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O. L. Nesterova 《Entomological Review》2007,87(7):822-829
A comparative morphological characteristic of the mouthparts of representatives of five Palaearctic genera of the subtribe Entomoscelidina is given. 相似文献
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Mapping of the silver fox genes: assignments of the genes for ME1, ADK, PP, PEPA, GSR, MPI, and GOT1
T B Nesterova N B Rubtsov S M Zakian V G Matveeva A S Graphodatsky 《Cytogenetics and cell genetics》1991,56(2):125-127
Evidence is presented for the assignment of seven fox genes on the basis of the segregation data for chromosomes and enzymes of fox x Chinese hamster somatic cell hybrids. The chromosomal loci of the following enzyme genes were determined: ME1, VFU1; ADK and PP, VFU4; PEPA, VFU5; GSR, VFU7; and MPI and GOT1, VFU15. The localization of these genes now extends the fox genetic map to 22 mapped genes. Based on comparative analysis of mammalian genetic maps, karyotype evolution in Carnivora is discussed. 相似文献
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Experiments on the introduction of the regulatory subunit of cAMP-dependent protein kinase type II (RII) into NIH 3T3 cells clearly demonstrated its translocation into the nucleus. The labelled protein was incorporated into erythrocyte ghosts and their fusion with the cells was carried out. The dynamics of distribution of the labelled RII in NIH 3T3 cells was studied by the method of historadiography. It was found that during the next few hours after its penetration into the cytoplasm, the protein translocates into the nucleus and concentrates in the immediate proximity to the nucleoli. 相似文献
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At the height of radiation sickness (7-8 days after irradiation) the accretion of proteins of "acute phase" in rat blood was accompanied by diminution of diminution of hydroxylating activity of microsomes determined by the rate of aminopyrine demethylation. There was an invert correlation between these two indices, and the correlation coefficient was -0.9. 相似文献
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Expression of X-linked genes for G6PD and alpha-GAL was studied in female interspecific hybrids of Microtus. The G6PD and alpha-GAL isozymes of Microtus arvalis were found to predominate in all cases when a species carrying a heterochromatin block on the X-chromosome served as one partner of hybridization and M. arvalis containing no heterochromatin block served as another. The proportions of G6PD and alpha-GAL parental forms were approx. equal in hybrid females when both species participating in hybridization contained heterochromatin blocks on X-chromosomes. Cytological analysis for revealing active and nonactive X-chromosomes on metaphase spreads of hybrid females supports the biochemical data. Non-random inactivation of X-chromosomes carrying the heterochromatin blocks in the interspecific hybrids with M. arvalis and a random one, when both parents contain heterochromatin blocks on the X-chromosomes are supposed to be the cause for the phenomenon observed. The study provided data supporting our previous hypothesis that heterochromatin affects the X-chromosome inactivation process in interspecific hybrid voles. 相似文献
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Nuclear translocation of cAMP-dependent protein kinase 总被引:2,自引:0,他引:2
M. V. Nesterova Kh. A. Ulmasov A. Abdukarimov A. A. Aripdzhanov E. S. Severin 《Experimental cell research》1981,132(2):367-373
A study was made of nuclear translocation of cAMP-dependent protein kinase and its subunits, as well as of the binding of these proteins to metaphase chromosomes. The CHO cell cultures were treated with 3H-labelled protein kinase and its subunits. The results indicate that cAMP-dependent protein kinase became translocated into the nucleus in a dissociated state and that the subunits have specific binding sites on chromatin. Transformation of normal mouse fibroblasts by virus SV40 interferes with the nuclear translocation of the regulatory subunit. The process is restored when the level of cAMP in the system is increased. Binding of the regulatory subunit to metaphase chromosomes of cells transformed by virus SV40 does not change. In the case of spontaneous cancer (KB cells) translocation of the regulatory subunit remains unaffected, whereas acceptance of the protein by the metaphase chromosomes is impeded. The results of this work suggest that compartmentalization of cAMP-dependent protein kinase—and particularly of its regulatory subunit—in the cell is highly significant for cellular processes. Disorders arising as a result of neoplastic transformation involve changes in nuclear translocation of the regulatory subunit and in its binding to the structural elements of the genome. 相似文献
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A D Nazarov L S Strachunski? A A Firsov N A Petrachenkova V I Sushkova R D Sheliakina E Z Kagan L Ia Nesterova N I Sinitsyna 《Antibiotiki i khimioterapii͡a》1991,36(2):36-39
Pharmacokinetics of erythromycin base was studied clinically in children not older than 14 years treated with new children dosage forms of the antibiotic i. e. 0.1 and 0.25 g enteric coated tablets and 0.06 and 0.125 g suppositories. It was noted that the new dosage forms were characterized by higher availability which was 2.5-3 times higher than that after using the erythromycin base tablets without the coating. Systematic increasing of erythromycin availability after the use of the rectal suppositories was observed with increasing of the children age. Absolute absorption in newborns, sucklings and children over 1 year amounted to 28, 36 and 54 per cent respectively. 相似文献