponded to Monod's model. The saturation constant and maximum specific growth rate were estimated as well as the energetic parameters, theoretical yield of cells and maintenance coefficient. Release of pertussis toxin (PT) and lipopolysaccharide (LPS) were growth-associated. In addition, they showed a linear relationship between them. Growth rate affected neither outer membrane proteins nor the cell-bound LPS pattern.Nomenclature X
cell concentration (g L–1)
-
specific growth rate (h–1)
- m
maximum specific growth rate (h–1)
- D
dilution rate (h–1)
- S
concentration of growth rate-limiting nutrient (glutamate) (mmol L–1 or g L–1)
- Ks
substrate saturation constant (mol L–1)
- ms
maintenance coefficient (g g–1 h–1)
- Yx/s
theoretical yield of cells from glutamate (g g–1)
- Yx/s
yield of cells from glutamate (g g–1)
- YPT/s
yield of soluble PT from glutamate (mg g–1)
- YKDO/s
yield of cell-free KDO from glutamate (g g–1)
- YPT/x
specific yield of soluble PT (mg g–1)
- YKDO/x
specific yield of cell-free KDO (g g–1)
- qPT
specific soluble PT production rate (mg g–1 h–1)
- qKDO
specific cell-free KDO production rate (g g–1 h–1) 相似文献
10.