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Radchatawedchakoon W. Niyomtham N. Thongbamrer C. Posa C. Sakee U. Roobsoong W. Sattabongkot J. Opanasopit P. Yingyongnarongkul B. 《Russian Journal of Bioorganic Chemistry》2020,46(3):417-428
Russian Journal of Bioorganic Chemistry - Cationic lipids with amide or carbamate linker and divalent cationic headgroups were synthesized for a transfection study. Sixteen cationic lipids with... 相似文献
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Navjot S. Sodhi Mary Rose C. Posa Tien Ming Lee David Bickford Lian Pin Koh Barry W. Brook 《Biodiversity and Conservation》2010,19(2):317-328
Southeast Asia is a region of conservation concern due to heavy losses of its native habitats. In this overview, we highlight
the conservation importance of Southeast Asia by comparing its degree of species endemism and endangerment, and its rate of
deforestation with other tropical regions (i.e., Meso-America, South America, and Sub-Saharan Africa). Southeast Asia contains
the highest mean proportion of country-endemic bird (9%) and mammal species (11%). This region also has the highest proportion
of threatened vascular plant, reptile, bird, and mammal species. Furthermore, not only is Southeast Asia’s annual deforestation
rate the highest in the tropics, but it has also increased between the periods 1990–2000 and 2000–2005. This could result
in projected losses of 13–85% of biodiversity in the region by 2100. Secondary habitat restoration, at least in certain countries,
would allow for some amelioration of biodiversity loss and thus potentially lower the currently predicted extinction rates.
Nonetheless, urgent conservation actions are needed. Conservation initiatives should include public education, sustaining
livelihoods, and ways to enhance the sustainability of agriculture and increase the capacity of conservation institutions.
Furthermore, these actions should be country-specific and not ignore areas heavily populated by humans, as they can also harbour
high numbers of threatened species. We urge that cooperative conservation initiatives be undertaken and support (e.g., capacity-building)
be given by more developed countries in the region and beyond. 相似文献
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Ferenc Torma Erika Koltai Enik? Nagy Mohammad Mosaferi Ziaaldini Aniko Posa Lauren G. Koch Steven L. Britton Istvan Boldogh Zsolt Radak 《PloS one》2014,9(12)
The oxidative stress effect of exercise training on testis function is under debate. In the present study we used a unique rat model system developed by artificial selection for low and high intrinsic running capacity (LCR and HCR, respectively) to evaluate the effects of exercise training on apoptosis and spermatogenesis in testis. Twenty-four 13-month-old male rats were assigned to four groups: control LCR (LCR-C), trained LCR (LCR-T), control HCR (HCR-C), and trained HCR (HCR-T). Ten key proteins connecting aerobic exercise capacity and general testes function were assessed, including those that are vital for mitochondrial biogenesis. The VO2 max of LCR-C group was about 30% lower than that of HCR-C rats, and the SIRT1 levels were also significantly lower than HCR-C. Twelve weeks of training significantly increased maximal oxygen consumption in LCR by nearly 40% whereas HCR remained unchanged. LCR-T had significantly higher levels of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1α), decreased levels of reactive oxygen species and increased acetylated p53 compared to LCR-C, while training produced no significant changes for these measures in HCR rats. BAX and Blc-2 were not different among all four groups. The levels of outer dense fibers -1 (Odf-1), a marker of spermatogenesis, increased in LCR-T rats, but decreased in HCR-TR rats. Moreover, exercise training increased the levels of lactate dehydrogenase C (LDHC) only in LCR rats. These data suggest that rats with low inborn exercise capacity can increase whole body oxygen consumption and running exercise capacity with endurance training and, in turn, increase spermatogenesis function via reduction in ROS and heightened activity of p53 in testes. 相似文献
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Scott V. C. Groom Hien T. Ngo Sandra M. Rehan Posa Skelton Mark I. Stevens Michael P. Schwarz 《Biological invasions》2014,16(11):2293-2302
The islands of the south west Pacific (SWP) are highly biodiverse, yet records of their bee fauna suggest a region depauperate of a key pollinator suite. Studies of the bees of Fiji based on molecular data have revealed a recent origin with the majority of species having arrived since the last glacial maximum or introduced since human colonization. Here we use DNA barcodes to provide the first detailed account of Apidae bees from Vanuatu, Fiji, and Samoa. We show that most if not all species in these archipelagos have been recently introduced from Australia and south east Asia, with a further species introduced from the New World. Some of these species have become regionally abundant and we discuss the potential impact of introduced pollinators on endemic plant–pollinator associations. Given the wide-reaching role of native pollinators in island systems, yet lack of understanding of SWP pollinator suites, our study highlights the urgent need for more detailed pollinator research in the region. 相似文献
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Dermatophyte infections are extremely frequent worldwide and their epidemiological features vary according to the geographical area and have changed in the last decades. We studied the spectrum of dermatophytoses by means of a retrospective analysis involving 6,133 patients referred to the Mycology Service of the Dermatology Clinic of Policlinico Hospital - University of Bari, Italy during the period 2005-2010. The most frequent clinical forms were tinea unguium (39.2% of the total dermatophytoses), tinea corporis (22.7%) and tinea pedis (20.4%). There was a predominance of women for tinea unguium and corporis and of men for tinea pedis and especially tinea cruris. T. rubrum was the prevalent causative agent, implicated in 64% of total cases, followed by M. canis (14%) and T. mentagrophytes (10%). The retrospective evaluation of epidemiological data collected at our Clinic since 1975 showed a gradual decrease in the frequency of tinea cruris, tinea corporis, and tinea capitis over time. On the contrary, during the past two decades, there has been a progressive increase in the frequency of tinea pedis and especially of tinea unguium. In parallel with this changing pattern, the frequency of isolation of T. rubrum has shown a continuous increase during the last 35 years, whereas a progressive decline of the etiological role of T. violaceum, M. canis and even more of E. floccosum has been noted. 相似文献
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Emmer Alexander Abobarin-Adeagbo Abimbola Posa Andreas Jordan Berit Delank Karl-Stefan Staege Martin Sebastian Surov Alexander Zierz Stephan Kornhuber Malte Erich 《Molecular biology reports》2019,46(4):4085-4094
Molecular Biology Reports - The aetiology of inflammatory myopathies is not clearly known. A predominance of activated Cd8+ T lymphocytes in inflammatory infiltrates has already been detected.... 相似文献
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Genes/QTLs affecting flood tolerance in rice 总被引:8,自引:1,他引:7
K. Sripongpangkul G. B. T. Posa D. W. Senadhira D. Brar N. Huang G. S. Khush Z. K. Li 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2000,101(7):1074-1081
The adaptation of deepwater rice to flooding is attributed to two mechanisms, submergence tolerance and plant elongation.
Using a QTL mapping study with replicated phenotyping under two contrasting (water qualities) submergence treatments and AFLP
markers, we were able to identify several genes/QTLs that control plant elongation and submergence tolerance in a recombinant
inbred rice population. Our results indicate that segregation of rice plants in their responses to different flooding stress
conditions is largely due to the differential expression of a few key elongation and submergence tolerance genes. The most
important gene was QIne1 mapped near sd-1 on chromosome 1. The Jalmagna (the deepwater parent) allele at this locus had a very large effect on internal elongation
and contributed significantly to submergence tolerance under flooding. The second locus was a major gene, sub1(t), mapped to chromosome 9, which contributed to submergence tolerance only. The third one was a QTL, QIne4, mapped to chromosome 4. The IR74 (non-elongating parent) allele at this locus had a large effect for internal elongation.
An additional locus that interacted strongly with both QIne1 and QIne4 appeared near RG403 on chromosome 5, suggesting a complex epistatic relationship among the three loci. Several QTLs with
relatively small effects on plant elongation and submergence tolerance were also identified. The genetic aspects of these
flooding tolerance QTLs with respect to patterns of differential expression of elongation and submergence tolerance genes
under flooding are discussed.
Received: 13 December 1999 / Accepted: 14 March 2000<@head-com-p1a.lf>Communicated by G. Wenzel 相似文献
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Why do orangutans leave the trees? Terrestrial behavior among wild Bornean orangutans (Pongo pygmaeus wurmbii) at Tuanan,Central Kalimantan
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