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Drew Weissman Mohamad-Gabriel Alameh Thushan de Silva Paul Collini Hailey Hornsby Rebecca Brown Celia C. LaBranche Robert J. Edwards Laura Sutherland Sampa Santra Katayoun Mansouri Sophie Gobeil Charlene McDanal Norbert Pardi Nick Hengartner Paulo J.C. Lin Ying Tam Pamela A. Shaw David C. Montefiori 《Cell host & microbe》2021,29(1):23-31.e4
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Valentina Tiporlini Selam Ahderom Peter Pratten Kamal Alameh 《Journal of biophotonics》2021,14(2):e202000243
The inability of current catheter ablation procedures to accurately monitor lesion formation limits their safety and efficacy. An advanced fully integrated radiofrequency (RF)/optical coherence tomography (OCT) ablation catheter is developed, which enables real-time monitoring during ablation. An OCT fiber array is especially designed, developed and integrated into an off-the-shelf irrigated RF ablation catheter. In-vitro experimental studies performed on poultry and ovine hearts demonstrate the ability of the integrated RF/OCT system to provide information on the quality and orientation of catheter/wall contact. Experimental results show that adipose tissue can be accurately identified from normal myocardial tissue with 94% accuracy and lesion formation is monitored with an overall accuracy of 93%. The ability to predict pop events is also demonstrated, with an accuracy of 86%. 相似文献
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