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排序方式: 共有125条查询结果,搜索用时 31 毫秒
1.
AlateratioofMyzuspersicaeSulzerwasgreatlycloserinrelationshiptocertaininclusionintherapecrop-QingyouⅡ,suchastryptophan,ratioofcontentsofsolublesugartoproteinandmeancrowdingnessunderconditionsofvariedmateproportionoffertilizers-N,P,K.Thefollowinginclusionintherapecropwerealsorelatedtotheratioofalatate:asperticacid,troeoninie,serine,glutancicacid,phenylalanine,lysine,histidine,valine,methionine,isoleucine,leucine,solublesugarandwater-solubleprotein. 相似文献
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高原适应过程中大鼠脑内β-内啡肽含量变化的研究 总被引:1,自引:0,他引:1
选用成年雄性Wistar大鼠,由平原(海拔5m,上海)直接运送到高原(2261m,西宁和3460m,天峻)。以放射免疫分折法研究了大鼠在高原24h.急性缺氧期和30d慢性缺氧期中枢脑内β-内啡肽样免疫活性物质(β-EP)的含量变化。结果表明:1.大鼠在两个不同海拔(2261m,3460m)环境24h急性缺氧期与平原对照组相比,脑垂体内β-EP含量降低非常显著(P<0.01),纹状体、丘脑、下丘脑、桥-延脑、海马内β-EP含量均增加非常显著(P<0.01)。2.大鼠在3460m高原30d慢性习服期,垂体及各脑区内β-EP的含量变化呈时相性:即1—3d均呈进行性增加(P<0.01):3-15d呈持续性减少,除中脑、纹状体、丘脑外,均为P<0.01。15-30d垂体、丘脑、皮层、纹状体内β-EP含量仍持续减少(毒体、皮层P<0.01),桥-延脑、下丘脑、海马趋于回升(P<0.01),中脑亦趋于回升(P>0.05)。脑内β-EP的这种变化可能具有十分重要的生物学意义。 相似文献
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Daniel E. Impoinvil Mong How Ooi Peter J. Diggle Cyril Caminade Mary Jane Cardosa Andrew P. Morse Matthew Baylis Tom Solomon 《PLoS neglected tropical diseases》2013,7(8)
Background
Japanese encephalitis (JE) is the leading cause of viral encephalitis across Asia with approximately 70,000 cases a year and 10,000 to 15,000 deaths. Because JE incidence varies widely over time, partly due to inter-annual climate variability effects on mosquito vector abundance, it becomes more complex to assess the effects of a vaccination programme since more or less climatically favourable years could also contribute to a change in incidence post-vaccination. Therefore, the objective of this study was to quantify vaccination effect on confirmed Japanese encephalitis (JE) cases in Sarawak, Malaysia after controlling for climate variability to better understand temporal dynamics of JE virus transmission and control.Methodology/principal findings
Monthly data on serologically confirmed JE cases were acquired from Sibu Hospital in Sarawak from 1997 to 2006. JE vaccine coverage (non-vaccine years vs. vaccine years) and meteorological predictor variables, including temperature, rainfall and the Southern Oscillation index (SOI) were tested for their association with JE cases using Poisson time series analysis and controlling for seasonality and long-term trend. Over the 10-years surveillance period, 133 confirmed JE cases were identified. There was an estimated 61% reduction in JE risk after the introduction of vaccination, when no account is taken of the effects of climate. This reduction is only approximately 45% when the effects of inter-annual variability in climate are controlled for in the model. The Poisson model indicated that rainfall (lag 1-month), minimum temperature (lag 6-months) and SOI (lag 6-months) were positively associated with JE cases.Conclusions/significance
This study provides the first improved estimate of JE reduction through vaccination by taking account of climate inter-annual variability. Our analysis confirms that vaccination has substantially reduced JE risk in Sarawak but this benefit may be overestimated if climate effects are ignored. 相似文献6.
Po-Han Chan Bhaswati Ghosh Hong-Zheng Lai Hwei-Ling Peng Kwok Kong Tony Mong Yu-Chie Chen 《PloS one》2013,8(3)
Glycan-bound nanoprobes have been demonstrated as suitable sensing probes for bacteria containing glycan binding sites. In this study, we demonstrated a facile approach for generating glycan-bound gold nanoclusters (AuNCs). The generated AuNCs were used as sensing probes for corresponding target bacteria. Mannose-capped AuNCs (AuNCs@Mann) were generated and used as the model sensors for target bacteria. A one-step synthesis approach was employed to generate AuNCs@Mann. In this approach, an aqueous solution of tetrachloroauric acid and mannoside that functionized with a thiol group (Mann-SH) was stirred at room temperature for 48 h. The mannoside functions as reducing and capping agent. The size of the generated AuNCs@Mann is 1.95±0.27 nm, whereas the AuNCs with red photoluminescence have a maximum emission wavelength of ∼630 nm (λexcitation = 375 nm). The synthesis of the AuNCs@Mann was accelerated by microwave heating, which enabled the synthesis of the AuNCs@Mann to complete within 1 h. The generated AuNCs@Mann are capable of selectively binding to the urinary tract infection isolate Escherichia coli J96 containing the mannose binding protein FimH expressed on the type 1 pili. On the basis of the naked eye observation, the limit of detection of the sensing approach is as low as ∼2×106 cells/mL. 相似文献
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Remote homology detection refers to the detection of structural homology in proteins when there is little or no sequence similarity. In this article, we present a remote homolog detection method called SVM-HMMSTR that overcomes the reliance on detectable sequence similarity by transforming the sequences into strings of hidden Markov states that represent local folding motif patterns. These state strings are transformed into fixed-dimension feature vectors for input to a support vector machine. Two sets of features are defined: an order-independent feature set that captures the amino acid and local structure composition; and an order-dependent feature set that captures the sequential ordering of the local structures. Tests using the Structural Classification of Proteins (SCOP) 1.53 data set show that the SVM-HMMSTR gives a significant improvement over several current methods. 相似文献
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Park HH Park C Kim KS Kwon OS Han SS Hwang JS Lee SM Seong SI Kang SW Kim HR Lee BH 《Zoological science》2003,20(2):111-119
Effects of 20-hydroxyecdysone and serotonin on the morphological development and the survival of antennal lobe neurons from day-2 pupal brains of the silk moth Bombyx mori were investigated in vitro. Four morphologically distinct neuronal types could be identified in the cultured antennal lobe neurons: unipolar, bipolar, multi-polar and projection neurons. Antennal lobe neurons in culture with 20-hydroxyecdysone and serotonin showed different patterns of the morphological development from those described in Manduca sexta. Projection neurons extend their neurites remarkably by 20-hydroxyecdysone in B. mori, but there is no extension from antennal lobe neurons in M. sexta. Multi-polar neurons conspicuously increase only formation of new branches from their primary neurites by serotonin in B. mori, but there are both extension and branching of the neurites in M. sexta. On day-5, antennal lobe neurons in lower titers of 20-hydroxyecdysone had significantly higher survival rates than those in higher titers. Neurons cultured for 7 days at different levels of 20-hydroxyecdysone generally showed significantly lower survival rates than neurons cultured for 5 days under the same conditions. 相似文献
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