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The study on traditional knowledge and experience of using plants by Uyghurs folk people has a potential application in socio economic development and resource protection. Populus euphratica Oliv and Ppruinosa Schrenk are major plants in Taklimakan desert ecosystem of Xinjiang. This study aims to ascertain the Lopnur Uyghurs traditional knowledge on two Populus species and their cultural system related to these species. We investigated the key informants for interviews on using Populus plants. The Populus plants were used for various purposes. The white alkali crystals are using for the treatment of bloating, sore throat, stomach ulcers, duodenal ulcers and indigestion and also in soda, while black crystal is used for the treatment of back pain, leg pain, swelling and relieve pain. Alkali crystals are even used as shampoo after a simple processing and also as a laundry detergent. Populus plants water is applied as a treatment of neurasthenia. It is also used for anti aging, reducing blood pressure, high cholesterol and heart morbidity. Plants foliages are used as veterinary medicine such as bloating and rot of muscular and stomach of livestock. In addition, Lopnur people used the plants to build the Desert Ecological Park and controlling desertification. This article ascertained the two Populus speceis and Lopnur Uyghurs cultural system. Present study will improve the conservation of Lopnur Uyghurs folk indigenous/ traditional knowledge on Populus plants and to promote the sustainable development in the socio economic diversity.  相似文献   
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