全文获取类型
收费全文 | 267篇 |
免费 | 18篇 |
专业分类
285篇 |
出版年
2022年 | 1篇 |
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 3篇 |
2018年 | 3篇 |
2016年 | 3篇 |
2015年 | 8篇 |
2014年 | 5篇 |
2013年 | 14篇 |
2012年 | 18篇 |
2011年 | 13篇 |
2010年 | 10篇 |
2009年 | 8篇 |
2008年 | 14篇 |
2007年 | 16篇 |
2006年 | 12篇 |
2005年 | 12篇 |
2004年 | 8篇 |
2003年 | 10篇 |
2002年 | 9篇 |
2001年 | 10篇 |
2000年 | 17篇 |
1999年 | 8篇 |
1998年 | 2篇 |
1997年 | 7篇 |
1996年 | 4篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 9篇 |
1991年 | 5篇 |
1990年 | 4篇 |
1989年 | 3篇 |
1988年 | 4篇 |
1987年 | 4篇 |
1986年 | 2篇 |
1985年 | 6篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1979年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1972年 | 2篇 |
1971年 | 1篇 |
1970年 | 2篇 |
1968年 | 1篇 |
1967年 | 1篇 |
排序方式: 共有285条查询结果,搜索用时 15 毫秒
1.
A congenital hypothyroidism complicated by ventricular septal defects which was treated with L-triiodothyronine (L-T3) alone from 1 5/12 to 25 years, is described. The patient's growth and development was satisfactory and without side effects. It suggests that L-T3 may be a safe drug for long term treatment of congenital hypothyroidism. 相似文献
2.
N Sasaki T Tsuyusaki H Nakamura K Sanayama H Niimi H Nakajima 《Endocrinologia japonica》1985,32(1):39-44
Hyporesponsiveness of GH to insulin-induced hypoglycemia has previously been reported in hyperthyroid patients. In order to clarify the GH secretion in thyrotoxic patients, sleep-related increases in the serum GH concentration were investigated. Eight thyrotoxic females ranging in age from 7 to 15 were treated with PTU. Blood samples for measurement of GH were drawn every 15 minutes during the first few hours of sleep before and during the treatment lasting about three months. The mean maximum serum GH level before the treatment was 10.0 +/- 5.5 ng/ml (mean +/- SD); this rose to 23.2 +/- 14.6 ng/ml (P less than 0.02) during the treatment. The maximum value of more than 10 ng/ml was detected in only 3 out of the 8 patients before treatment. On the other hand, serum GH levels during PTU administration rose to above 10 ng/ml in all patients except one. It was revealed that sleep-related elevations of GH occurred early in sleep and in close association with a slow-wave EEG pattern. The results show that sleep-related GH release is low in the hyperthyroid state, but becomes significantly elevated during PTU administration. However, even in the hyperthyroid state, the sleep-related secretion of GH is closely correlated with the slow-wave sleep stage as in the euthyroid condition. 相似文献
3.
Pituitary prolactin (PRL) responses to 4-day continuous infusion of thyrotropin-releasing hormone (TRH) and vasoactive intestinal polypeptide (VIP) were investigated in unanesthetized male rats using Alzet osmotic minipumps. The TRH dose infused was 3.6 micrograms/day and the VIP dose was 32.8 micrograms/day. Infusion of TRH with osmotic pumps elevated the plasma PRL level compared to controls over the 4-day infusion period. However, mean levels of PRL tended to decrease during the 4-day infusion. On the other hand, continuous VIP infusion elicited a significant continuous PRL release over the 4-day infusion period. Thus, it may be said that the PRL responses to infused TRH and VIP were maintained during the 4-day infusion. 相似文献
4.
Effects of high osmotic media on the shape and deformability of RBC were examined for determining increasing factors of blood viscosity. Dog blood and Urographin (a hypertonic contrast medium) were used; the plasma osmolality was changed by Urografin suspended in blood. The viscosity was measured for normal RBC and glutaraldehyde-treated RBC suspensions with a cell volume concentration. The RBC deformability was evaluated from the difference in viscosity between the two suspensions. It was shown that normal RBC suspension increased the viscosity with increase in osmolality at high shear rate; hardened RBC suspension decreased the viscosity with increase in osmolality. It was concluded that the RBC deformability decreased with increasing osmolality. 相似文献
5.
The quantity of translatable mRNA of glucose-6-phosphate dehydrogenase (D-glucose-6-phosphate: NADP+ 1-oxidoreductase, EC 1.1.1.49) in primary cultures of adult rat hepatocytes subjected to different hormonal conditions was determined with a reticulocyte-lysate, cell-free system. The level of glucose-6-phosphate dehydrogenase mRNA was about 5-fold higher in the presence of insulin than in its absence. This increase of glucose-6-phosphate dehydrogenase mRNA reached a maximum 12 h after the addition of insulin. The maximum level of induction of glucose-6-phosphate dehydrogenase mRNA required 10(-8) M insulin. Glucagon and triiodothyronine had no effect on the glucose-6-phosphate dehydrogenase mRNA level. The increase of glucose-6-phosphate dehydrogenase activity correlated with the increase in level of mRNA of this enzyme. This suggests that the changes in glucose-6-phosphate dehydrogenase activity in response to the above hormonal changes are primarily due to changes in the amount of mRNA coding for this enzyme. 相似文献
6.
7.
Unrolling due to blue light (B) irradiation of the second leavesdetached from 8-day-old rice (Oryza saliva L.) seedlings wassimilar to that reported previously for nondetached leaves.The effect of B was counteracted by irradiation with red light(R). The counteracting effect of R was reversed by subsequentirradiation with far-red light (FR). When the detached leaf was irradiated with B passed througha 1-mm-wide slit 5, 8, 10, 12 or 15 mm from the leaf tip, irradiation10 mm from the leaf tip was the most effective. The effect of a 1 mm-wide-B irradiation 10 mm from the leaftip was counteracted by a 1 mm-wide-R irradiation at the sameposition, but not by irradiations at the other points. The counteractingeffect of R was reversed by a 1 mm-wide-FR irradiation at thesame position. This suggests that the excitation or the reactionof the B photoreceptor(s) is affected directly by the PFR formof phytochrome. The dose-response curve for the unrolling caused by B showeda simple Bunsen-Roscoe relation without two peaks, which differsfrom that for the phototropism in Avena caused by B. (Received August 21, 1980; Accepted December 20, 1980) 相似文献
8.
9.
We investigated the effect of background scene on the human visual perception of depth orientation (i.e., azimuth angle) of three-dimensional common objects. Participants evaluated the depth orientation of objects. The objects were surrounded by scenes with an apparent axis of the global reference frame, such as a sidewalk scene. When a scene axis was slightly misaligned with the gaze line, object orientation perception was biased, as if the gaze line had been assimilated into the scene axis (Experiment 1). When the scene axis was slightly misaligned with the object, evaluated object orientation was biased, as if it had been assimilated into the scene axis (Experiment 2). This assimilation may be due to confusion between the orientation of the scene and object axes (Experiment 3). Thus, the global reference frame may influence object orientation perception when its orientation is similar to that of the gaze-line or object. 相似文献
10.
Chihiro Minatsuki Nobutake Yamamichi Takeshi Shimamoto Hikaru Kakimoto Yu Takahashi Mitsuhiro Fujishiro Yoshiki Sakaguchi Chiemi Nakayama Maki Konno-Shimizu Rie Matsuda Satoshi Mochizuki Itsuko Asada-Hirayama Yosuke Tsuji Shinya Kodashima Satoshi Ono Keiko Niimi Toru Mitsushima Kazuhiko Koike 《PloS one》2013,8(7)