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Periyasami G Raghunathan R Surendiran G Mathivanan N 《Bioorganic & medicinal chemistry letters》2008,18(7):2342-2345
A series of novel dispirooxindolopyrrolizidine derivatives have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from proline and isatin with the dipolarophile (E)-2-arylidine-1-keto carbazoles. The synthesized cycloadducts were evaluated for antimicrobial activities. Compounds 7d and 7e showed relatively good antibacterial and antifungal activities. 相似文献
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