排序方式: 共有118条查询结果,搜索用时 15 毫秒
1.
Magdalena J. Rossowska Parvaneh Ghanel Tetsuo Nakamoto 《Biological trace element research》1995,50(3):229-236
The purpose of this study was to determine the relationship between concentrations of Zn and Cu and the activities of superoxide
dismutase and glutathione peroxidase in the heart and liver of young rat pups whose dams were fed a diet supplemented with
caffeine and/or Zn. Four groups of dams with their newborn pups were fed one of the following diets for 22 d: 20% protein
basal diet; the basal diet supplemented with caffeine (2 mg/100 body wt); the basal diet supplemented with Zn (300 mg/kg diet);
or the basal diet supplemented with caffeine plus Zn. The Cu levels in the livers of the pups were decreased by maternal intake
of the caffeine and Zn diet. The maternal intake of the caffeine diet increased Mn-superoxide dismutase (MnSOD) activity and
Cu, Zn-superoxide dismutase (CUZnSOD) in the heart of the pups. On the other hand, the activity of Cu,ZnSOD was significantly
reduced in the liver of pups whose dams consumed a caffeine, Zn, or caffeine plus Zn diet. Cu, ZnSOD activity in the liver
of the pups seems to be correlated with Cu levels in the tissue. Selenium-dependent glutathione peroxidase (GSH-Px) activities
in the heart and liver showed no difference among the groups. The effect of dietary caffeine and/or Zn on the activity of
antioxidant enzymes in the heart and liver were different in young rats. The activities of these enzymes in the heart were
lower than in the liver of 22-d-old rats. Our experiments indicate that the heart has limited defenses against the toxic effects
of peroxides when compared to the liver. 相似文献
2.
Mahboudi Somayeh Moosavi-Nasab Marzieh Kazemi Bahram Rahimpour Azam Eskandari Mohammad Hadi Mohammadian Omid Shams Forough 《Molecular biology reports》2021,48(5):4405-4412
Molecular Biology Reports - Monoclonal antibodies (mAbs) are widely employed as invaluable therapeutics for a vast number of human disorders. Several approaches have been introduced for the... 相似文献
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Malmir M. Sorooshzadeh A. Mohammadian R. Mokhtassi-Bidgoli A. 《Russian Journal of Plant Physiology》2021,68(1):158-168
Russian Journal of Plant Physiology - Having increased the temperature of different regions, global climate change can affect plants’ growth and development. This study aimed to explore the... 相似文献
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Mahanz Parvaneh Nejad Shirazi 《Historical Biology》2013,25(1-2):91-98
In northern Shiraz (SW Iran), Lower Cretaceous carbonate was studied in detail. In this study, nine species of dasycladacea algae were classified. There are different species of dasycladacea algae which belong to seven different genera: Actinoporella, Cylindroporella, Dissocladela, Heteroporella, Neomeris, Salpingoporella, Trinocladus; one species of udoteaceae belongs to Bouenia; one species of acetabulariaceae belongs to Clypeina and the microproblematicum Coptocampylodon was also seen. Among the green algae, dasycladaceae and acetabulariceae are the most frequent and udoteaceans are rare in Zagros Mountains. The genus of Trinocladus is a new record for Lower Cretaceous (Upper Albian) in SW Iran. 相似文献
6.
Ali Mohammadian Seyed Javad Mowla Elahe Elahi Mahmood Tavallaei Mohammad Reza Nourani Yu Liang 《Biotechnology letters》2013,35(6):843-851
Low-density quantitative real-time PCR (qPCR) arrays are often used to profile expression patterns of microRNAs in various biological milieus. To achieve accurate analysis of expression of miRNAs, non-biological sources of variation in data should be removed through precise normalization of data. We have systematically compared the performance of 19 normalization methods on different subsets of a real miRNA qPCR dataset that covers 40 human tissues. After robustly modeling the mean squared error (MSE) in normalized data, we demonstrate lower variability between replicates is achieved using various methods not applied to high-throughput miRNA qPCR data yet. Normalization methods that use splines or wavelets smoothing to estimate and remove Cq dependent non-linearity between pairs of samples best reduced the MSE of differences in Cq values of replicate samples. These methods also retained between-group variability in different subsets of the dataset. 相似文献
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Biomechanics and Modeling in Mechanobiology - Targeted drug delivery is an impressive topic that attracted the attention of many scientists in various scientific communities. Magnetic drug... 相似文献
8.
Arash Soltani Kolsoum Rezaie Kahkhaie Saeed Mohammadian Haftcheshmeh Ahmad Ali Jalali Nezhad Masoud Mashhadi Akbar Boojar 《Journal of cellular biochemistry》2019,120(5):7573-7580
Nowadays, increased use of nanomaterials in industry and biomedicine poses potential risks to human health and the environment. Studying their possible toxicological effects is therefore of great significance. The present investigation was designed to examine the status of oxidative stress induced by nanoparticles (NPs) of ferric oxide (Fe2O 3) and titanium oxide (TiO 2) with their micro-sized counterpart on mouse lung and bone marrow–derived normal tissue cells. We assessed the induction of oxidative stress by measuring its indicators such as antioxidant scavenging activity of superoxide dismutase and catalase as well as malondialdehyde concentration. Moreover, colony formation of bone marrow cells was assayed following induction with colony stimulating factor (CSF) from lung cells. NPs had a more potent stimulatory effect on the oxidative stress status than their micron-sized counterparts. In addition, the highest level of oxidative stress derived from TiO 2 NPs was observed in both tissue types. Cotreatment with NPs and the antioxidant α-tocopherol reduced antioxidant activities and membrane lipid peroxidation (LPO) in the lung cells, but increased CSF-induced colony formation activity of bone marrow cells, suggesting that oxidative stress may be the cause of the cytotoxic effects of NPs. It is concluded that free radicals generated following exposure to NPs resulted in significant oxidative stress in mouse cells, indicated by increased LPO and antioxidant enzyme activity and decreased colony formation. 相似文献
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Ibrahim El-Serafi Parvaneh Afsharian Ali Moshfegh Moustapha Hassan Ylva Terelius 《PloS one》2015,10(11)