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M. Pickford 《Human Evolution》1987,2(1):71-89
The synoptic perspective of the fossil record of Old World monkeys presented in the preceding articles prompted the author
to explore aspects of cercopithecid biology which are difficult to examine with parochial evidence. These aspects include
origins and subsequent spread of monkeys through the Old World, relationship of major events in cercopithecoid history to
global climatic history, zoogeography and palaeozoogeography, and comparison of palaentological and neontological versions
of cercopithecid phylogenies. While there remain temporal and geographic gaps in the fossil record, difficulties in interpretations
will persist, but for the cercopithecids, the fossil data base is sufficiently comprehensive to yield a view of several of
the main events in their history. 相似文献
3.
M. Pickford 《Human Evolution》1990,5(1):1-20
Evidence concerning the geomorphological evolution of the Western Rift Valley, sedimentation within the valley and comparison
of the fossil mammalian faunas of Western Uganda and East Africa indicate that the mountain ranges which now flank the Western
Rift were uplifted in three or more stages beginning during the upper Miocene and that they reached climatically important
altitudes during the upper Pliocene, at which time they began to modify regional climatic patterns in East Africa. Their main
effect was the xerification of conditions over much of the region east of the mountains. The regional climatic effects due
to the mountain ranges were themselves modified by global climatic changes related to the onset of the Glacial Period, the
two phenomena combining to yield the Present day climatic regime of East Africa. As the climate changed, so did the flora
and fauna. Faunal response was of three main kinds: a) dispersal into East Africa of pre-existing forms already adapted to
more xeric conditions (many bovids, some cercopithecids), b) autochthonous evolution of forms adapted to mesic environments
into forms adapted to more xeric conditions (suids, elephantids, some bovids, hominids), c) displacement of species ranges
of those lineages unable to adapt to changing conditions (i.e. local extinctions) (Anancus, Brachypotherium). Autochthonous evolvers, including hominids, adopted two main strategies reflected in their hard anatomy: a) dietary shift
(suids, proboscideans, bovids and later Pliocene hominids) and b) locomotor changes (early Pliocene hominids). 相似文献
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M. Pickford 《Human Evolution》1991,6(3):263-268
Being based solely on neontological data, all «unique parent» evolutionary hypotheses, of which «Mitochondrial Eve» is one, fall into the category ofscala naturae. Mathematical treatment of neontological data bases, using cladistic approaches does not confer the status of scientific hypotheses onto such scenarios. Apart from these fundamental problems, such hypotheses are flawed on a number of other bases, including the fact that there is a proportion of parental contribution to mitochondrial lineages, despite widely publicised statements that mithocondrial DNA in mammals is «strictly» maternally inherited. Other weaknesses of «unique mother» hypotheses on that their proponents endeavour to describe the evolution of diploid organisms on the basis of variability in extant haploid organelles, the evolution of which is delinked from that of the diploid organism. A further difficulty is that it is not possible to reconstruct interspecific relationships on the basis of intraspecific variability. There is a general ignorance among proponents of «unique mother» hypotheses regarding the distribution of biological variability on the surface of the globe, a fact which renders the molecular clock inaccurate, and which upsets the simplistic proposal that molecular diversity equates with time. «Unique mother» scenarios are also invalidated by the presence of shared chromosome and other polymorphisms in african great apes and humans at similar percentages in the different lineages, a fact which indicates that these evolving populations did not experience «bottlenecks». These and other difficulties effectively refute the «Mitochondrial Eve» hypothesis, which in any case much resembles creationism of a special kind, in which the offspring of a breeding pair are visualised as belonging to a species different from its parents. Such extreme examples of the punctuational mode of evolution are highly likely to be incorrect. 相似文献
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Effects of low-chloride solutions on action potentials of sheep cadiac purkinje fibers 总被引:2,自引:0,他引:2
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The rapid repolarization during phase 1 of the action potential of sheep cardiac purkinje fibers has been attributed to a time- and voltage-dependent chloride current. In part, this conclusion was based on experiments that showed a substantial slowing of phase 1 when larger, presumably impermeant, anions were substituted for chloride in tyrode’s solution. We have re- examined the electrical effects of low-chloride solutions. We recorded action potentials of sheep cardiac purkinje fibers in normal tyrode’s solution and in low-chloride solutions made by substituting sodium propionate, acetylglycinate, methylsulfate, or methanesulfonate for the NaCl of Tyrode’s solution. Total calcium was adjusted to keep calcium ion activity of test solutions equal to that of control solutions. Propionate gave qualitatively variable results in preliminary experiments; it was not tested further. Low-chloride solutions made with the other anions gave much more consistent results: phase 1 and the notch that often occurs between phases 1 and 2 were usually unaffected, and the action potential duration usually increased. The only apparent change in the resting potential was a transient 3-6 mV depolarization when low-chloride solution was first admitted to the chamber, and a symmetrical transient hyperpolarization when chloride was returned to normal. If a time- and voltage-dependent chloride current exists in sheep cardiac purkinje fibers, our results suggest that it plays little role in generating phase 1 of the action potential. 相似文献