排序方式: 共有43条查询结果,搜索用时 15 毫秒
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A. F. Aleksandrov A. K. Petrov K. V. Vavilin E. A. Kralkina P. A. Neklyudova A. M. Nikonov V. B. Pavlov A. A. Ayrapetov V. V. Odinokov V. A. Sologub G. Ya. Pavlov 《Plasma Physics Reports》2016,42(3):290-292
Results of an experimental study of the helicon discharge plasma parameters in a prototype of a hybrid RF plasma system equipped with a solenoidal antenna are described. It is shown that an increase in the external magnetic field leads to the formation of a plasma column and a shift of the maximum ion current along the discharge axis toward the bottom flange of the system. The shape of the plasma column can be controlled via varying the configuration of the magnetic field. 相似文献
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Eroshenko GA Odinokov GN Kukleva LM Kutyrev VV 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》2012,(3):90-95
Literature data and results of our experimental studies on genetic base of biochemical differentiation of Yersinia pestis strains of various subspecies and biovars are summarized in the review. Data on variability of genes coding biochemical features (sugar and alcohol fermentation, nitrate reduction), the differential development of which are the base of existing phenotypic schemes of Y. pestis strains classification, are presented. Variability of these genes was shown to have possible use for the development of genetic classification of Y. pestis strains of various subspecies and biovars. 相似文献
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A study of bacterial surface oligosaccharides were investigated among
different strains of Neisseria gonorrhoeae to correlate structural features
essential for binding to the MAb 2C7. This epitope is widely expressed and
conserved in gonococcal isolates, characteristics essential to an effective
candidate vaccine antigen. Sample lipooligosaccharides (LOS), was prepared
by a modification of the hot phenol-water method from which de-O-acetylated
LOS and oligosaccharide (OS) components were analyzed by ES-MS-CID-MS and
ES-MSnin a triple quadrupole and an ion trap mass spectrometer,
respectively. Previously documented natural heterogeneity was apparent from
both LOS and OS preparations which was admixed with fragments induced by
hydrazine and mild acid treatment. Natural heterogeneity was limited to
phosphorylation and antenni extensions to the alpha-chain. Mild acid
hydrolysis to release OS also hydrolyzed the beta(1-->6) glycosidic
linkage of lipid A. OS structures were determined by collisional and
resonance excitation combined with MS and multistep MSn which provided
sequence information from both neutral loss, and nonreducing terminal
fragments. A comparison of OS structures, with earlier knowledge of MAb
binding, enzyme treatment, and partial acid hydrolysis indicates a generic
overlapping domain for 2C7 binding. Reoccurring structural features include
a Hepalpha(1-->3)Hepbeta(1-->5)KDO trisaccharide core branched on the
nonreducing terminus (Hep-2) with an alpha(1-->2) linked GlcNAc
(gamma-chain), and an alpha-linked lactose (beta-chain) residue. From the
central heptose (Hep-1), a beta(1-->4) linked lactose (alpha-chain),
moiety is required although extensions to this residue appear unnecessary.
相似文献
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I. Yu. Ponedel’kina E. S. Lukina V. N. Odinokov 《Russian Journal of Bioorganic Chemistry》2008,34(1):1-23
The modern state of chemical modification of hyaluronic acid, chondroitin sulfates, and heparin is considered, and the possible application of modified glycosaminoglycans as potential drugs is discussed. 相似文献
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E.?V.?TretyakovaEmail author I.?E.?Smirnova E.?V.?Salimova T.?M.?Pashkova O.?L.?Kartashova V.?N.?Odinokov L.?V.?Parfenova 《Russian Journal of Bioorganic Chemistry》2017,43(3):317-322
A number of nitrogen-, bromine-, and sulfur-containing derivatives of diene adducts of levopimaric acid have been synthesized. The testing of the compounds on Staphylococcus aureus and Klebsiella pneumoniae bacteria has shown that the compounds possess a weak antimicrobial activity. 相似文献
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Savchenko RG Urasaeva YR Galyautdinov IV Afonkina SR Khalilov LM Dolgushin FM Odinokov VN 《Steroids》2011,76(6):603-606
A Pd-C-catalyzed hydrogenation in methanol and in the presence of sodium methylate is a simple, convenient and high yielding reduction method to convert the 7,14-dien-6-one ecdysteroids to their corresponding 7,8α-dihydro-14α-deoxyecdysteroids. 相似文献
10.
Information on the synthesis and biological activity of natural and synthetic analogues of alpha-tocopherol with a modified side chain is systematized. These compounds are of interest as vitamin E metabolites, hydrophilic antioxidants, and precursors of drugs with combined pharmacological properties useful in therapy of pathological disorders caused by oxidative stress. 相似文献