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Ben Kridis-Rejeb Wala Ben Ayed-Guerfali Dorra Ammous-Boukhris Nihel Ayadi Wajdi Kifagi Chamseddine Charfi Slim Saguem Ines Sellami-Boudawara Tahia Daoud Jamel Khanfir Afef Mokdad-Gargouri Raja 《Molecular biology reports》2020,47(9):6507-6516
Molecular Biology Reports - Male Breast Cancer (MBC) is a rare and aggressive disease that is associated with genetic factors. Mutations in BRCA1 and BRCA2 account for... 相似文献
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Mariam Siala Radhouane Gdoura Mohamed Younes Hela Fourati Ilhem Cheour Nihel Meddeb Naceur Bargaoui Sofien Baklouti Slaheddine Sellami Markus Rihl & Adnene Hammami 《FEMS immunology and medical microbiology》2009,55(2):178-186
We aimed to determine the frequency of Chlamydia trachomatis DNA in the synovial compartment of 34 arthritic patients. Chlamydia trachomatis DNA was detected using a nested PCR targeting the cryptic plasmid, the 16S rRNA gene and the outer membrane protein 1 gene. The presence of serum immunoglobulin (Ig)G and IgA antibodies against C. trachomatis was studied by a microimmunofluorescence assay and by an enzyme-linked immunosorbent assay, respectively. Synovial samples from 20 of 34 (59%) patients [nine with reactive arthritis (ReA), seven with undifferentiated oligoarthritis (UOA), two with rheumatoid arthritis and two with osteoarthritis] were positive for at least one C. trachomatis DNA sequence by nested PCR. The high sensitivity results most likely from the combination of a standardized automated MagNA Pure extraction method, PCR targeting three different C. trachomatis genes and the screening for C. trachomatis in synovial tissue and fluid samples. There was no correlation between the presence of C. trachomatis DNA in the joint and a Chlamydia -specific serologic response. Our data support that PCR is the method of choice to establish the diagnosis of Chlamydia -induced arthritis in patients with ReA. We suggest that this diagnosis might also be considered in C. trachomatis -positive patients previously classified as UOA. 相似文献
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Nas Fatima Aissaoui Nadia Mahjoubi Mouna Mosbah Amor Arab Mounia Abdelwahed Soukaina Khrouf Rim Masmoudi Ahmed-Salaheddine Cherif Ameur Klouche-Khelil Nihel 《International microbiology》2021,24(3):455-470
International Microbiology - The reemergence of infectious diseases and resistant pathogens represents a serious problem for human life. Hence, the screening for new or alternative antimicrobial... 相似文献
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