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1.
O M Platonov T B Gerasimova P Ia Smal'ko S M Zheliabovskaia T V Korniushina 《Biokhimii?a (Moscow, Russia)》1981,46(11):2074-2081
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P. K. Golovatenko-Abramov E. A. Zhirkova E. G. Kolokolchikova V. S. Bocharova E. S. Platonov 《Russian Journal of Developmental Biology》2010,41(4):240-246
One of the phenotypic effects of mutation in the Hr gene in mice is disintegration of hair follicles and their degeneration into open funnel-shaped structures (utricles) opened
on skin surface and cysts located in the depth of the dermis. The aim of the current study consists in analysis of the process
of reparative regeneration of skin in homozygotous mice with one of the mutant alleles of the Hr gene—Hr
hr
. It is shown that epithelial cells that constitute the inner pavement of cysts take part in the process of epithelization
of deep skin wounds. This indicates that the competence of ectodermal cells in relation to inductive signals from injured
skin remains in Hr
hr
homozygote mice, in spite of the significant anatomic abnormalities of the hair follicles. 相似文献
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Sheree Yau Federico M Lauro Timothy J Williams Matthew Z DeMaere Mark V Brown John Rich John AE Gibson Ricardo Cavicchioli 《The ISME journal》2013,7(10):1944-1961
Organic Lake is a shallow, marine-derived hypersaline lake in the Vestfold Hills, Antarctica that has the highest reported concentration of dimethylsulfide (DMS) in a natural body of water. To determine the composition and functional potential of the microbial community and learn about the unusual sulfur chemistry in Organic Lake, shotgun metagenomics was performed on size-fractionated samples collected along a depth profile. Eucaryal phytoflagellates were the main photosynthetic organisms. Bacteria were dominated by the globally distributed heterotrophic taxa Marinobacter, Roseovarius and Psychroflexus. The dominance of heterotrophic degradation, coupled with low fixation potential, indicates possible net carbon loss. However, abundant marker genes for aerobic anoxygenic phototrophy, sulfur oxidation, rhodopsins and CO oxidation were also linked to the dominant heterotrophic bacteria, and indicate the use of photo- and lithoheterotrophy as mechanisms for conserving organic carbon. Similarly, a high genetic potential for the recycling of nitrogen compounds likely functions to retain fixed nitrogen in the lake. Dimethylsulfoniopropionate (DMSP) lyase genes were abundant, indicating that DMSP is a significant carbon and energy source. Unlike marine environments, DMSP demethylases were less abundant, indicating that DMSP cleavage is the likely source of high DMS concentration. DMSP cleavage, carbon mixotrophy (photoheterotrophy and lithoheterotrophy) and nitrogen remineralization by dominant Organic Lake bacteria are potentially important adaptations to nutrient constraints. In particular, carbon mixotrophy relieves the extent of carbon oxidation for energy production, allowing more carbon to be used for biosynthetic processes. The study sheds light on how the microbial community has adapted to this unique Antarctic lake environment. 相似文献
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Prokhorova E. I. Platonov A. A. Molkov S. I. Ignakhin V. S. Nazarov A. I. 《Plasma Physics Reports》2020,46(5):521-526
Plasma Physics Reports - In the region of the surface of the probe introduced into the plasma, there are emission flows that introduce changes in the determination of its parameters. Despite the... 相似文献
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Correlations between EEG findings and external respiration and gas exchange indices recorded prior to and after a single session of intermittent normobaric hypoxia were calculated by means of the Neirokartograf (MBN) program. Changes in the central regulation of respiration were observed for a period of more than one hour. The hypoxia caused a decline in EEG coherence in the left hemisphere and a decrease in the statistically significant correlations between the bioelectric rhythms of the , , and ranges and the external respiration and gas exchange indices. 相似文献
9.
Clonal analysis of parthenogenetic chimeric mouse embryos C57B1/6(PG)<-->BALB/c has shown that parthenogenetic cell clones C57BL/6 are present in the brain, liver, and kidneys of 14- and 18-day-old embryos. The content of the parthenogenetic component (PG) in these organs on day 18 was lower than on day 14, and, in some 18-day-old embryos, parthenogenetic cell clones were absent from the liver and/or kidneys. These data suggest that, during the embryogenesis of parthenogenetic chimeras, parthenogenetic cell clones of mostly endodermal and mesodermal origins were actively eliminated. Therefore, in such parthenogenetic adult chimeras, parthenogenetic clones of mostly ectodermal origins were preserved. In parthenogenetic chimeras CBA(PG)<-->BALB/c, parthenogenetic cell clones were actively eliminated at early embryonic stages, and, as a result, they were absent at the post-implantation stages. Hence, during development of parthenogenetic cell clones, the effects of genomic imprinting are expressed unequally in C57BL/6 and CBA mice. 相似文献
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