Protein–protein interactions of huntingtin in the hippocampus

Molecular Biology - Huntingtin (HTT) occurs in the neuronal cytoplasm and can interact with structural elements of synapses. Huntington’s disease (HD) results from pathological expansion of a...     

Cross-Talk of the Glutamate and Leptin Receptor Pathways

Molecular Biology - The hormone leptin is produced in adipocytes of white adipose tissue and crosses the blood–brain barrier. Leptin receptors are present in the brain regions that are...     

Identification of Tumor Dissemination Facilitating Proteins in Exosomes Associated with Blood Cells of Breast Cancer Patients

Russian Journal of Bioorganic Chemistry - Exosomes are important intercellular communication vehicles, secreted into body fluids by multiple cell types, including tumor cells. Exosomes stimulate...